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Benign Fibrohistiocytic Neoplasm

MedGen UID:: 231935
•Concept ID:: C1332500
•: Neoplastic Process

Synonyms:	Benign fibrohistiocytic neoplasm; Benign fibrohistiocytic tumor; Benign Fibrohistiocytic Tumor
SNOMED CT:	Benign fibrohistiocytic neoplasm (721581002); Benign fibrohistiocytic tumor (721581002); Benign fibrohistiocytic neoplasm (1187238004)

Definition

A mesenchymal neoplasm composed of fibrohistiocytic cells, spindle fibroblastic cells, and histiocytes, in a storiform pattern. There is no evidence of atypical or malignant cytological and architectural features, invasive features, or metastases. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign Fibrohistiocytic Neoplasm

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Benign neoplasm
        Benign connective and soft tissue neoplasm
        Benign Fibrohistiocytic Neoplasm
        Benign Skin Fibrohistiocytic Neoplasm
        Dermatofibroma
        Skin Fibrous Histiocytoma, Cellular Variant
        Skin Fibrous Histiocytoma, Epithelioid Variant
        Skin Fibrous Histiocytoma, Fibroblastic Variant
        Skin Fibrous Histiocytoma, Histiocytic Variant
        Histiocytoma
        Benign fibrous histiocytoma
        Benign deep fibrous histiocytoma
        Fibrous Histiocytoma of Bone
        Intracranial Fibrous Histiocytoma
        Non-Ossifying Fibroma
        Malignant fibrous histiocytoma
        Abdominal Undifferentiated Pleomorphic Sarcoma
        Adult Undifferentiated Pleomorphic Sarcoma
        Cardiac Undifferentiated Pleomorphic Sarcoma
        Central Nervous System Undifferentiated Pleomorphic Sarcoma
        Childhood Undifferentiated Pleomorphic Sarcoma
        Cutaneous undifferentiated pleomorphic sarcoma
        Malignant giant cell tumor of soft parts
        Metastatic Undifferentiated Pleomorphic Sarcoma
        Penile Undifferentiated Pleomorphic Sarcoma
        Prostate Undifferentiated Pleomorphic Sarcoma
        Recurrent Undifferentiated Pleomorphic Sarcoma
        Refractory Undifferentiated Pleomorphic Sarcoma
        Resectable Undifferentiated Pleomorphic Sarcoma
        Retroperitoneal Undifferentiated Pleomorphic Sarcoma
        Sinonasal Undifferentiated Pleomorphic Sarcoma
        Undifferentiated pleomorphic sarcoma, inflammatory variant
        Unresectable Undifferentiated Pleomorphic Sarcoma
        Tenosynovial giant cell tumor, diffuse type
        Tenosynovial giant cell tumor, localized type

Professional guidelines

PubMed

Treatment Options for Multinucleate Cell Angiohistiocytoma: A Case Series and Review of the Literature.

Taibo A, Padin CP, Losada JDP, Fonseca E
J Cutan Med Surg 2023 May-Jun;27(3):219-225. Epub 2023 Mar 16 doi: 10.1177/12034754231163539. PMID: 36927096

Benign spindle cell tumors of the mammary stroma: diagnostic criteria, classification, and histogenesis.

Magro G, Michal M, Bisceglia M
Pathol Res Pract 2001;197(7):453-66. doi: 10.1078/0344-0338-00112. PMID: 11482575

Pigmented villonodular synovitis. Diagnosis and differential diagnosis.

Goldman AB, DiCarlo EF
Radiol Clin North Am 1988 Nov;26(6):1327-47. PMID: 2845469

Recent clinical studies

Diagnosis

Benign fibrous histiocytoma of the tongue.

Priya NS, Rao K, Umadevi HS, Smitha T
Indian J Dent Res 2013 Sep-Oct;24(5):635-8. doi: 10.4103/0970-9290.123419. PMID: 24355969

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