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Oral Cavity Benign Granular Cell Tumor

MedGen UID:: 233794
•Concept ID:: C1335117
•: Neoplastic Process

Synonym:

Oral Cavity Benign Granular Cell Neoplasm

Definition

A granular cell tumor that arises from the oral cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVOral Cavity Benign Granular Cell Tumor

Disorder by Site
- Connective and Soft Tissue Disorder
  - Connective and soft tissue neoplasm
    - Neoplasms, Muscle Tissue
      - Granular cell tumor
        Benign granular cell tumor
        Oral Cavity Benign Granular Cell Tumor
        Soft Palate Benign Granular Cell Tumor

Professional guidelines

PubMed

Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases.

Tang L, Huang LY, Cui J, Wu CR
Chin Med J (Engl) 2018 Jun 5;131(11):1321-1326. doi: 10.4103/0366-6999.232802. PMID: 29786046 Free PMC Article

Oral cavity squamous cell carcinoma: role of pretreatment imaging and its influence on management.

Arya S, Rane P, Deshmukh A
Clin Radiol 2014 Sep;69(9):916-30. Epub 2014 Jun 5 doi: 10.1016/j.crad.2014.04.013. PMID: 24908285

Medical management of fibroids.

Sankaran S, Manyonda IT
Best Pract Res Clin Obstet Gynaecol 2008 Aug;22(4):655-76. Epub 2008 May 12 doi: 10.1016/j.bpobgyn.2008.03.001. PMID: 18468953

See all (12)

Recent clinical studies

Etiology

Immunohistochemical biomarkers in oral submucous fibrosis: A scoping review.

Kavitha L, Ranganathan K, Shyam S, Fathima JHS, Umesh W, Warnakulasuriya S
J Oral Pathol Med 2022 Aug;51(7):594-602. Epub 2022 Feb 22 doi: 10.1111/jop.13280. PMID: 35102645

Inclusion bodies are not uncommon in angioleiomyoma.

Kishibe M, Igawa S, Kanno K, Matsuo R, Ishida-Yamamoto A
J Cutan Pathol 2021 Feb;48(2):269-273. Epub 2020 Oct 21 doi: 10.1111/cup.13891. PMID: 33034917

Clinical Role of Extraoral Bitter Taste Receptors.

Jeruzal-Świątecka J, Fendler W, Pietruszewska W
Int J Mol Sci 2020 Jul 21;21(14) doi: 10.3390/ijms21145156. PMID: 32708215 Free PMC Article

Primary and secondary leiomyosarcoma of the oral and perioral region--clinicopathological and immunohistochemical analysis of a rare entity with a review of the literature.

Schütz A, Smeets R, Driemel O, Hakim SG, Kosmehl H, Hanken H, Kolk A
J Oral Maxillofac Surg 2013 Jun;71(6):1132-42. Epub 2013 Feb 20 doi: 10.1016/j.joms.2012.12.011. PMID: 23434173

Medical management of fibroids.

Sankaran S, Manyonda IT
Best Pract Res Clin Obstet Gynaecol 2008 Aug;22(4):655-76. Epub 2008 May 12 doi: 10.1016/j.bpobgyn.2008.03.001. PMID: 18468953

See all (266)

Diagnosis

Utility of MUC4 in the diagnosis of secretory carcinoma of salivary glands.

Fatima S, Ahmed A, Suleman S, Din NU
Ann Diagn Pathol 2023 Dec;67:152220. Epub 2023 Oct 28 doi: 10.1016/j.anndiagpath.2023.152220. PMID: 37924657

Immunohistochemical biomarkers in oral submucous fibrosis: A scoping review.

Kavitha L, Ranganathan K, Shyam S, Fathima JHS, Umesh W, Warnakulasuriya S
J Oral Pathol Med 2022 Aug;51(7):594-602. Epub 2022 Feb 22 doi: 10.1111/jop.13280. PMID: 35102645

Oral Adult Rhabdomyoma.

da Silva Leonel ACL, Dos Santos ST, de Amorim Carvalho EJ, de Castro JFL, de Almeida OP, da Cruz Perez DE
Head Neck Pathol 2021 Dec;15(4):1253-1260. Epub 2021 Aug 10 doi: 10.1007/s12105-021-01371-z. PMID: 34378165 Free PMC Article

Granular cell tumor.

Noonan V, Lerman MA, Woo SB, Kabani S
J Mass Dent Soc 2014 Spring;63(1):45. PMID: 24941552

Congenital epulis.

Rehman MU, Khanani MF, Bekdache G, Rehman Durrani NU, Jamil A, Rahmani A, Chedid F
J Coll Physicians Surg Pak 2012 Jan;22(1):56-7. PMID: 22237195

See all (508)

Therapy

Web Axillary Pain Syndrome-Literature Evidence and Novel Rehabilitative Suggestions: A Narrative Review.

Agostini F, Attanasi C, Bernetti A, Mangone M, Paoloni M, Del Monte E, Mammucari M, Maggiori E, Russo D, Marzo RD, Migliore A, Paolucci T
Int J Environ Res Public Health 2021 Oct 2;18(19) doi: 10.3390/ijerph181910383. PMID: 34639683 Free PMC Article

Reconstruction of Mohs Defects of the Lips and Chin.

Larrabee YC, Moyer JS
Facial Plast Surg Clin North Am 2017 Aug;25(3):427-442. doi: 10.1016/j.fsc.2017.03.012. PMID: 28676167

A systematic review: perivascular epithelioid cell tumor of gastrointestinal tract.

