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Abnormal cerebrospinal fluid morphology

MedGen UID:
488781
•Concept ID:
C0151583
•
Finding
Synonym: Abnormality of the cerebrospinal fluid
 
HPO: HP:0002921

Definition

An abnormality of the cerebrospinal fluid (CSF). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal cerebrospinal fluid morphology

Professional guidelines

PubMed

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.
Jack CR Jr, Andrews JS, Beach TG, Buracchio T, Dunn B, Graf A, Hansson O, Ho C, Jagust W, McDade E, Molinuevo JL, Okonkwo OC, Pani L, Rafii MS, Scheltens P, Siemers E, Snyder HM, Sperling R, Teunissen CE, Carrillo MC
Alzheimers Dement 2024 Aug;20(8):5143-5169. Epub 2024 Jun 27 doi: 10.1002/alz.13859. PMID: 38934362Free PMC Article
Chronic inflammatory demyelinating polyradiculoneuropathy-Diagnostic pitfalls and treatment approach.
Stino AM, Naddaf E, Dyck PJ, Dyck PJB
Muscle Nerve 2021 Feb;63(2):157-169. Epub 2020 Sep 11 doi: 10.1002/mus.27046. PMID: 32914902
Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype.
Vermunt L, Sikkes SAM, van den Hout A, Handels R, Bos I, van der Flier WM, Kern S, Ousset PJ, Maruff P, Skoog I, Verhey FRJ, Freund-Levi Y, Tsolaki M, Wallin ÅK, Olde Rikkert M, Soininen H, Spiru L, Zetterberg H, Blennow K, Scheltens P, Muniz-Terrera G, Visser PJ; Alzheimer Disease Neuroimaging Initiative; AIBL Research Group; ICTUS/DSA study groups
Alzheimers Dement 2019 Jul;15(7):888-898. Epub 2019 Jun 1 doi: 10.1016/j.jalz.2019.04.001. PMID: 31164314Free PMC Article

Recent clinical studies

Etiology

Biomechanical instability of the brain-CSF interface in hydrocephalus.
Duy PQ, Mehta NH, Kahle KT
Brain 2024 Oct 3;147(10):3274-3285. doi: 10.1093/brain/awae155. PMID: 38798141Free PMC Article
Cerebrospinal fluid leaks following septoplasty.
Venkatesan NN, Mattox DE, Del Gaudio JM
Ear Nose Throat J 2014 Dec;93(12):E43-6. doi: 10.1177/014556131409301204. PMID: 25531856
Hemihydranencephaly: living with half brain dysfunction.
Pavone P, Nigro F, Falsaperla R, Greco F, Ruggieri M, Rizzo R, Praticò AD, Pavone L
Ital J Pediatr 2013 Jan 16;39:3. doi: 10.1186/1824-7288-39-3. PMID: 23324549Free PMC Article
Congenital hydrocephalus associated with myeloschisis.
Jeelani Y, McComb JG
Childs Nerv Syst 2011 Oct;27(10):1585-8. Epub 2011 Sep 17 doi: 10.1007/s00381-011-1560-4. PMID: 21928024
Reduction cranioplasty.
Winston KR, Ogilvy CS, McGrail K
Pediatr Neurosurg 1995;22(5):228-34. doi: 10.1159/000120906. PMID: 7547453

