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Peritoneal well differentiated papillary mesothelioma

MedGen UID:
318015
•Concept ID:
C1709507
•
Neoplastic Process
Synonyms: Peritoneal WDPM; peritoneal WDPM; Peritoneal WDPMT; Peritoneal Well Differentiated Papillary Mesothelial Tumor; peritoneal well differentiated papillary mesothelioma; Peritoneal Well-Differentiated Papillary Mesothelial Tumor
 
Monarch Initiative: MONDO:0006364

Definition

A localized or multifocal mesothelial neoplasm arising from the peritoneum. It predominantly occurs in women. It is characterized by the formation of papillae, covered by a single layer of blunt mesothelial cells. Mitotic figures are not present. There is no evidence of severe cytologic atypia. It has a relatively favorable clinical outcome, compared to diffuse malignant mesothelioma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeritoneal well differentiated papillary mesothelioma

Professional guidelines

PubMed

Adenomatoid Tumor: A Review of Pathology With Focus on Unusual Presentations and Sites, Histogenesis, Differential Diagnosis, and Molecular and Clinical Aspects With a Historic Overview of Its Description.
Karpathiou G, Hiroshima K, Peoc'h M
Adv Anat Pathol 2020 Nov;27(6):394-407. doi: 10.1097/PAP.0000000000000278. PMID: 32769378
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896
Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis.
Park JY, Kim KW, Kwon HJ, Park MS, Kwon GY, Jun SY, Yu ES
AJR Am J Roentgenol 2008 Sep;191(3):814-25. doi: 10.2214/AJR.07.3628. PMID: 18716115

Recent clinical studies

Etiology

Clinical Characteristics and Outcomes of Patients with Well-Differentiated Papillary Peritoneal Mesothelial Tumors.
Offin M, Aguirre N, Yang SR, Sauter JL, Karagkounis G, Mohamed M, Cercek A, Kundra R, Zhang Y, Wang HM, Morris MP, Ladanyi M, Nash GM, Zauderer MG
Ann Surg Oncol 2024 Nov;31(12):7973-7977. Epub 2024 Aug 21 doi: 10.1245/s10434-024-16004-2. PMID: 39167353Free PMC Article
Co-Localization of Gastrointestinal Stromal Tumors (GIST) and Peritoneal Mesothelioma: A Case Series.
Courelli AS, Sharma AK, Madlensky L, Choi YY, Li S, Sarno S, Kelly K, Mehtsun W, Horgan S, Harismendy O, Baumgartner JM, Sicklick JK
Ann Surg Oncol 2022 Nov;29(12):7542-7548. Epub 2022 Jul 18 doi: 10.1245/s10434-022-12211-x. PMID: 35849291Free PMC Article
Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Mesothelioma of the tunica vaginalis testis.
Butnor KJ, Pavlisko EN, Sporn TA, Roggli VL
Hum Pathol 2019 Oct;92:48-58. Epub 2019 Aug 1 doi: 10.1016/j.humpath.2019.07.009. PMID: 31376434
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896

Diagnosis

Molecular and Immunohistochemical Testing in Mesothelioma and Other Mesothelial Lesions.
Hung YP, Chirieac LR
Arch Pathol Lab Med 2024 May 1;148(5):e77-e89. doi: 10.5858/arpa.2023-0213-RA. PMID: 38190277
Peritoneal Mesothelioma-An Update.
Malpica A
Adv Anat Pathol 2023 Jul 1;30(4):262-274. Epub 2022 Dec 12 doi: 10.1097/PAP.0000000000000387. PMID: 36729766
Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Selected topics in peritoneal pathology.
Baker PM, Clement PB, Young RH
Int J Gynecol Pathol 2014 Jul;33(4):393-401. doi: 10.1097/PGP.0000000000000146. PMID: 24901399
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896

