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Connective and Soft Tissue Disorder

MedGen UID:
272508
•Concept ID:
C1333150
•
Disease or Syndrome
Synonyms: Connective and Soft Tissue Disease; Connective and Soft Tissue Diseases

Definition

A non-neoplastic or neoplastic disorder that affects the connective and soft tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConnective and Soft Tissue Disorder

Professional guidelines

PubMed

Scleroderma of the Hand: Evaluation and Treatment.
Beldner S, Rabinovich RV, Polatsch DB
J Am Acad Orthop Surg 2020 Aug 15;28(16):e686-e695. doi: 10.5435/JAAOS-D-19-00547. PMID: 32769717
Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement.
Zügel M, Maganaris CN, Wilke J, Jurkat-Rott K, Klingler W, Wearing SC, Findley T, Barbe MF, Steinacker JM, Vleeming A, Bloch W, Schleip R, Hodges PW
Br J Sports Med 2018 Dec;52(23):1497. Epub 2018 Aug 2 doi: 10.1136/bjsports-2018-099308. PMID: 30072398Free PMC Article
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632

Recent clinical studies

Etiology

The Ehlers-Danlos syndromes.
Malfait F, Castori M, Francomano CA, Giunta C, Kosho T, Byers PH
Nat Rev Dis Primers 2020 Jul 30;6(1):64. doi: 10.1038/s41572-020-0194-9. PMID: 32732924
Peri-implantitis.
Schwarz F, Derks J, Monje A, Wang HL
J Periodontol 2018 Jun;89 Suppl 1:S267-S290. doi: 10.1002/JPER.16-0350. PMID: 29926957
Peri-implant mucositis.
Heitz-Mayfield LJA, Salvi GE
J Clin Periodontol 2018 Jun;45 Suppl 20:S237-S245. doi: 10.1111/jcpe.12953. PMID: 29926488
Peri-implantitis.
Schwarz F, Derks J, Monje A, Wang HL
J Clin Periodontol 2018 Jun;45 Suppl 20:S246-S266. doi: 10.1111/jcpe.12954. PMID: 29926484
Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis.
Thoma DS, Naenni N, Figuero E, Hämmerle CHF, Schwarz F, Jung RE, Sanz-Sánchez I
Clin Oral Implants Res 2018 Mar;29 Suppl 15:32-49. doi: 10.1111/clr.13114. PMID: 29498129

Diagnosis

Musculoskeletal mimics of cervical radiculopathy.
Chiou-Tan FY
Muscle Nerve 2022 Jul;66(1):6-14. Epub 2022 Apr 24 doi: 10.1002/mus.27553. PMID: 35466429
The Ehlers-Danlos syndromes.
Malfait F, Castori M, Francomano CA, Giunta C, Kosho T, Byers PH
Nat Rev Dis Primers 2020 Jul 30;6(1):64. doi: 10.1038/s41572-020-0194-9. PMID: 32732924
Peri-implantitis.
Schwarz F, Derks J, Monje A, Wang HL
J Periodontol 2018 Jun;89 Suppl 1:S267-S290. doi: 10.1002/JPER.16-0350. PMID: 29926957
Peri-implantitis.
Schwarz F, Derks J, Monje A, Wang HL
J Clin Periodontol 2018 Jun;45 Suppl 20:S246-S266. doi: 10.1111/jcpe.12954. PMID: 29926484
Hypermobile Ehlers-Danlos syndrome (a.k.a. Ehlers-Danlos syndrome Type III and Ehlers-Danlos syndrome hypermobility type): Clinical description and natural history.
Tinkle B, Castori M, Berglund B, Cohen H, Grahame R, Kazkaz H, Levy H
Am J Med Genet C Semin Med Genet 2017 Mar;175(1):48-69. Epub 2017 Feb 1 doi: 10.1002/ajmg.c.31538. PMID: 28145611

Therapy

Do soft tissue augmentation techniques provide stable and favorable peri-implant conditions in the medium and long term? A systematic review.
Stefanini M, Barootchi S, Sangiorgi M, Pispero A, Grusovin MG, Mancini L, Zucchelli G, Tavelli L
Clin Oral Implants Res 2023 Sep;34 Suppl 26:28-42. doi: 10.1111/clr.14150. PMID: 37750532
Implant connection and abutment selection as a predisposing and/or precipitating factor for peri-implant diseases: A review.
Laleman I, Lambert F
Clin Implant Dent Relat Res 2023 Aug;25(4):723-733. Epub 2023 Feb 24 doi: 10.1111/cid.13185. PMID: 36825512
Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis.
Thoma DS, Naenni N, Figuero E, Hämmerle CHF, Schwarz F, Jung RE, Sanz-Sánchez I
Clin Oral Implants Res 2018 Mar;29 Suppl 15:32-49. doi: 10.1111/clr.13114. PMID: 29498129
Comparison of peri-implant and periodontal marginal soft tissues in health and disease.
Ivanovski S, Lee R
Periodontol 2000 2018 Feb;76(1):116-130. Epub 2017 Nov 30 doi: 10.1111/prd.12150. PMID: 29193334
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632

