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Complex partial epilepsy

MedGen UID:
43169
Concept ID:
C0085417
Disease or Syndrome
Synonyms: Complex Partial Epilepsy; Complex Partial Seizure Disorder; Disorder, Complex Partial Seizures; Epilepsy, Complex Partial; Epilepsy, Psychic Equivalent; Epilepsy, Psychomotor; Partial Epilepsy, Complex; Psychic Equivalent Epilepsy; Psychomotor Epilepsy; Seizure Disorder, Complex Partial
SNOMED CT: Psychomotor epilepsy (361123003)
 
Monarch Initiative: MONDO:0006710

Definition

A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and automatism may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8) [from MONDO]

Professional guidelines

PubMed

Ellens NR, Elisevich K, Burdette DE, Patra SE
Stereotact Funct Neurosurg 2018;96(4):259-263. Epub 2018 Aug 27 doi: 10.1159/000492232. PMID: 30149389
Sporis D, Bozina N, Basić S, Lovrić M, Babić T, Susak I, Marković I
Coll Antropol 2013 Mar;37(1):41-5. PMID: 23697249
Reiter JM, Andrews DJ
Seizure 2000 Apr;9(3):198-203. doi: 10.1053/seiz.1999.0374. PMID: 10775516

Curated

UK NICE Guideline NG217, Epilepsies in children, young people and adults, 2022

Recent clinical studies

Etiology

Pavlidou E, Hagel C, Panteliadis C
Childs Nerv Syst 2013 Nov;29(11):2011-7. Epub 2013 Jul 12 doi: 10.1007/s00381-013-2224-3. PMID: 23846392
Gorham R, Persinger MA
Epilepsy Behav 2012 Feb;23(2):152-8. Epub 2011 Dec 27 doi: 10.1016/j.yebeh.2011.11.010. PMID: 22206825
Willmore LJ, Abelson MB, Ben-Menachem E, Pellock JM, Shields WD
Epilepsia 2009 Feb;50(2):163-73. doi: 10.1111/j.1528-1167.2008.01988.x. PMID: 19230067
Saka E, Saygi S, Ciğer A, Selekler K
Seizure 1996 Dec;5(4):299-302. doi: 10.1016/s1059-1311(96)80024-0. PMID: 8952016
Luciano D, Devinsky O, Perrine K
Neurology 1993 Oct;43(10):2113-7. doi: 10.1212/wnl.43.10.2113. PMID: 8413975

Diagnosis

Greenlee BA, Ferrell RB, Kauffman CI, McAllister TW
Curr Psychiatry Rep 2003 Oct;5(5):410-6. doi: 10.1007/s11920-003-0076-3. PMID: 13678563
Blume WT
Adv Exp Med Biol 2002;497:9-18. PMID: 11993744
Saka E, Saygi S, Ciğer A, Selekler K
Seizure 1996 Dec;5(4):299-302. doi: 10.1016/s1059-1311(96)80024-0. PMID: 8952016
Duncan JS
Epilepsia 1996 Jul;37(7):598-605. doi: 10.1111/j.1528-1157.1996.tb00622.x. PMID: 8681890
Cascino GD
Psychiatr Clin North Am 1992 Jun;15(2):373-82. PMID: 1603730

Therapy

Greenlee BA, Ferrell RB, Kauffman CI, McAllister TW
Curr Psychiatry Rep 2003 Oct;5(5):410-6. doi: 10.1007/s11920-003-0076-3. PMID: 13678563
Mengel H
Epilepsia 1994;35 Suppl 5:S81-4. doi: 10.1111/j.1528-1157.1994.tb05976.x. PMID: 8039477
Fromm GH
Epilepsia 1994;35 Suppl 5:S77-80. doi: 10.1111/j.1528-1157.1994.tb05975.x. PMID: 8039476
Connelly JF
Ann Pharmacother 1993 Feb;27(2):197-204. doi: 10.1177/106002809302700215. PMID: 8439699
Robertson PL, Garofalo EA, Silverstein FS, Komarynski MA
Epilepsia 1993 Sep-Oct;34(5):965-8. doi: 10.1111/j.1528-1157.1993.tb02119.x. PMID: 8404753

Prognosis

Pavlidou E, Hagel C, Panteliadis C
Childs Nerv Syst 2013 Nov;29(11):2011-7. Epub 2013 Jul 12 doi: 10.1007/s00381-013-2224-3. PMID: 23846392
MacDonald DA, Holland D
Psychol Rep 2002 Dec;91(3 Pt 1):785-92. doi: 10.2466/pr0.2002.91.3.785. PMID: 12530725
Saka E, Saygi S, Ciğer A, Selekler K
Seizure 1996 Dec;5(4):299-302. doi: 10.1016/s1059-1311(96)80024-0. PMID: 8952016
Cascino GD
Epilepsia 1993;34 Suppl 1:S21-8. doi: 10.1111/j.1528-1157.1993.tb05903.x. PMID: 8462490
Keränen T, Riekkinen P
Acta Neurol Scand Suppl 1988;117:7-14. doi: 10.1111/j.1600-0404.1988.tb07997.x. PMID: 3051864

Clinical prediction guides

Pavlidou E, Hagel C, Panteliadis C
Childs Nerv Syst 2013 Nov;29(11):2011-7. Epub 2013 Jul 12 doi: 10.1007/s00381-013-2224-3. PMID: 23846392
Gorham R, Persinger MA
Epilepsy Behav 2012 Feb;23(2):152-8. Epub 2011 Dec 27 doi: 10.1016/j.yebeh.2011.11.010. PMID: 22206825
Willmore LJ, Abelson MB, Ben-Menachem E, Pellock JM, Shields WD
Epilepsia 2009 Feb;50(2):163-73. doi: 10.1111/j.1528-1167.2008.01988.x. PMID: 19230067
MacDonald DA, Holland D
Psychol Rep 2002 Dec;91(3 Pt 1):785-92. doi: 10.2466/pr0.2002.91.3.785. PMID: 12530725
Keränen T, Riekkinen P
Acta Neurol Scand Suppl 1988;117:7-14. doi: 10.1111/j.1600-0404.1988.tb07997.x. PMID: 3051864

Recent systematic reviews

Gamble C, Williamson PR, Chadwick DW, Marson AG
Neurology 2006 May 9;66(9):1310-7. doi: 10.1212/01.wnl.0000210517.03902.6e. PMID: 16682660

Supplemental Content

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    Clinical resources

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    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2022
      UK NICE Guideline NG217, Epilepsies in children, young people and adults, 2022

    Consumer resources

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