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Series GSE52576 Query DataSets for GSE52576
Status Public on Dec 28, 2013
Title Genome-wide parent-of-origin DNA methylation analysis [Methylation450 BeadChip]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genomic imprinting is a form of epigenetic regulation that results in expression of either the maternally or paternally inherited allele of a subset of genes. Imprinted loci contain differentially methylated regions (DMRs) where cytosine methylation marks one of the parental alleles, providing cis-acting regulatory elements that influence the allelic expression of surrounding genes, however to date the total number of imprinted loci within the human genome is unknown. To characterize known imprinted DMRS and identify novel imprinted loci we have performed whole-genome bisulphite sequencing and high-resolution DNA methylation array analysis of healthy tissues.
Overall design Sequencing of bisulfite converted DNA and array based analysis of normal tissues, human embryonic stem cells, androgenetic hydatidiform moles and leukocytes from reciprocal genome-wide uniparental disomies.
Contributor(s) Monk D, Nakabayashi K, Esteller M
Citation(s) 24402520, 26544189
Submission date Nov 20, 2013
Last update date Mar 22, 2019
Contact name Manel Esteller
Organization name IDIBELL
Department PEBC
Lab Cancer Epigenetics
Street address Hospital Duran i Reynals Av. Gran Via s/n km, 2.7
City L'Hospitalet de Llobregat
State/province Barcelona
ZIP/Postal code 08908
Country Spain
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (28)
GSM1270013 Brain 2
GSM1270014 Brain 1
GSM1270015 Muscle
This SubSeries is part of SuperSeries:
GSE52578 Genome-wide parent-of-origin DNA methylation analysis
BioProject PRJNA229408

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52576_RAW.tar 183.1 Mb (http)(custom) TAR
GSE52576_complete_data.txt.gz 238.9 Mb (ftp)(http) TXT
Processed data included within Sample table

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