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Benign neoplasm of brain

MedGen UID:
99225
Concept ID:
C0496899
Neoplastic Process
Synonyms: Benign Brain Neoplasm; Benign Brain Neoplasms; Benign Neoplasm, Brain; Benign Neoplasms, Brain; Brain Benign Neoplasm; Brain Benign Neoplasms; Brain Neoplasm, Benign; Brain Neoplasms, Benign; Neoplasms, Brain, Benign
SNOMED CT: Benign brain tumor (92030004); Benign neoplasm of brain (92030004)
 
Monarch Initiative: MONDO:0021451

Definition

A neoplasm that arises from the brain and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

McKinnon C, Nandhabalan M, Murray SA, Plaha P
BMJ 2021 Jul 14;374:n1560. doi: 10.1136/bmj.n1560. PMID: 34261630
Perkins A, Liu G
Am Fam Physician 2016 Feb 1;93(3):211-7. PMID: 26926614
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
J Clin Endocrinol Metab 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991

Recent clinical studies

Etiology

Ganz JC
Prog Brain Res 2022;268(1):229-258. Epub 2022 Jan 13 doi: 10.1016/bs.pbr.2021.10.034. PMID: 35074082
Lapointe S, Perry A, Butowski NA
Lancet 2018 Aug 4;392(10145):432-446. Epub 2018 Jul 27 doi: 10.1016/S0140-6736(18)30990-5. PMID: 30060998
McNeill KA
Neurol Clin 2016 Nov;34(4):981-998. doi: 10.1016/j.ncl.2016.06.014. PMID: 27720005
Perkins A, Liu G
Am Fam Physician 2016 Feb 1;93(3):211-7. PMID: 26926614
Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

Diagnosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Partap S, Monje M
Continuum (Minneap Minn) 2020 Dec;26(6):1553-1583. doi: 10.1212/CON.0000000000000955. PMID: 33273172
Perkins A, Liu G
Am Fam Physician 2016 Feb 1;93(3):211-7. PMID: 26926614
Gállego Pérez-Larraya J, Hildebrand J
Handb Clin Neurol 2014;121:1143-57. doi: 10.1016/B978-0-7020-4088-7.00077-8. PMID: 24365409
Herholz K, Langen KJ, Schiepers C, Mountz JM
Semin Nucl Med 2012 Nov;42(6):356-70. doi: 10.1053/j.semnuclmed.2012.06.001. PMID: 23026359Free PMC Article

Therapy

Rominiyi O, Vanderlinden A, Clenton SJ, Bridgewater C, Al-Tamimi Y, Collis SJ
Br J Cancer 2021 Feb;124(4):697-709. Epub 2020 Nov 4 doi: 10.1038/s41416-020-01136-5. PMID: 33144698Free PMC Article
Hollon TC, Pandian B, Adapa AR, Urias E, Save AV, Khalsa SSS, Eichberg DG, D'Amico RS, Farooq ZU, Lewis S, Petridis PD, Marie T, Shah AH, Garton HJL, Maher CO, Heth JA, McKean EL, Sullivan SE, Hervey-Jumper SL, Patil PG, Thompson BG, Sagher O, McKhann GM 2nd, Komotar RJ, Ivan ME, Snuderl M, Otten ML, Johnson TD, Sisti MB, Bruce JN, Muraszko KM, Trautman J, Freudiger CW, Canoll P, Lee H, Camelo-Piragua S, Orringer DA
Nat Med 2020 Jan;26(1):52-58. Epub 2020 Jan 6 doi: 10.1038/s41591-019-0715-9. PMID: 31907460Free PMC Article
Lima Fde M, Carvalho AL, Silva JC Jr, Amorim R, Dellaretti M, Wendling-Henriques LA, Maldaun M, Kirchhoff D, Botelho RV; Sociedade Brasileira de Neurocirurgia
Rev Assoc Med Bras (1992) 2016 Sep-Oct;62(5):389-94. doi: 10.1590/1806-9282.62.05.389. PMID: 27656846
Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group
Lancet Oncol 2015 Jun;16(6):e270-8. Epub 2015 May 27 doi: 10.1016/S1470-2045(15)70057-4. PMID: 26065612
Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B
N Engl J Med 1990 Feb 22;322(8):494-500. doi: 10.1056/NEJM199002223220802. PMID: 2405271

