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Benign vaginal mixed epithelial and mesenchymal neoplasm

MedGen UID:
267349
•Concept ID:
C1511106
•
Neoplastic Process
Synonyms: benign vaginal carcinosarcoma; Benign Vaginal Mixed Epithelial and Mesenchymal Neoplasm; benign vaginal mixed epithelial and mesenchymal neoplasm; Benign Vaginal Mixed Epithelial and Mesenchymal Tumor; benign vaginal mixed epithelial and mesenchymal tumor; benign vaginal mixed epithelial and mesenchymal tumour
 
Monarch Initiative: MONDO:0001731

Definition

A non-metastasizing neoplasm that arises from the vagina and is characterized by the presence of benign epithelial and benign mesenchymal elements. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign vaginal mixed epithelial and mesenchymal neoplasm

Professional guidelines

PubMed

Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosis.
Oliva E, Gonzalez L, Dionigi A, Young RH
Mod Pathol 2004 Oct;17(10):1243-50. doi: 10.1038/modpathol.3800173. PMID: 15154010

Recent clinical studies

Etiology

Adenofibroma of the endometrium protruding into the vaginal cavity: findings on transvaginal ultrasonography, MRI and CT.
Konishi Y, Sato H, Fujimoto T, Tanaka H, Takahashi O, Tanaka T
J Obstet Gynaecol Res 2006 Dec;32(6):623-7. doi: 10.1111/j.1447-0756.2006.00467.x. PMID: 17100829
Benign mixed tumor of the vagina: case report with expanded immunohistochemical profile.
Murdoch F, Sharma R, Al-Nafussi A
Int J Gynecol Cancer 2003 Jul-Aug;13(4):543-7. doi: 10.1046/j.1525-1438.2003.13309.x. PMID: 12911736

Diagnosis

Metastasizing uterine mullerian adenosarcoma in a young female: Diagnostic enigma.
Patnayak R, Rukmangadha N, Architha P, Reddy GS, Lakshmi AY, Kannan T, Jena A
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18. PMID: 30004077
Benign mixed tumor of the vagina.
Song Y, Wu SG, Dong SN, Luo F, Liu KP
Eur J Gynaecol Oncol 2017;38(3):465-468. PMID: 29693894
Spindle Cell Epithelioma of the Vagina: Report of Two Cases, Literature Review, and New Immunohistochemical Markers.
Berdugo J, Gauthier P, Provencher D, Matte C, Piché J, Rahimi K
Int J Surg Pathol 2015 Dec;23(8):677-81. Epub 2015 May 20 doi: 10.1177/1066896915587920. PMID: 25998318
Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosis.
Oliva E, Gonzalez L, Dionigi A, Young RH
Mod Pathol 2004 Oct;17(10):1243-50. doi: 10.1038/modpathol.3800173. PMID: 15154010
Müllerian adenosarcoma of the uterine body: a report of nine cases.
Fox H, Harilal KR, Youell A
Histopathology 1979 May;3(3):167-80. doi: 10.1111/j.1365-2559.1979.tb02994.x. PMID: 468120

Therapy

Metastasizing uterine mullerian adenosarcoma in a young female: Diagnostic enigma.
Patnayak R, Rukmangadha N, Architha P, Reddy GS, Lakshmi AY, Kannan T, Jena A
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18. PMID: 30004077

Prognosis

Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings.
Laspas F, Roussakis A, Papadopoulos S, Fanariotis I, Kritikos N, Kehagias D
Ultrasound Obstet Gynecol 2010 May;35(5):617-9. doi: 10.1002/uog.7511. PMID: 20069660
Benign mixed tumor of the vagina: case report with expanded immunohistochemical profile.
Murdoch F, Sharma R, Al-Nafussi A
Int J Gynecol Cancer 2003 Jul-Aug;13(4):543-7. doi: 10.1046/j.1525-1438.2003.13309.x. PMID: 12911736

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