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Brain disorder

MedGen UID:
14214
Concept ID:
C0006111
Disease or Syndrome
Synonym: Brain disease
SNOMED CT: Disorder of brain (81308009)
 
Monarch Initiative: MONDO:0005560

Definition

A non-neoplastic or neoplastic disorder that affects the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBrain disorder

Professional guidelines

PubMed

Guzman-Martinez L, Calfío C, Farias GA, Vilches C, Prieto R, Maccioni RB
J Alzheimers Dis 2021;82(s1):S51-S63. doi: 10.3233/JAD-201059. PMID: 33523002
Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y
Nat Rev Neurol 2019 Sep;15(9):519-539. Epub 2019 Jul 19 doi: 10.1038/s41582-019-0226-9. PMID: 31324898
Volkow ND, Boyle M
Am J Psychiatry 2018 Aug 1;175(8):729-740. Epub 2018 Apr 25 doi: 10.1176/appi.ajp.2018.17101174. PMID: 29690790

Recent clinical studies

Etiology

Klein P, Kaminski RM, Koepp M, Löscher W
Nat Rev Drug Discov 2024 Sep;23(9):682-708. Epub 2024 Jul 22 doi: 10.1038/s41573-024-00981-w. PMID: 39039153
Grangeon L, Lange KS, Waliszewska-Prosół M, Onan D, Marschollek K, Wiels W, Mikulenka P, Farham F, Gollion C, Ducros A; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2023 Feb 20;24(1):12. doi: 10.1186/s10194-023-01547-8. PMID: 36800925Free PMC Article
Mewasingh LD, Chin RFM, Scott RC
Dev Med Child Neurol 2020 Nov;62(11):1245-1249. Epub 2020 Aug 3 doi: 10.1111/dmcn.14642. PMID: 32748466
Garg RK, Mahadevan A, Malhotra HS, Rizvi I, Kumar N, Uniyal R
Rev Med Virol 2019 Sep;29(5):e2058. Epub 2019 Jun 24 doi: 10.1002/rmv.2058. PMID: 31237061
Huang R, Wang K, Hu J
Nutrients 2016 Aug 6;8(8) doi: 10.3390/nu8080483. PMID: 27509521Free PMC Article

Diagnosis

Dorsey ER, Bloem BR
J Parkinsons Dis 2024;14(3):451-465. doi: 10.3233/JPD-230357. PMID: 38217613Free PMC Article
Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT
Nat Rev Dis Primers 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y. PMID: 33986301Free PMC Article
Begemann MJ, Brand BA, Ćurčić-Blake B, Aleman A, Sommer IE
Psychol Med 2020 Nov;50(15):2465-2486. Epub 2020 Oct 19 doi: 10.1017/S0033291720003670. PMID: 33070785Free PMC Article
Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y
Nat Rev Neurol 2019 Sep;15(9):519-539. Epub 2019 Jul 19 doi: 10.1038/s41582-019-0226-9. PMID: 31324898
Moulin S, Leys D
Curr Opin Neurol 2019 Feb;32(1):54-59. doi: 10.1097/WCO.0000000000000620. PMID: 30239360

Therapy

Klein P, Kaminski RM, Koepp M, Löscher W
Nat Rev Drug Discov 2024 Sep;23(9):682-708. Epub 2024 Jul 22 doi: 10.1038/s41573-024-00981-w. PMID: 39039153
Dorsey ER, Bloem BR
J Parkinsons Dis 2024;14(3):451-465. doi: 10.3233/JPD-230357. PMID: 38217613Free PMC Article
Begemann MJ, Brand BA, Ćurčić-Blake B, Aleman A, Sommer IE
Psychol Med 2020 Nov;50(15):2465-2486. Epub 2020 Oct 19 doi: 10.1017/S0033291720003670. PMID: 33070785Free PMC Article
Garg RK, Mahadevan A, Malhotra HS, Rizvi I, Kumar N, Uniyal R
Rev Med Virol 2019 Sep;29(5):e2058. Epub 2019 Jun 24 doi: 10.1002/rmv.2058. PMID: 31237061
Liu JF, Li JX
Acta Pharmacol Sin 2018 Dec;39(12):1823-1829. Epub 2018 Oct 31 doi: 10.1038/s41401-018-0180-x. PMID: 30382181Free PMC Article

