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| Status |
Public on Feb 22, 2022 |
| Title |
Targeted gene expression profiling of human myeloid cells from blood and lung compartments of patients with Tuberculosis and other lung diseases |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by RT-PCR
|
| Summary |
This was a pilot study aimed at uncovering the role of myeloid-derived suppressor cells (myeloid-derived suppressor cell) in patients with Tuberculosis and differences between cells found in peripheral blood and in the lung.
Fluidigm™ RT-PCR technology was used to quantify expression levels of 43 genes in monocytecytes and myeloid-derived suppressor cell from peripheral blood and monocytecytes and alveolar macrophages from bronchoalveolar lavage fluid taken from patients with Tuberculosis or other lung diseases.
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| Overall design |
Gene expressions levels were compared between lung and blood derived cells within and between TB patients and healthy controls
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| Contributor(s) |
Kotze LA, van der Spuy GD |
| Citation(s) |
35356003 |
| |
| Submission date |
Feb 21, 2022 |
| Last update date |
Apr 06, 2022 |
| Contact name |
Gian van der Spuy |
| Organization name |
Stellenbosch University
|
| Department |
Biomedical Sciences
|
| Street address |
Francie van Zijl Dr
|
| City |
Parow |
| ZIP/Postal code |
7530 |
| Country |
South Africa |
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| Platforms (1) |
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| Samples (84)
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| Relations |
| BioProject |
PRJNA808999 |
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