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Digestive system neoplasm

MedGen UID:
8398
•Concept ID:
C0012243
•
Neoplastic Process
Synonyms: Digestive System Neoplasm; Digestive System Neoplasms; Neoplasm, Digestive System; Neoplasms, Digestive System
SNOMED CT: Neoplasm of digestive system (128348002); Neoplasm of digestive tract (128415001)
 
HPO: HP:0034930

Definition

A tumor (abnormal growth of tissue) of the digestive system. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDigestive system neoplasm

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Advances in screening and detection of gastric cancer.
Xia JY, Aadam AA
J Surg Oncol 2022 Jun;125(7):1104-1109. doi: 10.1002/jso.26844. PMID: 35481909Free PMC Article
Pancreatic Cancer: Pathogenesis, Screening, Diagnosis, and Treatment.
Wood LD, Canto MI, Jaffee EM, Simeone DM
Gastroenterology 2022 Aug;163(2):386-402.e1. Epub 2022 Apr 7 doi: 10.1053/j.gastro.2022.03.056. PMID: 35398344Free PMC Article

Recent clinical studies

Etiology

Cholelithiasis increased prostate cancer risk: evidence from a case-control study and a meta-analysis.
Li YD, Ren ZJ, Gao L, Ma JH, Gou YQ, Tan W, Liu C
BMC Urol 2022 Oct 3;22(1):160. doi: 10.1186/s12894-022-01110-8. PMID: 36192737Free PMC Article
One-year mortality and consequences of COVID-19 in cancer patients: A cohort study.
Chai C, Feng X, Lu M, Li S, Chen K, Wang H, Wang W, Tang Z, Cheng G, Wu X, Li Y, Wen Y, Da B, Fan H, Wang L, Ai F, Li W, Peng C, Zhang H, Wen S, Zhang J, Weng Y, Tang Z
IUBMB Life 2021 Oct;73(10):1244-1256. Epub 2021 Aug 29 doi: 10.1002/iub.2536. PMID: 34318585Free PMC Article
Occupational exposures and odds of gastric cancer: a StoP project consortium pooled analysis.
Shah SC, Boffetta P, Johnson KC, Hu J, Palli D, Ferraroni M, Tsugane S, Hamada GS, Hidaka A, Zaridze D, Maximovich D, Vioque J, Navarrete-Munoz EM, Zhang ZF, Mu L, Boccia S, Pastorino R, Kurtz RC, Rota M, Bonzi R, Negri E, La Vecchia C, Pelucchi C, Hashim D
Int J Epidemiol 2020 Apr 1;49(2):422-434. doi: 10.1093/ije/dyz263. PMID: 31965145Free PMC Article
Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H
J Cell Physiol 2020 Apr;235(4):3438-3446. Epub 2019 Oct 16 doi: 10.1002/jcp.29233. PMID: 31621076
Associations between calcium and magnesium intake and the risk of incident gastric cancer: A prospective cohort analysis of the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study.
Shah SC, Dai Q, Zhu X, Peek RM Jr, Smalley W, Roumie C, Shrubsole MJ
Int J Cancer 2020 Jun 1;146(11):2999-3010. Epub 2019 Oct 12 doi: 10.1002/ijc.32659. PMID: 31472027Free PMC Article

Diagnosis

Cholelithiasis increased prostate cancer risk: evidence from a case-control study and a meta-analysis.
Li YD, Ren ZJ, Gao L, Ma JH, Gou YQ, Tan W, Liu C
BMC Urol 2022 Oct 3;22(1):160. doi: 10.1186/s12894-022-01110-8. PMID: 36192737Free PMC Article
Prognostic value of CSN5 in patients with digestive system cancers: a systematic review and meta-analysis.
Guo Y, Gao M, Yao Y, Li J, Chen X, Wang X, Chen Z, Yuan Y, Ma W
BMC Cancer 2022 Jul 23;22(1):812. doi: 10.1186/s12885-022-09867-9. PMID: 35870903Free PMC Article
Heterozygous missense mutation of the RELN gene is one of the causes of epilepsy.
Fang XQ, Zhang RR, Liu XW
Neurol Res 2022 Mar;44(3):262-267. Epub 2021 Sep 27 doi: 10.1080/01616412.2021.1979748. PMID: 34569441
Pancreatic carcinoma underlying a complex presentation in late pregnancy: a case report.
Shi AW, Shen XF, Ding HJ, Liu YQ, Meng L, Kalionis B
J Med Case Rep 2018 Dec 15;12(1):369. doi: 10.1186/s13256-018-1911-9. PMID: 30551739Free PMC Article
A Meta-Analysis of the Diagnostic Accuracy of Circular RNAs in Digestive System Malignancy.
Chen Z, Zhang L, Han G, Zuo X, Zhang Y, Zhu Q, Wu J, Wang X
Cell Physiol Biochem 2018;45(3):962-972. Epub 2018 Feb 2 doi: 10.1159/000487291. PMID: 29428945