Diagnosis

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development.
Xu H, Fame RM, Sadegh C, Sutin J, Naranjo C, Della Syau, Cui J, Shipley FB, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Warf BC, Lin PY, Lehtinen MK
Nat Commun 2021 Jan 19;12(1):447. doi: 10.1038/s41467-020-20666-3. PMID: 33469018Free PMC Article
Chronic inflammatory demyelinating polyradiculoneuropathy-Diagnostic pitfalls and treatment approach.
Stino AM, Naddaf E, Dyck PJ, Dyck PJB
Muscle Nerve 2021 Feb;63(2):157-169. Epub 2020 Sep 11 doi: 10.1002/mus.27046. PMID: 32914902
Hemihydranencephaly: living with half brain dysfunction.
Pavone P, Nigro F, Falsaperla R, Greco F, Ruggieri M, Rizzo R, Praticò AD, Pavone L
Ital J Pediatr 2013 Jan 16;39:3. doi: 10.1186/1824-7288-39-3. PMID: 23324549Free PMC Article
Neurocutaneous melanosis.
Burstein F, Seier H, Hudgins PA, Zapiach L
J Craniofac Surg 2005 Sep;16(5):874-6. doi: 10.1097/01.scs.0000181050.06696.4d. PMID: 16192875
Neurosyphilis.
Kolar OJ, Burkhart JE
Br J Vener Dis 1977 Aug;53(4):221-5. doi: 10.1136/sti.53.4.221. PMID: 336144Free PMC Article

Therapy

Monobloc Distraction and Facial Bipartition Distraction with External Devices.
Dunaway DJ, Budden C, Ong J, James G, Jeelani NUO
Clin Plast Surg 2021 Jul;48(3):507-519. doi: 10.1016/j.cps.2021.03.004. PMID: 34051902
Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development.
Xu H, Fame RM, Sadegh C, Sutin J, Naranjo C, Della Syau, Cui J, Shipley FB, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Warf BC, Lin PY, Lehtinen MK
Nat Commun 2021 Jan 19;12(1):447. doi: 10.1038/s41467-020-20666-3. PMID: 33469018Free PMC Article
Chronic inflammatory demyelinating polyradiculoneuropathy-Diagnostic pitfalls and treatment approach.
Stino AM, Naddaf E, Dyck PJ, Dyck PJB
Muscle Nerve 2021 Feb;63(2):157-169. Epub 2020 Sep 11 doi: 10.1002/mus.27046. PMID: 32914902
Subacute sclerosing panencephalitis.
Garg RK, Mahadevan A, Malhotra HS, Rizvi I, Kumar N, Uniyal R
Rev Med Virol 2019 Sep;29(5):e2058. Epub 2019 Jun 24 doi: 10.1002/rmv.2058. PMID: 31237061
Spontaneous CSF Leaks.
Wang EW, Vandergrift WA 3rd, Schlosser RJ
Otolaryngol Clin North Am 2011 Aug;44(4):845-56, vii. doi: 10.1016/j.otc.2011.06.018. PMID: 21819875

Prognosis

Evaluation of Long-Term Follow-Up in Ecchordosis Physaliphora versus Chordoma.
Stuebe CM, Rindler RS, Laack N, Carr CM, Choby G, Inwards CY, Van Gompel JJ
World Neurosurg 2023 Jun;174:157-168. Epub 2023 Mar 9 doi: 10.1016/j.wneu.2023.03.016. PMID: 36898627
Prognostic value of acute cerebrospinal fluid abnormalities in antibody-positive autoimmune encephalitis.
Broadley J, Wesselingh R, Seneviratne U, Kyndt C, Beech P, Buzzard K, Nesbitt C, D'souza W, Brodtmann A, Macdonell R, Kalincik T, Butzkueven H, O'Brien TJ, Monif M; Australian Autoimmune Encephalitis Consortium
J Neuroimmunol 2021 Apr 15;353:577508. Epub 2021 Jan 30 doi: 10.1016/j.jneuroim.2021.577508. PMID: 33588218
Neurocutaneous melanosis.
Burstein F, Seier H, Hudgins PA, Zapiach L
J Craniofac Surg 2005 Sep;16(5):874-6. doi: 10.1097/01.scs.0000181050.06696.4d. PMID: 16192875
Pediatric cerebellar hemorrhages.
Chadduck WM, Duong DH, Kast JM, Donahue DJ
Childs Nerv Syst 1995 Oct;11(10):579-83. doi: 10.1007/BF00300996. PMID: 8556724
Syringomyelia and arachnoiditis.
Caplan LR, Norohna AB, Amico LL
J Neurol Neurosurg Psychiatry 1990 Feb;53(2):106-13. doi: 10.1136/jnnp.53.2.106. PMID: 2313296Free PMC Article