Chen Z, Han S, Wu J, Xiong M, Huang Y, Chen J, Yuan Y, Peng J, Song W
Medicine (Baltimore) 2016 Jul;95(28):e3890. doi: 10.1097/MD.0000000000003890. PMID: 27428182 Free PMC Article

Medical management of fibroids.

Sankaran S, Manyonda IT
Best Pract Res Clin Obstet Gynaecol 2008 Aug;22(4):655-76. Epub 2008 May 12 doi: 10.1016/j.bpobgyn.2008.03.001. PMID: 18468953

Tongue strength and exercise in healthy individuals and in head and neck cancer patients.

Lazarus C
Semin Speech Lang 2006 Nov;27(4):260-7. doi: 10.1055/s-2006-955116. PMID: 17117352

See all (108)

Prognosis

Oral granular cell tumor: a collaborative clinicopathological study of 61 cases.

Aragão HHR, Lima LBR, Cavalcante IL, da Silva Neto SS, Turatti E, Cavalcante RB, Gilligan G, Panico R, de Mendonça EF, de Albuquerque-Júnior RLC, Nonaka CFW, Alves PM, de Andrade BAB, Cunha JLS
Oral Maxillofac Surg 2024 Sep;28(3):1383-1397. Epub 2024 Jun 21 doi: 10.1007/s10006-024-01272-9. PMID: 38904898

Utility of MUC4 in the diagnosis of secretory carcinoma of salivary glands.

Fatima S, Ahmed A, Suleman S, Din NU
Ann Diagn Pathol 2023 Dec;67:152220. Epub 2023 Oct 28 doi: 10.1016/j.anndiagpath.2023.152220. PMID: 37924657

Clinical Role of Extraoral Bitter Taste Receptors.

Jeruzal-Świątecka J, Fendler W, Pietruszewska W
Int J Mol Sci 2020 Jul 21;21(14) doi: 10.3390/ijms21145156. PMID: 32708215 Free PMC Article

Angiomyoma--angioleiomyoma of the cheek.

Vidaković B, Knezević AK, Manojlović S, Knezević G
Coll Antropol 2011 Mar;35(1):207-9. PMID: 21661373

Tumors of the oral cavity and pharynx.

Wertheimer-Hatch L, Hatch GF 3rd, HatchB S KF, Davis GB, Blanchard DK, Foster RS Jr, Skandalakis JE
World J Surg 2000 Apr;24(4):395-400. doi: 10.1007/s002689910064. PMID: 10706911

See all (274)

Clinical prediction guides

Oral granular cell tumor: a collaborative clinicopathological study of 61 cases.

Clinicopathological features of myofibromas and myofibromatosis affecting the oral and maxillofacial region: A systematic review.

Silveira FM, Kirschnick LB, Só BB, Schuch LF, Pereira Prado V, Sicco E, Lima RR, Bologna-Molina RE, Mosqueda-Taylor A, Vasconcelos ACU, Martins MD
J Oral Pathol Med 2024 Jul;53(6):334-340. Epub 2024 May 6 doi: 10.1111/jop.13537. PMID: 38711183

Utility of MUC4 in the diagnosis of secretory carcinoma of salivary glands.

Fatima S, Ahmed A, Suleman S, Din NU
Ann Diagn Pathol 2023 Dec;67:152220. Epub 2023 Oct 28 doi: 10.1016/j.anndiagpath.2023.152220. PMID: 37924657

Oral Adult Rhabdomyoma.

Extra-tongue oral granular cell tumor: Histological and immunohistochemical aspect.

Tobouti PL, Pigatti FM, Martins-Mussi MC, Sedassari BT, Orsini-Machado de Sousa SC
Med Oral Patol Oral Cir Bucal 2017 Jan 1;22(1):e31-e35. doi: 10.4317/medoral.21401. PMID: 27918739 Free PMC Article

See all (180)

Recent systematic reviews

Clinicopathological features of myofibromas and myofibromatosis affecting the oral and maxillofacial region: A systematic review.

Endometrial Angiogenesis of Abnormal Uterine Bleeding and Infertility in Patients with Uterine Fibroids-A Systematic Review.

Don EE, Middelkoop MA, Hehenkamp WJK, Mijatovic V, Griffioen AW, Huirne JAF
Int J Mol Sci 2023 Apr 10;24(8) doi: 10.3390/ijms24087011. PMID: 37108180 Free PMC Article

Oral granular cell tumour: A multicentric study of 56 cases and a systematic review.

Lafuente Ibáñez de Mendoza I, López Ortega K, Trierveiler M, Oliveira Alves MG, Dias Almeida J, Gándara Vila P, Aguirre Urízar JM, Pérez Sayans M
Oral Dis 2020 Apr;26(3):573-589. Epub 2020 Jan 28 doi: 10.1111/odi.13273. PMID: 31898368

Primary oral leiomyosarcoma: A systematic review and update.

Ko E
J Oral Pathol Med 2019 Oct;48(9):780-787. Epub 2019 Apr 25 doi: 10.1111/jop.12858. PMID: 30958581

A systematic review: perivascular epithelioid cell tumor of gastrointestinal tract.

Chen Z, Han S, Wu J, Xiong M, Huang Y, Chen J, Yuan Y, Peng J, Song W
Medicine (Baltimore) 2016 Jul;95(28):e3890. doi: 10.1097/MD.0000000000003890. PMID: 27428182 Free PMC Article

See all (6)

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Oral Cavity Benign Granular Cell Tumor

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

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Practice guidelines

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