U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ludwig angina

MedGen UID:
44205
•Concept ID:
C0024081
•
Disease or Syndrome
Synonym: Ludwig's angina
SNOMED CT: Ludwig angina (196542004); Ludwig's angina (196542004)
 
Monarch Initiative: MONDO:0006576

Definition

Severe cellulitis of the submaxillary space with secondary involvement of the sublingual and submental space. It usually results from infection in the lower molar area or from a penetrating injury to the mouth floor. (From Dorland, 27th ed) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLudwig angina

Professional guidelines

PubMed

Management of pediatric head and neck infections in the emergency department.
Abudinen-Vasquez S, Marin MN
Pediatr Emerg Med Pract 2020 Nov;17(11):1-24. Epub 2020 Nov 2 PMID: 33105074
Characteristics and management of patients requiring hospitalization for treatment of odontogenic infections.
Gonçalves L, Lauriti L, Yamamoto MK, Luz JG
J Craniofac Surg 2013;24(5):e458-62. doi: 10.1097/SCS.0b013e3182902e95. PMID: 24036813
Ludwig angina: a review of current airway management.
Marple BF
Arch Otolaryngol Head Neck Surg 1999 May;125(5):596-9. doi: 10.1001/archotol.125.5.596. PMID: 10326823

Recent clinical studies

Etiology

Major complications after tongue-tie release: A case report and systematic review.
Solis-Pazmino P, Kim GS, Lincango-Naranjo E, Prokop L, Ponce OJ, Truong MT
Int J Pediatr Otorhinolaryngol 2020 Nov;138:110356. Epub 2020 Sep 1 doi: 10.1016/j.ijporl.2020.110356. PMID: 32927351
Should we consider IgG hypogammaglobulinemia a risk factor for severe complications of Ludwig angina?: A case report and review of the literature.
Baez-Pravia OV, Díaz-Cámara M, De La O, Pey C, Ontañón Martín M, Jimenez Hiscock L, Morató Bellido B, Córdoba Sánchez ÁL
Medicine (Baltimore) 2017 Nov;96(47):e8708. doi: 10.1097/MD.0000000000008708. PMID: 29381958Free PMC Article
Longitudinal discharge trends and outcomes after hospitalization for mouth cellulitis and Ludwig angina.
Allareddy V, Rampa S, Nalliah RP, Allareddy V
Oral Surg Oral Med Oral Pathol Oral Radiol 2014 Nov;118(5):524-31. Epub 2014 Jun 14 doi: 10.1016/j.oooo.2014.06.003. PMID: 25216950
Characteristics and management of patients requiring hospitalization for treatment of odontogenic infections.
Gonçalves L, Lauriti L, Yamamoto MK, Luz JG
J Craniofac Surg 2013;24(5):e458-62. doi: 10.1097/SCS.0b013e3182902e95. PMID: 24036813
Is surgical airway necessary for airway management in deep neck infections and Ludwig angina?
Wolfe MM, Davis JW, Parks SN
J Crit Care 2011 Feb;26(1):11-4. doi: 10.1016/j.jcrc.2010.02.016. PMID: 20537506

Diagnosis

Ludwig angina and sudden death.
Tu A, Gilbert JD, Byard RW
Forensic Sci Med Pathol 2021 Sep;17(3):506-509. Epub 2021 Jan 22 doi: 10.1007/s12024-020-00350-0. PMID: 33481171
Infections of the Neck.
Li RM, Kiemeney M
Emerg Med Clin North Am 2019 Feb;37(1):95-107. doi: 10.1016/j.emc.2018.09.003. PMID: 30454783
Ludwig angina.
Kobayashi M, Watanabe K
CMAJ 2017 Feb 13;189(6):E246. Epub 2016 Dec 12 doi: 10.1503/cmaj.160279. PMID: 27956390Free PMC Article
Infections and edema.
Linkov G, Soliman AM
Anesthesiol Clin 2015 Jun;33(2):329-46. doi: 10.1016/j.anclin.2015.02.005. PMID: 25999006
Ludwig angina.
Cahill D
Am J Nurs 2002 Oct;102(10):43-4. doi: 10.1097/00000446-200210000-00020. PMID: 12394305

