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Reflex epilepsy

MedGen UID:
75726
Concept ID:
C0270857
Disease or Syndrome
Synonyms: Epilepsies, Reflex; Epilepsy, Reflex; Reflex Epilepsies; Reflex Epilepsy
SNOMED CT: Sensory-induced epilepsy (79745005); Epilepsy associated with specific stimuli (79745005); Reflex epilepsy (79745005)
 
Monarch Initiative: MONDO:0017768
Orphanet: ORPHA310

Definition

Reflex epilepsy refers to epilepsies where recurrent seizures are provoked by a clearly defined extrinsic (most commonly) or intrinsic triggering stimuli such as flashing lights (photosensitive epilepsy), startling noises (startle epilepsy), urinating (micturition induced seizures), exposure to hot-water (hot water epilepsy, see these terms), eating, reading, and thinking, while being associated with an enduring abnormal predisposition to have such seizures (thereby meeting the conceptual definition of epilepsy). [from ORDO]

Professional guidelines

PubMed

Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Tan ZR, Tian FF, Long XY, Zhang C, Feng YY, Zhang SY, Li GL
Epilepsy Behav 2018 Sep;86:163-165. Epub 2018 Jul 20 doi: 10.1016/j.yebeh.2018.04.030. PMID: 30037584
Zeki G, Ilker IH, Hidir UU, Zeki O
Neurologist 2010 Mar;16(2):109-12. doi: 10.1097/NRL.0b013e3181bd603c. PMID: 20220445

Recent clinical studies

Therapy

Li CMF, Kim DD, Mirsattari SM
JAMA Neurol 2024 Aug 1;81(8):882-883. doi: 10.1001/jamaneurol.2024.0884. PMID: 38648046
Geenen KR, Patel S, Thiele EA
Dev Med Child Neurol 2021 Mar;63(3):259-262. Epub 2020 Oct 31 doi: 10.1111/dmcn.14723. PMID: 33135153
Padmanaban V, Inati S, Ksendzovsky A, Zaghloul K
Brain Res 2019 Jan 15;1703:18-25. Epub 2018 Aug 1 doi: 10.1016/j.brainres.2018.07.025. PMID: 30076791
Stern J
Handb Clin Neurol 2015;129:469-77. doi: 10.1016/B978-0-444-62630-1.00026-3. PMID: 25726285
Harding GF, Takahashi T
Epilepsia 2004;45 Suppl 1:46-7. doi: 10.1111/j.0013-9580.2004.451007.x. PMID: 14706046

Prognosis

Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
Padmanaban V, Inati S, Ksendzovsky A, Zaghloul K
Brain Res 2019 Jan 15;1703:18-25. Epub 2018 Aug 1 doi: 10.1016/j.brainres.2018.07.025. PMID: 30076791
Turco EC, Andreolli A, Pisani F
Seizure 2018 Jul;59:11-15. Epub 2018 Apr 23 doi: 10.1016/j.seizure.2018.04.013. PMID: 29727740
Xu L, Guo D, Liu YY, Qiao DD, Ye JY, Xue R
Epilepsy Behav 2018 Mar;80:326-330. Epub 2018 Jan 19 doi: 10.1016/j.yebeh.2017.11.008. PMID: 29358100
Verrotti A, Trotta D, Salladini C, di Corcia G, Chiarelli F
J Child Neurol 2004 Aug;19(8):571-8. doi: 10.1177/088307380401900802. PMID: 15605465

Clinical prediction guides

Voinescu PE, Kelly M, French JA, Harden C, Davis A, Lau C, Ehlert A, Allien S, Osterhaus E, Barnard S, Jain R, Pennell PB
Epilepsia 2023 Sep;64(9):e194-e199. Epub 2023 Jul 25 doi: 10.1111/epi.17718. PMID: 37452790
Padmanaban V, Inati S, Ksendzovsky A, Zaghloul K
Brain Res 2019 Jan 15;1703:18-25. Epub 2018 Aug 1 doi: 10.1016/j.brainres.2018.07.025. PMID: 30076791
Martins da Silva A, Leal B
Seizure 2017 Aug;50:209-218. Epub 2017 Apr 5 doi: 10.1016/j.seizure.2017.04.001. PMID: 28532712
Brigo F, Rossini F, Stefani A, Nardone R, Tezzon F, Fiaschi A, Manganotti P, Bongiovanni LG
Clin Neurophysiol 2013 Feb;124(2):221-7. Epub 2012 Aug 24 doi: 10.1016/j.clinph.2012.07.017. PMID: 22925838
Avanzini G
Ann N Y Acad Sci 2003 Nov;999:95-102. doi: 10.1196/annals.1284.008. PMID: 14681120

Recent systematic reviews

Puteikis K, Mameniškienė R, Wolf P
Epilepsy Behav 2023 Aug;145:109346. Epub 2023 Jul 10 doi: 10.1016/j.yebeh.2023.109346. PMID: 37437391
Nucera B, Rinaldi F, Dono F, Lanzone J, Evangelista G, Consoli S, Tappatà M, Narducci F, Troisi S, Trinka E, Brigo F
Seizure 2023 Jul;109:52-59. Epub 2023 May 5 doi: 10.1016/j.seizure.2023.05.004. PMID: 37229848
Girges C, Vijiaratnam N, Wirth T, Tjoakarfa C, Idaszak J, Seneviratne U
Seizure 2020 Dec;83:21-31. Epub 2020 Sep 23 doi: 10.1016/j.seizure.2020.09.013. PMID: 33080481
Randhawa J, Hrazdil CT, Hassan I
Epilepsy Behav 2019 Mar;92:18-25. Epub 2018 Dec 31 doi: 10.1016/j.yebeh.2018.10.036. PMID: 30599458
Illingworth JL, Ring H
Epilepsia 2013 Dec;54(12):2036-47. Epub 2013 Aug 27 doi: 10.1111/epi.12340. PMID: 24032405

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