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Series GSE117285 Query DataSets for GSE117285
Status Public on Nov 12, 2020
Title Pattern of Extramammary Paget disease gene expression
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To further understand different gene expression of Extramammary Paget disease skin and normal skin, we have employed whole skin microarray expression profiling as a discovery platform to identify different genes with Extramammary Paget disease skin and normal skin.comparision with normal skin, upgene is 4572 in disease group, downgene is 6473. mTOR pathway, RAS pathway, PI3K-AKT pathway, IL6-JAK-Stat3 pathway and so on are activated, WNT Pathway is inhibited.
 
Overall design 3 normal human skin and 4 Extramammary paget disease scrotum skin were taken and Quickly put it into liquid nitrogen ,the samples were taken to lab with dry ice,RNA were extracted with trizol,Good quality RNA were explored as microarrary analysis in capitalBio technology.
 
Contributor(s) Song Y, Yu Z
Citation(s) 32457396
Submission date Jul 18, 2018
Last update date Nov 12, 2020
Contact name li na bu
E-mail(s) linabu@cau.edu.cn
Phone 18811357685
Organization name China Agricultural University
Street address NO.2 yuanmingyuan
City Beijing
ZIP/Postal code 100193
Country China
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (8)
GSM3290427 A41785
GSM3290428 A42345
GSM3290429 A42537
Relations
BioProject PRJNA481660

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE117285_RAW.tar 25.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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