Clinical prediction guides

Classification and Current Management of Inner Ear Malformations.
Sennaroğlu L, Bajin MD
Balkan Med J 2017 Sep 29;34(5):397-411. Epub 2017 Aug 25 doi: 10.4274/balkanmedj.2017.0367. PMID: 28840850Free PMC Article
A Case of Cutaneous Meningioma in the Rudimentary Meningocele.
Ochiai J, Yamaguchi S, Takeda M, Adhikari RB, Kolakshyapati M, Karlowee V, Sugiyama K, Kurisu K
Hiroshima J Med Sci 2016 Mar;65(1):9-12. PMID: 27348900
Inflammation in epilepsy: clinical observations.
Aronica E, Crino PB
Epilepsia 2011 May;52 Suppl 3:26-32. doi: 10.1111/j.1528-1167.2011.03033.x. PMID: 21542843
The neuropathology of Rett syndrome--overview 1994.
Armstrong DD
Neuropediatrics 1995 Apr;26(2):100-4. doi: 10.1055/s-2007-979736. PMID: 7566445
Reduction of cortical volume in schizophrenia on magnetic resonance imaging.
Harvey I, Ron MA, Du Boulay G, Wicks D, Lewis SW, Murray RM
Psychol Med 1993 Aug;23(3):591-604. doi: 10.1017/s003329170002537x. PMID: 8234567

Recent systematic reviews

The Lost and Variable Cause: A Systematic Review of Shunt-Related Craniosynostosis Occurrence.
LaValley MN, Asadourian PA, Valenti AB, Hoffman CE, Imahiyerobo TA
J Craniofac Surg 2024 Jul-Aug 01;35(5):1466-1470. Epub 2024 Jun 11 doi: 10.1097/SCS.0000000000010404. PMID: 38861334
Diagnostic accuracy of intrathecal fluorescein versus other radiological modalities in evaluating non-congenital skull base defects: a systematic review and meta-analysis.
AlSharhan SS, Aljubran HJ, Alrusayyis DF, AlGhuneem AA, AlMarzouq WF, Al Bar MH, AlSaied AS, Ashoor MM, ALEnazi AS, Alghamdi AA
Eur Arch Otorhinolaryngol 2024 Sep;281(9):4435-4454. Epub 2024 Apr 6 doi: 10.1007/s00405-024-08603-2. PMID: 38581572Free PMC Article
Diagnostic value of α-synuclein seeding amplification assays in α-synucleinopathies: A systematic review and meta-analysis.
Yoo D, Bang JI, Ahn C, Nyaga VN, Kim YE, Kang MJ, Ahn TB
Parkinsonism Relat Disord 2022 Nov;104:99-109. Epub 2022 Oct 19 doi: 10.1016/j.parkreldis.2022.10.007. PMID: 36289019
Primary Angiitis of the CNS: A Systematic Review and Meta-analysis.
Beuker C, Strunk D, Rawal R, Schmidt-Pogoda A, Werring N, Milles L, Ruck T, Wiendl H, Meuth S, Minnerup H, Minnerup J
Neurol Neuroimmunol Neuroinflamm 2021 Nov;8(6) Epub 2021 Oct 18 doi: 10.1212/NXI.0000000000001093. PMID: 34663675Free PMC Article
Unruptured brain arteriovenous malformations and hydrocephalus: Case series and review of the literature.
De Maria L, Brinjikji W, Lanzino G
J Clin Neurosci 2019 Jun;64:116-121. Epub 2019 Apr 1 doi: 10.1016/j.jocn.2019.03.042. PMID: 30948310

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