Therapy

Cholelithiasis increased prostate cancer risk: evidence from a case-control study and a meta-analysis.
Li YD, Ren ZJ, Gao L, Ma JH, Gou YQ, Tan W, Liu C
BMC Urol 2022 Oct 3;22(1):160. doi: 10.1186/s12894-022-01110-8. PMID: 36192737Free PMC Article
Intake of artificial sweeteners among adults is associated with reduced odds of gastrointestinal luminal cancers: a meta-analysis of cohort and case-control studies.
Tepler A, Hoffman G, Jindal S, Narula N, Shah SC
Nutr Res 2021 Sep;93:87-98. Epub 2021 Aug 1 doi: 10.1016/j.nutres.2021.07.007. PMID: 34461350Free PMC Article
Occupational exposures and odds of gastric cancer: a StoP project consortium pooled analysis.
Shah SC, Boffetta P, Johnson KC, Hu J, Palli D, Ferraroni M, Tsugane S, Hamada GS, Hidaka A, Zaridze D, Maximovich D, Vioque J, Navarrete-Munoz EM, Zhang ZF, Mu L, Boccia S, Pastorino R, Kurtz RC, Rota M, Bonzi R, Negri E, La Vecchia C, Pelucchi C, Hashim D
Int J Epidemiol 2020 Apr 1;49(2):422-434. doi: 10.1093/ije/dyz263. PMID: 31965145Free PMC Article
Multiple myeloma with onset of pancreas involvement: A case report.
Wang X, Xie H, Zhang L
Medicine (Baltimore) 2019 Jul;98(30):e16567. doi: 10.1097/MD.0000000000016567. PMID: 31348284Free PMC Article
CD133 overexpression correlates with clinicopathological features of gastric cancer patients and its impact on survival: a systematic review and meta-analysis.
Yiming L, Yunshan G, Bo M, Yu Z, Tao W, Gengfang L, Dexian F, Shiqian C, Jianli J, Juan T, Zhinan C
Oncotarget 2015 Dec 8;6(39):42019-27. doi: 10.18632/oncotarget.5714. PMID: 26503471Free PMC Article

Prognosis

Prognostic value of CSN5 in patients with digestive system cancers: a systematic review and meta-analysis.
Guo Y, Gao M, Yao Y, Li J, Chen X, Wang X, Chen Z, Yuan Y, Ma W
BMC Cancer 2022 Jul 23;22(1):812. doi: 10.1186/s12885-022-09867-9. PMID: 35870903Free PMC Article
One-year mortality and consequences of COVID-19 in cancer patients: A cohort study.
Chai C, Feng X, Lu M, Li S, Chen K, Wang H, Wang W, Tang Z, Cheng G, Wu X, Li Y, Wen Y, Da B, Fan H, Wang L, Ai F, Li W, Peng C, Zhang H, Wen S, Zhang J, Weng Y, Tang Z
IUBMB Life 2021 Oct;73(10):1244-1256. Epub 2021 Aug 29 doi: 10.1002/iub.2536. PMID: 34318585Free PMC Article
Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H
J Cell Physiol 2020 Apr;235(4):3438-3446. Epub 2019 Oct 16 doi: 10.1002/jcp.29233. PMID: 31621076
CD133 overexpression correlates with clinicopathological features of gastric cancer patients and its impact on survival: a systematic review and meta-analysis.
Yiming L, Yunshan G, Bo M, Yu Z, Tao W, Gengfang L, Dexian F, Shiqian C, Jianli J, Juan T, Zhinan C
Oncotarget 2015 Dec 8;6(39):42019-27. doi: 10.18632/oncotarget.5714. PMID: 26503471Free PMC Article
Cancer risks and long-term community-level exposure to pentachlorophenol in contaminated areas, China.
Cheng P, Zhang Q, Shan X, Shen D, Wang B, Tang Z, Jin Y, Zhang C, Huang F
Environ Sci Pollut Res Int 2015 Jan;22(2):1309-17. Epub 2014 Aug 21 doi: 10.1007/s11356-014-3469-4. PMID: 25138560

Clinical prediction guides

Prognostic value of CSN5 in patients with digestive system cancers: a systematic review and meta-analysis.
Guo Y, Gao M, Yao Y, Li J, Chen X, Wang X, Chen Z, Yuan Y, Ma W
BMC Cancer 2022 Jul 23;22(1):812. doi: 10.1186/s12885-022-09867-9. PMID: 35870903Free PMC Article
Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H
J Cell Physiol 2020 Apr;235(4):3438-3446. Epub 2019 Oct 16 doi: 10.1002/jcp.29233. PMID: 31621076
Associations between calcium and magnesium intake and the risk of incident gastric cancer: A prospective cohort analysis of the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study.
Shah SC, Dai Q, Zhu X, Peek RM Jr, Smalley W, Roumie C, Shrubsole MJ
Int J Cancer 2020 Jun 1;146(11):2999-3010. Epub 2019 Oct 12 doi: 10.1002/ijc.32659. PMID: 31472027Free PMC Article
Pancreatic carcinoma underlying a complex presentation in late pregnancy: a case report.
Shi AW, Shen XF, Ding HJ, Liu YQ, Meng L, Kalionis B
J Med Case Rep 2018 Dec 15;12(1):369. doi: 10.1186/s13256-018-1911-9. PMID: 30551739Free PMC Article

Recent systematic reviews

Prognostic value of CSN5 in patients with digestive system cancers: a systematic review and meta-analysis.
Guo Y, Gao M, Yao Y, Li J, Chen X, Wang X, Chen Z, Yuan Y, Ma W
BMC Cancer 2022 Jul 23;22(1):812. doi: 10.1186/s12885-022-09867-9. PMID: 35870903Free PMC Article
Intake of artificial sweeteners among adults is associated with reduced odds of gastrointestinal luminal cancers: a meta-analysis of cohort and case-control studies.
Tepler A, Hoffman G, Jindal S, Narula N, Shah SC
Nutr Res 2021 Sep;93:87-98. Epub 2021 Aug 1 doi: 10.1016/j.nutres.2021.07.007. PMID: 34461350Free PMC Article
CD133 overexpression correlates with clinicopathological features of gastric cancer patients and its impact on survival: a systematic review and meta-analysis.
Yiming L, Yunshan G, Bo M, Yu Z, Tao W, Gengfang L, Dexian F, Shiqian C, Jianli J, Juan T, Zhinan C
Oncotarget 2015 Dec 8;6(39):42019-27. doi: 10.18632/oncotarget.5714. PMID: 26503471Free PMC Article

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