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Ossifying fibroma of the jaw

MedGen UID:
892817
•Concept ID:
C4072940
•
Neoplastic Process
HPO: HP:0030427

Definition

A benign central bone tumor of the jaw composed of fibrous connective tissue within which bone is formed. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Ossifying fibroma of the jaw

Professional guidelines

PubMed

Pediatric Aggressive Benign Mandibular Tumors: Clinical Features and Management.
Koraitim M, Medra AM, Salloum AM, Shehata EA
J Craniofac Surg 2022 May 1;33(3):e265-e267. Epub 2021 Aug 13 doi: 10.1097/SCS.0000000000008085. PMID: 34387270
Diagnosis and management of benign fibro-osseous lesions of the jaws: a current review for the dental clinician.
Mainville GN, Turgeon DP, Kauzman A
Oral Dis 2017 May;23(4):440-450. Epub 2016 Aug 1 doi: 10.1111/odi.12531. PMID: 27387498
Maxillofacial fibro-osseous lesions: classification and differential diagnosis.
Slootweg PJ
Semin Diagn Pathol 1996 May;13(2):104-12. PMID: 8734416

Recent clinical studies

Etiology

Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases.
Han J, Hu L, Zhang C, Yang X, Tian Z, Wang Y, Zhu L, Yang C, Sun J, Zhang C, Li J, Xu L
Int J Oral Maxillofac Surg 2016 Mar;45(3):368-76. Epub 2015 Dec 28 doi: 10.1016/j.ijom.2015.12.004. PMID: 26740351
Benign Fibro-Osseous Lesions of the Jaws.
Abramovitch K, Rice DD
Dent Clin North Am 2016 Jan;60(1):167-93. Epub 2015 Oct 21 doi: 10.1016/j.cden.2015.08.010. PMID: 26614954
Maxillofacial fibro-osseous lesions.
MacDonald DS
Clin Radiol 2015 Jan;70(1):25-36. Epub 2014 Oct 17 doi: 10.1016/j.crad.2014.06.022. PMID: 25439185
Ossifying fibroma of the jaws: a clinical study of 14 cases and review of the literature.
Triantafillidou K, Venetis G, Karakinaris G, Iordanidis F
Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Aug;114(2):193-9. Epub 2012 Feb 25 doi: 10.1016/j.tripleo.2011.07.033. PMID: 22776732
Cemento-ossifying fibroma.
More C, Thakkar K, Asrani M
Indian J Dent Res 2011 Mar-Apr;22(2):352-5. doi: 10.4103/0970-9290.84296. PMID: 21891913

Diagnosis

Pediatric Gnathic Bony and Mesenchymal Tumors.
Liu Y, Housley Smith M, Patel PB, Bilodeau EA
Pediatr Dev Pathol 2023 Nov-Dec;26(6):621-641. Epub 2023 May 26 doi: 10.1177/10935266231170744. PMID: 37232383
Fibro-Osseous and Other Lesions of Bone in the Jaws.
Ahmad M, Gaalaas L
Radiol Clin North Am 2018 Jan;56(1):91-104. Epub 2017 Oct 19 doi: 10.1016/j.rcl.2017.08.007. PMID: 29157551
Bone-Related Lesions of the Jaws.
Baumhoer D
Surg Pathol Clin 2017 Sep;10(3):693-704. Epub 2017 Jun 2 doi: 10.1016/j.path.2017.04.007. PMID: 28797509
Maxillofacial fibro-osseous lesions.
MacDonald DS
Clin Radiol 2015 Jan;70(1):25-36. Epub 2014 Oct 17 doi: 10.1016/j.crad.2014.06.022. PMID: 25439185
Cemento-ossifying fibroma.
More C, Thakkar K, Asrani M
Indian J Dent Res 2011 Mar-Apr;22(2):352-5. doi: 10.4103/0970-9290.84296. PMID: 21891913

Therapy

Delayed Infection of Porous Polyethylene Implants After Oncologic Maxillectomy and Reconstruction: 2 Case Reports and Review of Literature.
Landry M, Hankins M, Berkovic J, Nathan CA
Ear Nose Throat J 2021 Dec;100(10_suppl):1023S-1026S. Epub 2020 Jun 15 doi: 10.1177/0145561320927525. PMID: 32538671
Hyperparathyroidism-jaw Tumor Syndrome: An Overlooked Cause of Severe Hypercalcemia.
Mathews JW, Winchester R, Alsaygh N, Bartlett AM, Luttrell L
Am J Med Sci 2016 Sep;352(3):302-5. Epub 2016 Jul 1 doi: 10.1016/j.amjms.2016.06.020. PMID: 27650236
Peritrabecular clefting in fibrous dysplasia of the jaws: an important histopathologic feature for differentiating fibrous dysplasia from central ossifying fibroma.
Prado Ribeiro AC, Carlos R, Speight PM, Hunter KD, Santos-Silva AR, de Almeida OP, Vargas PA
Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Oct;114(4):503-8. doi: 10.1016/j.oooo.2012.06.014. PMID: 22986246
Retropharyngeal dissection during nasotracheal intubation: a rare complication and its management.
Krebs MJ, Sakai T
J Clin Anesth 2008 May;20(3):218-21. doi: 10.1016/j.jclinane.2007.09.021. PMID: 18502368
Peripheral ossifying fibroma in a child: report of case.
Hanemann JA, Pereira AA, Ribeiro Júnior NV, Oliveira DT
J Clin Pediatr Dent 2003 Spring;27(3):283-5. PMID: 12739692