Therapy

Well differentiated papillary peritoneal mesothelioma treated by cytoreduction and hyperthermic intraperitoneal chemotherapy-the experience of the PSOGI registry.
Deraco M, Nizri E, Glehen O, Baratti D, Tuech JJ, Bereder JM, Kepenekian V, Kusamura S, Goere D
Eur J Surg Oncol 2019 Mar;45(3):371-375. Epub 2018 Oct 19 doi: 10.1016/j.ejso.2018.10.065. PMID: 30473172
Malignant peritoneal mesothelioma in patients with endometriosis.
Butnor KJ, Rueckert J, Pavlisko EN, Sporn TA, Roggli VL
J Clin Pathol 2018 Nov;71(11):971-974. Epub 2018 May 23 doi: 10.1136/jclinpath-2018-205099. PMID: 29794065
Therapeutic strategies for well-differentiated papillary mesothelioma of the peritoneum.
Lee YK, Jun HJ, Nahm JH, Lim TS, Park JS, Ahn JB, Rha SY, Chung HC, Oh HE, Song JS, Yang WI, Kim HS
Jpn J Clin Oncol 2013 Oct;43(10):996-1003. Epub 2013 Aug 20 doi: 10.1093/jjco/hyt117. PMID: 23964112
Peritoneal mesothelioma: the site of origin matters.
Kindler HL
Am Soc Clin Oncol Educ Book 2013:182-8. doi: 10.14694/EdBook_AM.2013.33.182. PMID: 23714495
Pathology of malignant mesothelioma.
Attanoos RL, Gibbs AR
Histopathology 1997 May;30(5):403-18. doi: 10.1046/j.1365-2559.1997.5460776.x. PMID: 9181361

Prognosis

Molecular and Immunohistochemical Testing in Mesothelioma and Other Mesothelial Lesions.
Hung YP, Chirieac LR
Arch Pathol Lab Med 2024 May 1;148(5):e77-e89. doi: 10.5858/arpa.2023-0213-RA. PMID: 38190277
Solid papillary mesothelial tumor.
Churg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F
Mod Pathol 2022 Jan;35(1):69-76. Epub 2021 Sep 3 doi: 10.1038/s41379-021-00899-3. PMID: 34480081
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896
Paratesticular mesothelial proliferations.
Churg A
Semin Diagn Pathol 2003 Nov;20(4):272-8. doi: 10.1053/j.semdp.2003.08.003. PMID: 14694980
Well-differentiated papillary mesothelioma.
Butnor KJ, Sporn TA, Hammar SP, Roggli VL
Am J Surg Pathol 2001 Oct;25(10):1304-9. doi: 10.1097/00000478-200110000-00012. PMID: 11688466

Clinical prediction guides

Molecular and Immunohistochemical Testing in Mesothelioma and Other Mesothelial Lesions.
Hung YP, Chirieac LR
Arch Pathol Lab Med 2024 May 1;148(5):e77-e89. doi: 10.5858/arpa.2023-0213-RA. PMID: 38190277
Co-Localization of Gastrointestinal Stromal Tumors (GIST) and Peritoneal Mesothelioma: A Case Series.
Courelli AS, Sharma AK, Madlensky L, Choi YY, Li S, Sarno S, Kelly K, Mehtsun W, Horgan S, Harismendy O, Baumgartner JM, Sicklick JK
Ann Surg Oncol 2022 Nov;29(12):7542-7548. Epub 2022 Jul 18 doi: 10.1245/s10434-022-12211-x. PMID: 35849291Free PMC Article
Well-Differentiated Papillary Mesothelioma of the Peritoneum: A Retrospective Study from the RENAPE Observational Registry.
Vogin G, Hettal L, Vignaud JM, Dartigues P, Goere D, Ferron G, Heyd B, Bereder JM, Tuech JJ, Glehen O, de Chaisemartin C, Lherm Y, Villeneuve L, Kepenekian V, Marchal F; RENAPE Network
Ann Surg Oncol 2019 Mar;26(3):852-860. Epub 2019 Jan 11 doi: 10.1245/s10434-018-07153-2. PMID: 30635798
Malignant peritoneal mesothelioma in patients with endometriosis.
Butnor KJ, Rueckert J, Pavlisko EN, Sporn TA, Roggli VL
J Clin Pathol 2018 Nov;71(11):971-974. Epub 2018 May 23 doi: 10.1136/jclinpath-2018-205099. PMID: 29794065
Well-differentiated papillary mesothelioma with invasive foci.
Churg A, Allen T, Borczuk AC, Cagle PT, Galateau-Sallé F, Hwang H, Murer B, Murty VV, Ordonez N, Tazelaar HD, Wick M
Am J Surg Pathol 2014 Jul;38(7):990-8. doi: 10.1097/PAS.0000000000000200. PMID: 24618613

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