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Parotid gland neoplasm

MedGen UID:
18313
•Concept ID:
C0030581
•
Neoplastic Process
Synonyms: Neoplasm, Parotid; Neoplasms, Parotid; Parotid Neoplasm; Parotid Neoplasms
SNOMED CT: Neoplasm of parotid gland (126788000); Tumor of parotid gland (126788000)
 
Monarch Initiative: MONDO:0021243

Definition

A benign or malignant neoplasm that affects the parotid gland. Representative examples of benign neoplasms include Warthin tumor, monomorphic adenoma, and pleomorphic adenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. [from NCI]

Professional guidelines

PubMed

Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment.
Nakaguro M, Tada Y, Faquin WC, Sadow PM, Wirth LJ, Nagao T
Cancer Cytopathol 2020 Oct;128(10):693-703. Epub 2020 May 18 doi: 10.1002/cncy.22288. PMID: 32421944Free PMC Article
Optimal Perioperative Care in Major Head and Neck Cancer Surgery With Free Flap Reconstruction: A Consensus Review and Recommendations From the Enhanced Recovery After Surgery Society.
Dort JC, Farwell DG, Findlay M, Huber GF, Kerr P, Shea-Budgell MA, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J
JAMA Otolaryngol Head Neck Surg 2017 Mar 1;143(3):292-303. doi: 10.1001/jamaoto.2016.2981. PMID: 27737447
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Recent clinical studies

Etiology

Sebaceous Lymphadenoma: Radiology-Pathology Correlation.
Dababneh MN, Griffith CC, Patel MR, Magliocca KR
Head Neck Pathol 2021 Jun;15(2):593-598. Epub 2021 Jan 4 doi: 10.1007/s12105-020-01266-5. PMID: 33398686Free PMC Article
Parotid gland tumours in the ENT Department in Międzyleski Hospital in Warsaw between 2007 and 2014.
Dżaman K, Pietniczka-Załęska M, Piskadło-Zborowska K, Siek M, Żebrowska J
Otolaryngol Pol 2016 Feb 29;70(1):34-40. doi: 10.5604/00306657.1193068. PMID: 26926306
Warthin's tumor distribution within the parotid gland. A feasible etiologic source from lymph nodal tissue.
Colella G, Biondi P, Itro A, Compilato D, Campisi G
Minerva Stomatol 2010 May;59(5):245-9, 250-2. PMID: 20502429
Facial nerve function after parotidectomy for neoplasms with deep localization.
Marchesi M, Biffoni M, Trinchi S, Turriziani V, Campana FP
Surg Today 2006;36(4):308-11. doi: 10.1007/s00595-005-3146-9. PMID: 16554985
Basaloid salivary carcinoma.
Batsakis JG, Luna MA
Ann Otol Rhinol Laryngol 1991 Sep;100(9 Pt 1):785-7. doi: 10.1177/000348949110000918. PMID: 1952675

Diagnosis

Myopericytoma of the Parotid and Molecular Profiling: Report of a Rare Case and Review of the Literature.
Roig NJ, Wu M, Hernandez O, Liu CZ, Brandler TC
Int J Surg Pathol 2022 Aug;30(5):574-580. Epub 2021 Dec 31 doi: 10.1177/10668969211070167. PMID: 34970937
Sebaceous Lymphadenoma: Radiology-Pathology Correlation.
Dababneh MN, Griffith CC, Patel MR, Magliocca KR
Head Neck Pathol 2021 Jun;15(2):593-598. Epub 2021 Jan 4 doi: 10.1007/s12105-020-01266-5. PMID: 33398686Free PMC Article
Parotid gland tumours in the ENT Department in Międzyleski Hospital in Warsaw between 2007 and 2014.
Dżaman K, Pietniczka-Załęska M, Piskadło-Zborowska K, Siek M, Żebrowska J
Otolaryngol Pol 2016 Feb 29;70(1):34-40. doi: 10.5604/00306657.1193068. PMID: 26926306
Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms.
Matse JH, Yoshizawa J, Wang X, Elashoff D, Bolscher JG, Veerman EC, Leemans CR, Pegtel DM, Wong DT, Bloemena E
PLoS One 2015;10(11):e0142264. Epub 2015 Nov 6 doi: 10.1371/journal.pone.0142264. PMID: 26544193Free PMC Article
Basaloid salivary carcinoma.
Batsakis JG, Luna MA
Ann Otol Rhinol Laryngol 1991 Sep;100(9 Pt 1):785-7. doi: 10.1177/000348949110000918. PMID: 1952675

Therapy

Facial nerve function after parotidectomy for neoplasms with deep localization.
Marchesi M, Biffoni M, Trinchi S, Turriziani V, Campana FP
Surg Today 2006;36(4):308-11. doi: 10.1007/s00595-005-3146-9. PMID: 16554985

Prognosis

Parotid gland tumours in the ENT Department in Międzyleski Hospital in Warsaw between 2007 and 2014.
Dżaman K, Pietniczka-Załęska M, Piskadło-Zborowska K, Siek M, Żebrowska J
Otolaryngol Pol 2016 Feb 29;70(1):34-40. doi: 10.5604/00306657.1193068. PMID: 26926306
Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms.
Matse JH, Yoshizawa J, Wang X, Elashoff D, Bolscher JG, Veerman EC, Leemans CR, Pegtel DM, Wong DT, Bloemena E
PLoS One 2015;10(11):e0142264. Epub 2015 Nov 6 doi: 10.1371/journal.pone.0142264. PMID: 26544193Free PMC Article

Clinical prediction guides

Bilateral epithelial-myoepithelial carcinoma of the parotid glands.
Hattori K, Murai N, Kusano J, Takahashi Y
Head Neck 2016 Mar;38(3):E73-5. Epub 2015 Aug 28 doi: 10.1002/hed.24179. PMID: 26314935
Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms.
Matse JH, Yoshizawa J, Wang X, Elashoff D, Bolscher JG, Veerman EC, Leemans CR, Pegtel DM, Wong DT, Bloemena E
PLoS One 2015;10(11):e0142264. Epub 2015 Nov 6 doi: 10.1371/journal.pone.0142264. PMID: 26544193Free PMC Article
Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature.
Curry JL, Petruzzelli GJ, McClatchey KD, Lingen MW
Head Neck 2002 Mar;24(3):301-6. doi: 10.1002/hed.10048. PMID: 11891964

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