Prognosis

Retrospective Study of 383 Cases of Fibro-Osseous Lesions of the Jaws.
Kato CNAO, Nunes LFM, Chalub LLFH, Etges A, Silva TA, Mesquita RA
J Oral Maxillofac Surg 2018 Nov;76(11):2348-2359. Epub 2018 May 10 doi: 10.1016/j.joms.2018.04.037. PMID: 29859157
A Case Series of Fibro-Osseous Lesions of the Jaws.
Akashi M, Matsuo K, Shigeoka M, Kakei Y, Hasegawa T, Tachibana A, Furudoi S, Komori T
Kobe J Med Sci 2017 Dec 18;63(3):E73-E79. PMID: 29434178Free PMC Article
Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases.
Han J, Hu L, Zhang C, Yang X, Tian Z, Wang Y, Zhu L, Yang C, Sun J, Zhang C, Li J, Xu L
Int J Oral Maxillofac Surg 2016 Mar;45(3):368-76. Epub 2015 Dec 28 doi: 10.1016/j.ijom.2015.12.004. PMID: 26740351
Ossifying fibroma of the jaws: a clinical study of 14 cases and review of the literature.
Triantafillidou K, Venetis G, Karakinaris G, Iordanidis F
Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Aug;114(2):193-9. Epub 2012 Feb 25 doi: 10.1016/j.tripleo.2011.07.033. PMID: 22776732
Cemento-ossifying fibroma.
More C, Thakkar K, Asrani M
Indian J Dent Res 2011 Mar-Apr;22(2):352-5. doi: 10.4103/0970-9290.84296. PMID: 21891913

Clinical prediction guides

Retrospective Study of 383 Cases of Fibro-Osseous Lesions of the Jaws.
Kato CNAO, Nunes LFM, Chalub LLFH, Etges A, Silva TA, Mesquita RA
J Oral Maxillofac Surg 2018 Nov;76(11):2348-2359. Epub 2018 May 10 doi: 10.1016/j.joms.2018.04.037. PMID: 29859157
Peripheral Cemento-Ossifying Fibroma.
Humagain M , Dawadi A , Srii R , Poudel P
Kathmandu Univ Med J (KUMJ) 2017 Jul-Sept.;15(59):261-264. PMID: 30353905
Which Patients With Ossifying Fibroma of the Jaws Would Be Suitable for Radical Ablative Surgery?
Lv M, Shen Y, Li J, Gvetadze SR, Sun J
J Craniofac Surg 2016 Jun;27(4):927-31. doi: 10.1097/SCS.0000000000002653. PMID: 27192645
Microsurgical reconstruction of the maxilla: Algorithm and concepts.
Costa H, Zenha H, Sequeira H, Coelho G, Gomes N, Pinto C, Martins J, Santos D, Andresen C
J Plast Reconstr Aesthet Surg 2015 May;68(5):e89-e104. Epub 2015 Jan 14 doi: 10.1016/j.bjps.2014.12.002. PMID: 25778873
Mineralized components and their interpretation in the histogenesis of peripheral ossifying fibroma.
Shetty DC, Urs AB, Ahuja P, Sahu A, Manchanda A, Sirohi Y
Indian J Dent Res 2011 Jan-Feb;22(1):56-61. doi: 10.4103/0970-9290.79976. PMID: 21525678

Recent systematic reviews

Juvenile psammomatoid ossifying fibroma of the maxilla and mandible: A systematic review of published case reports.
R C, R S, Mohideen K, Balasubramaniam M, Ghosh S, Dhungel S
Clin Exp Dent Res 2023 Feb;9(1):186-197. Epub 2022 Nov 3 doi: 10.1002/cre2.687. PMID: 36325758Free PMC Article
A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws.
Alsufyani NA, Aldosary RM, Alrasheed RS, Alsaif RF
Acta Odontol Scand 2021 Mar;79(2):124-131. Epub 2020 Jul 30 doi: 10.1080/00016357.2020.1797160. PMID: 32730731
Ossifying fibroma: a systematic review.
MacDonald-Jankowski DS
Dentomaxillofac Radiol 2009 Dec;38(8):495-513. doi: 10.1259/dmfr/70933621. PMID: 20026707

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