Therapy

Ludwig's angina and steroid use: A narrative review.
Tami A, Othman S, Sudhakar A, McKinnon BJ
Am J Otolaryngol 2020 May-Jun;41(3):102411. Epub 2020 Feb 1 doi: 10.1016/j.amjoto.2020.102411. PMID: 32035654
Pseudo-Ludwig angina.
Tiu A, Lapumnuaypol K
Cleve Clin J Med 2019 Sep;86(9):577-578. doi: 10.3949/ccjm.86a.19014. PMID: 31498770
Ludwig angina.
Kobayashi M, Watanabe K
CMAJ 2017 Feb 13;189(6):E246. Epub 2016 Dec 12 doi: 10.1503/cmaj.160279. PMID: 27956390Free PMC Article
Extracranial head and neck infections.
Jaworsky D, Reynolds S, Chow AW
Crit Care Clin 2013 Jul;29(3):443-63. doi: 10.1016/j.ccc.2013.03.003. PMID: 23830648
Ludwig angina.
Cahill D
Am J Nurs 2002 Oct;102(10):43-4. doi: 10.1097/00000446-200210000-00020. PMID: 12394305

Prognosis

Ludwig's angina: A diagnostic and surgical priority.
Vallée M, Gaborit B, Meyer J, Malard O, Boutoille D, Raffi F, Espitalier F, Asseray N
Int J Infect Dis 2020 Apr;93:160-162. Epub 2020 Jan 23 doi: 10.1016/j.ijid.2020.01.028. PMID: 31981767
Ludwig Angina after First Aid Treatment: Possible Etiologies and Prevention-Case Report.
Shemesh A, Yitzhak A, Ben Itzhak J, Azizi H, Solomonov M
J Endod 2019 Jan;45(1):79-82. Epub 2018 Nov 13 doi: 10.1016/j.joen.2018.10.001. PMID: 30446404
Mucormycosis Causing Ludwig Angina: A Unique Presentation.
McSpadden RP, Martin JR, Mehrotra S, Thorpe E
J Oral Maxillofac Surg 2017 Apr;75(4):759-762. Epub 2016 Oct 29 doi: 10.1016/j.joms.2016.10.025. PMID: 27875707
Ludwig angina progressing to fatal necrotizing fasciitis.
Blanchard A, Garza Garcia L, Palacios E, Bordlee B Jr, Neitzschman H
Ear Nose Throat J 2013 Mar;92(3):102-4. doi: 10.1177/014556131309200306. PMID: 23532644
Chronic osteomyelitis following an uncomplicated dental extraction.
Humber CC, Albilia JB, Rittenberg B
J Can Dent Assoc 2011;77:b98. PMID: 21810374

Clinical prediction guides

Post-mortem CT findings in a case of necrotizing cellulitis of the floor of the mouth (Ludwig angina).
Lee WI, Lee J, Bassed R, O'Donnell C
Forensic Sci Med Pathol 2014 Mar;10(1):109-13. Epub 2013 Oct 23 doi: 10.1007/s12024-013-9499-2. PMID: 24150965
An upper airway obstruction emergency: Ludwig angina.
Chou YK, Lee CY, Chao HH
Pediatr Emerg Care 2007 Dec;23(12):892-6. doi: 10.1097/pec.0b013e31815c9d4a. PMID: 18091599

Recent systematic reviews

Major complications after tongue-tie release: A case report and systematic review.
Solis-Pazmino P, Kim GS, Lincango-Naranjo E, Prokop L, Ponce OJ, Truong MT
Int J Pediatr Otorhinolaryngol 2020 Nov;138:110356. Epub 2020 Sep 1 doi: 10.1016/j.ijporl.2020.110356. PMID: 32927351
Ludwig's angina and steroid use: A narrative review.
Tami A, Othman S, Sudhakar A, McKinnon BJ
Am J Otolaryngol 2020 May-Jun;41(3):102411. Epub 2020 Feb 1 doi: 10.1016/j.amjoto.2020.102411. PMID: 32035654

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...