Prognosis

Human monkeypox disease.
Srivastava G, Srivastava G
Clin Dermatol 2022 Sep-Oct;40(5):604-612. Epub 2022 Aug 10 doi: 10.1016/j.clindermatol.2022.08.009. PMID: 35963500Free PMC Article
Interproximal attachment gain: The challenge of periodontal regeneration.
Rasperini G, Tavelli L, Barootchi S, McGuire MK, Zucchelli G, Pagni G, Stefanini M, Wang HL, Giannobile WV
J Periodontol 2021 Jul;92(7):931-946. Epub 2020 Nov 23 doi: 10.1002/JPER.20-0587. PMID: 33152103
MRI of the Neonatal Brain: A Review of Methodological Challenges and Neuroscientific Advances.
Dubois J, Alison M, Counsell SJ, Hertz-Pannier L, Hüppi PS, Benders MJNL
J Magn Reson Imaging 2021 May;53(5):1318-1343. Epub 2020 May 18 doi: 10.1002/jmri.27192. PMID: 32420684Free PMC Article
Carpal Tunnel Syndrome: A Potential Early, Red-Flag Sign of Amyloidosis.
Donnelly JP, Hanna M, Sperry BW, Seitz WH Jr
J Hand Surg Am 2019 Oct;44(10):868-876. Epub 2019 Aug 7 doi: 10.1016/j.jhsa.2019.06.016. PMID: 31400950
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632

Clinical prediction guides

Do soft tissue augmentation techniques provide stable and favorable peri-implant conditions in the medium and long term? A systematic review.
Stefanini M, Barootchi S, Sangiorgi M, Pispero A, Grusovin MG, Mancini L, Zucchelli G, Tavelli L
Clin Oral Implants Res 2023 Sep;34 Suppl 26:28-42. doi: 10.1111/clr.14150. PMID: 37750532
Pediatric joint hypermobility: a diagnostic framework and narrative review.
Tofts LJ, Simmonds J, Schwartz SB, Richheimer RM, O'Connor C, Elias E, Engelbert R, Cleary K, Tinkle BT, Kline AD, Hakim AJ, van Rossum MAJ, Pacey V
Orphanet J Rare Dis 2023 May 4;18(1):104. doi: 10.1186/s13023-023-02717-2. PMID: 37143135Free PMC Article
Evidence-based knowledge on the aesthetics and maintenance of peri-implant soft tissues: Osteology Foundation Consensus Report Part 1-Effects of soft tissue augmentation procedures on the maintenance of peri-implant soft tissue health.
Giannobile WV, Jung RE, Schwarz F; Groups of the 2nd Osteology Foundation Consensus Meeting
Clin Oral Implants Res 2018 Mar;29 Suppl 15:7-10. doi: 10.1111/clr.13110. PMID: 29498127
Nonsurgical periodontal treatment.
Aimetti M
Int J Esthet Dent 2014 Summer;9(2):251-67. PMID: 24765632
Clinical and genetic aspects of Ehlers-Danlos syndrome, classic type.
Malfait F, Wenstrup RJ, De Paepe A
Genet Med 2010 Oct;12(10):597-605. doi: 10.1097/GIM.0b013e3181eed412. PMID: 20847697

Recent systematic reviews

Clinical Characteristics of Malignant Phosphaturic Mesenchymal Tumor Causing Tumor-Induced Osteomalacia.
Abate V, Vergatti A, De Filippo G, Damiano V, Menale C, D'Elia L, Rendina D
J Clin Endocrinol Metab 2024 Feb 20;109(3):e1006-e1011. doi: 10.1210/clinem/dgad690. PMID: 38006315
Do soft tissue augmentation techniques provide stable and favorable peri-implant conditions in the medium and long term? A systematic review.
Stefanini M, Barootchi S, Sangiorgi M, Pispero A, Grusovin MG, Mancini L, Zucchelli G, Tavelli L
Clin Oral Implants Res 2023 Sep;34 Suppl 26:28-42. doi: 10.1111/clr.14150. PMID: 37750532
The Efficacy of Physical Therapy and Rehabilitation Approaches in Chronic Migraine: A Systematic Review and Meta-Analysis.
Onan D, Ekizoğlu E, Arıkan H, Taşdelen B, Özge A, Martelletti P
J Integr Neurosci 2023 Aug 16;22(5):126. doi: 10.31083/j.jin2205126. PMID: 37735140
Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis.
Thoma DS, Naenni N, Figuero E, Hämmerle CHF, Schwarz F, Jung RE, Sanz-Sánchez I
Clin Oral Implants Res 2018 Mar;29 Suppl 15:32-49. doi: 10.1111/clr.13114. PMID: 29498129
Evidence-based knowledge on the aesthetics and maintenance of peri-implant soft tissues: Osteology Foundation Consensus Report Part 1-Effects of soft tissue augmentation procedures on the maintenance of peri-implant soft tissue health.
Giannobile WV, Jung RE, Schwarz F; Groups of the 2nd Osteology Foundation Consensus Meeting
Clin Oral Implants Res 2018 Mar;29 Suppl 15:7-10. doi: 10.1111/clr.13110. PMID: 29498127

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