U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mixed neoplasm

MedGen UID:
234575
•Concept ID:
C1368354
•
Neoplastic Process
Synonyms: Mixed Neoplasm; mixed neoplasm; Mixed Tumor; mixed tumor; mixed tumour
 
Monarch Initiative: MONDO:0021043

Definition

A neoplasm composed of at least two distinct cellular populations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed neoplasm

Professional guidelines

PubMed

Characterization of the major histopathological components of thyroid nodules using sonographic textural features for clinical diagnosis and management.
Chen SJ, Yu SN, Tzeng JE, Chen YT, Chang KY, Cheng KS, Hsiao FT, Wei CK
Ultrasound Med Biol 2009 Feb;35(2):201-8. Epub 2008 Nov 17 doi: 10.1016/j.ultrasmedbio.2008.08.017. PMID: 19010588

Recent clinical studies

Etiology

Gonadoblastoma-Associated Mixed Gonadal Germ Cell Tumor with Dysgerminoma and Hepatoid Yolk Sac Tumor Components in 46XY Gonadal Dysgenesis.
Losada DM, Benetti-Pinto CL, Andrade LALA
J Pediatr Adolesc Gynecol 2019 Oct;32(5):558-560. Epub 2019 Jun 6 doi: 10.1016/j.jpag.2019.05.014. PMID: 31175959
Mixed Neuroendocrine-Nonneuroendocrine Neoplasms (MiNENs): Unifying the Concept of a Heterogeneous Group of Neoplasms.
La Rosa S, Sessa F, Uccella S
Endocr Pathol 2016 Dec;27(4):284-311. doi: 10.1007/s12022-016-9432-9. PMID: 27169712

Diagnosis

Cases of Yolk sac tumor associated with gynecological malignant tumor.
Wang S, Chen K, Chen Q, Huang S, Lu W
BMC Womens Health 2023 Jun 30;23(1):348. doi: 10.1186/s12905-023-02495-w. PMID: 37391759Free PMC Article
Mixed chorangioma and leiomyoma of the placenta, with a brief review of nontrophoblastic placental lesions.
Webb SD, Bonasoni MP, Palicelli A, Comitini G, Heller DS
Pediatr Dev Pathol 2022 May-Jun;25(3):316-320. Epub 2021 Oct 4 doi: 10.1177/10935266211047775. PMID: 34606386
Mixed Intraepithelial Neoplasia-Well-Differentiated Neuroendocrine Tumor of the Gallbladder: A Hitherto Unreported Combination.
Kővári B, Turkevi-Nagy S, Lauwers GY, Jiang K
Int J Surg Pathol 2021 Sep;29(6):685-689. Epub 2021 Jan 9 doi: 10.1177/1066896920986987. PMID: 33423570
Mixed Neuroendocrine-Nonneuroendocrine Neoplasms (MiNENs): Unifying the Concept of a Heterogeneous Group of Neoplasms.
La Rosa S, Sessa F, Uccella S
Endocr Pathol 2016 Dec;27(4):284-311. doi: 10.1007/s12022-016-9432-9. PMID: 27169712
Large ameloblastic fibro-odontoma in an 18-year-old girl and review of literature.
Pillai A, Moghe S, Guru KN, Nair PP
BMJ Case Rep 2012 Nov 19;2012 doi: 10.1136/bcr-2012-007160. PMID: 23166172Free PMC Article

Therapy

Aggressive papillary glioneuronal tumor: case report and literature review.
Newton HB, Dalton J, Ray-Chaudhury A, Gahbauer R, McGregor J
Clin Neuropathol 2008 Sep-Oct;27(5):317-24. doi: 10.5414/npp27317. PMID: 18808063

Prognosis

Cases of Yolk sac tumor associated with gynecological malignant tumor.
Wang S, Chen K, Chen Q, Huang S, Lu W
BMC Womens Health 2023 Jun 30;23(1):348. doi: 10.1186/s12905-023-02495-w. PMID: 37391759Free PMC Article
Mixed Intraepithelial Neoplasia-Well-Differentiated Neuroendocrine Tumor of the Gallbladder: A Hitherto Unreported Combination.
Kővári B, Turkevi-Nagy S, Lauwers GY, Jiang K
Int J Surg Pathol 2021 Sep;29(6):685-689. Epub 2021 Jan 9 doi: 10.1177/1066896920986987. PMID: 33423570
Gonadoblastoma-Associated Mixed Gonadal Germ Cell Tumor with Dysgerminoma and Hepatoid Yolk Sac Tumor Components in 46XY Gonadal Dysgenesis.
Losada DM, Benetti-Pinto CL, Andrade LALA
J Pediatr Adolesc Gynecol 2019 Oct;32(5):558-560. Epub 2019 Jun 6 doi: 10.1016/j.jpag.2019.05.014. PMID: 31175959
Fever as a first manifestation of advanced gastric adenosquamous carcinoma: a case report.
Ajoodhea H, Zhang RC, Xu XW, Jin WW, Chen K, He YT, Mou YP
World J Gastroenterol 2014 Aug 7;20(29):10193-201. doi: 10.3748/wjg.v20.i29.10193. PMID: 25110448Free PMC Article

Clinical prediction guides

Spatial distribution of CD34 protein in primordial odontogenic tumour, ameloblastic fibroma and the tooth germ.
Pereira Prado V, Landini G, Mosqueda Taylor A, Vargas P, Bologna Molina R
J Oral Pathol Med 2023 Feb;52(2):181-187. Epub 2022 Oct 17 doi: 10.1111/jop.13370. PMID: 36207782
Mixed Neuroendocrine-Nonneuroendocrine Neoplasms (MiNENs): Unifying the Concept of a Heterogeneous Group of Neoplasms.
La Rosa S, Sessa F, Uccella S
Endocr Pathol 2016 Dec;27(4):284-311. doi: 10.1007/s12022-016-9432-9. PMID: 27169712
Rosette-forming glioneuronal tumor of the fourth ventricle with advanced microvascular proliferation--a case report.
Matyja E, Grajkowska W, Nauman P, Ozieblo A, Bonicki W
Neuropathology 2011 Aug;31(4):427-32. Epub 2010 Nov 24 doi: 10.1111/j.1440-1789.2010.01168.x. PMID: 21092064
Pure and mixed Brenner tumors of the ovary: clinicopathologic and histogenetic observations.
Waxman M
Cancer 1979 May;43(5):1830-9. doi: 10.1002/1097-0142(197905)43:5<1830::aid-cncr2820430536>3.0.co;2-c. PMID: 445369

Recent systematic reviews

A systematic review on sinonasal mixed adenoneuroendocrine carcinoma.
Issa K, Smith BD, Kaplan SJ, Madden J, Jang DW, Zomorodi A, Brizel D, Abi Hachem R
Int Forum Allergy Rhinol 2021 Sep;11(9):1391-1394. Epub 2021 May 19 doi: 10.1002/alr.22811. PMID: 34013656

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On
    • Mixed neoplasm
      Mixed neoplasm
      MedGen
    • Dancing
      Dancing
      Rhythmic and patterned body movements which are usually performed to music.<br/>
      MeSH

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...