Prognosis

Klein P, Kaminski RM, Koepp M, Löscher W
Nat Rev Drug Discov 2024 Sep;23(9):682-708. Epub 2024 Jul 22 doi: 10.1038/s41573-024-00981-w. PMID: 39039153
Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT
Nat Rev Dis Primers 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y. PMID: 33986301Free PMC Article
Bastos F, Cross JH
Handb Clin Neurol 2020;174:137-158. doi: 10.1016/B978-0-444-64148-9.00011-9. PMID: 32977874
Mewasingh LD, Chin RFM, Scott RC
Dev Med Child Neurol 2020 Nov;62(11):1245-1249. Epub 2020 Aug 3 doi: 10.1111/dmcn.14642. PMID: 32748466
Garg RK, Mahadevan A, Malhotra HS, Rizvi I, Kumar N, Uniyal R
Rev Med Virol 2019 Sep;29(5):e2058. Epub 2019 Jun 24 doi: 10.1002/rmv.2058. PMID: 31237061

Clinical prediction guides

Klein P, Kaminski RM, Koepp M, Löscher W
Nat Rev Drug Discov 2024 Sep;23(9):682-708. Epub 2024 Jul 22 doi: 10.1038/s41573-024-00981-w. PMID: 39039153
Rodríguez-Palmero A, Boerrigter MM, Gómez-Andrés D, Aldinger KA, Marcos-Alcalde Í, Popp B, Everman DB, Lovgren AK, Arpin S, Bahrambeigi V, Beunders G, Bisgaard AM, Bjerregaard VA, Bruel AL, Challman TD, Cogné B, Coubes C, de Man SA, Denommé-Pichon AS, Dye TJ, Elmslie F, Feuk L, García-Miñaúr S, Gertler T, Giorgio E, Gruchy N, Haack TB, Haldeman-Englert CR, Haukanes BI, Hoyer J, Hurst ACE, Isidor B, Soller MJ, Kushary S, Kvarnung M, Landau YE, Leppig KA, Lindstrand A, Kleinendorst L, MacKenzie A, Mandrile G, Mendelsohn BA, Moghadasi S, Morton JE, Moutton S, Müller AJ, O'Leary M, Pacio-Míguez M, Palomares-Bralo M, Parikh S, Pfundt R, Pode-Shakked B, Rauch A, Repnikova E, Revah-Politi A, Ross MJ, Ruivenkamp CAL, Sarrazin E, Savatt JM, Schlüter A, Schönewolf-Greulich B, Shad Z, Shaw-Smith C, Shieh JT, Shohat M, Spranger S, Thiese H, Mau-Them FT, van Bon B, van de Burgt I, van de Laar IMBH, van Drie E, van Haelst MM, van Ravenswaaij-Arts CM, Verdura E, Vitobello A, Waldmüller S, Whiting S, Zweier C, Prada CE, de Vries BBA, Dobyns WB, Reiter SF, Gómez-Puertas P, Pujol A, Tümer Z
Genet Med 2021 May;23(5):888-899. Epub 2021 Feb 17 doi: 10.1038/s41436-020-01075-9. PMID: 33597769
Begemann MJ, Brand BA, Ćurčić-Blake B, Aleman A, Sommer IE
Psychol Med 2020 Nov;50(15):2465-2486. Epub 2020 Oct 19 doi: 10.1017/S0033291720003670. PMID: 33070785Free PMC Article
Mewasingh LD, Chin RFM, Scott RC
Dev Med Child Neurol 2020 Nov;62(11):1245-1249. Epub 2020 Aug 3 doi: 10.1111/dmcn.14642. PMID: 32748466
Huang R, Wang K, Hu J
Nutrients 2016 Aug 6;8(8) doi: 10.3390/nu8080483. PMID: 27509521Free PMC Article

Recent systematic reviews

Occhipinti C, La Russa R, Iacoponi N, Lazzari J, Costantino A, Di Fazio N, Del Duca F, Maiese A, Fineschi V
Int J Mol Sci 2023 Dec 4;24(23) doi: 10.3390/ijms242317122. PMID: 38069445Free PMC Article
Amoretti S, Rabelo-da-Ponte FD, Garriga M, Forte MF, Penadés R, Vieta E, Parellada E, Ramos-Quiroga JA, Gama CS, Verdolini N, Bitanihirwe B, Garcia-Rizo C
Psychol Med 2022 Oct;52(14):2874-2884. Epub 2022 Aug 18 doi: 10.1017/S0033291722002409. PMID: 35979824
Gowen AM, Odegaard KE, Hernandez J, Chand S, Koul S, Pendyala G, Yelamanchili SV
Wiley Interdiscip Rev RNA 2021 May;12(3):e1637. Epub 2020 Dec 17 doi: 10.1002/wrna.1637. PMID: 33336550Free PMC Article
Huang R, Wang K, Hu J
Nutrients 2016 Aug 6;8(8) doi: 10.3390/nu8080483. PMID: 27509521Free PMC Article
Lu D, Song H, Hao Z, Wu T, McCleery J
Cochrane Database Syst Rev 2011 Dec 7;(12):CD002955. doi: 10.1002/14651858.CD002955.pub4. PMID: 22161372

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