Prognosis

Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2019 Nov 1;21(Suppl 5):v1-v100. doi: 10.1093/neuonc/noz150. PMID: 31675094Free PMC Article
Witthayanuwat S, Pesee M, Supaadirek C, Supakalin N, Thamronganantasakul K, Krusun S
Asian Pac J Cancer Prev 2018 Sep 26;19(9):2613-2617. doi: 10.22034/APJCP.2018.19.9.2613. PMID: 30256068Free PMC Article
Barnholtz-Sloan JS, Ostrom QT, Cote D
Neurol Clin 2018 Aug;36(3):395-419. Epub 2018 Jun 15 doi: 10.1016/j.ncl.2018.04.001. PMID: 30072062
Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P, Settle S, Prabhu SS, Lang FF, Levine N, McGovern S, Sulman E, McCutcheon IE, Azeem S, Cahill D, Tatsui C, Heimberger AB, Ferguson S, Ghia A, Demonte F, Raza S, Guha-Thakurta N, Yang J, Sawaya R, Hess KR, Rao G
Lancet Oncol 2017 Aug;18(8):1040-1048. Epub 2017 Jul 4 doi: 10.1016/S1470-2045(17)30414-X. PMID: 28687375Free PMC Article
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article

Clinical prediction guides

Li G, Wu F, Zeng F, Zhai Y, Feng Y, Chang Y, Wang D, Jiang T, Zhang W
CNS Neurosci Ther 2021 Feb;27(2):186-195. Epub 2020 Oct 16 doi: 10.1111/cns.13464. PMID: 33063446Free PMC Article
Suh JH, Kotecha R, Chao ST, Ahluwalia MS, Sahgal A, Chang EL
Nat Rev Clin Oncol 2020 May;17(5):279-299. Epub 2020 Feb 20 doi: 10.1038/s41571-019-0320-3. PMID: 32080373
Davis ME
Semin Oncol Nurs 2018 Dec;34(5):420-429. Epub 2018 Nov 2 doi: 10.1016/j.soncn.2018.10.001. PMID: 30392758
Tsitsia V, Svolou P, Kapsalaki E, Theodorou K, Vassiou K, Valotassiou V, Georgoulias P, Fezoulidis I, Tsougos I
Hell J Nucl Med 2017 Jan-Apr;20(1):57-61. PMID: 28426840
Neagu MR, Gill CM, Batchelor TT, Brastianos PK
Chin Clin Oncol 2015 Jun;4(2):22. doi: 10.3978/j.issn.2304-3865.2015.06.04. PMID: 26112808

Recent systematic reviews

Li Y, Liu Y, Liang Y, Wei R, Zhang W, Yao W, Luo S, Pang X, Wang Y, Jiang X, Lai S, Yang R
Eur Radiol 2022 Nov;32(11):8039-8051. Epub 2022 May 19 doi: 10.1007/s00330-022-08828-x. PMID: 35587827
Dar N, Mantziaris G, Pikis S, Young L, Sheehan J
World Neurosurg 2022 Aug;164:160-166. Epub 2022 May 10 doi: 10.1016/j.wneu.2022.04.136. PMID: 35552031
Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tomé WA, Wang TJC, Zimmer AS, Ziu M, Brown PD
Pract Radiat Oncol 2022 Jul-Aug;12(4):265-282. Epub 2022 May 6 doi: 10.1016/j.prro.2022.02.003. PMID: 35534352
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Rosenfelder N, Khoo V
BMJ Clin Evid 2011 Jul 26;2011 PMID: 21791125Free PMC Article

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