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Benign Head and Neck Neoplasm

MedGen UID:
1747379
Concept ID:
C5420464
Neoplastic Process

Definition

A neoplasm that arises from the head and neck and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Head and Neck Neoplasm

Professional guidelines

PubMed

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Alexander EK, Doherty GM, Barletta JA
Lancet Diabetes Endocrinol 2022 Jul;10(7):540-548. doi: 10.1016/S2213-8587(22)00139-5. PMID: 35752201
Grani G, Sponziello M, Pecce V, Ramundo V, Durante C
J Clin Endocrinol Metab 2020 Sep 1;105(9):2869-83. doi: 10.1210/clinem/dgaa322. PMID: 32491169Free PMC Article

Recent clinical studies

Etiology

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Sandow L, Thawani R, Kim MS, Heinrich MC
Endocr Pract 2023 Feb;29(2):141-147. Epub 2022 Oct 15 doi: 10.1016/j.eprac.2022.10.002. PMID: 36252779Free PMC Article
Tufano RP, Pace-Asciak P, Russell JO, Suárez C, Randolph GW, López F, Shaha AR, Mäkitie A, Rodrigo JP, Kowalski LP, Zafereo M, Angelos P, Ferlito A
Front Endocrinol (Lausanne) 2021;12:698689. Epub 2021 Jun 24 doi: 10.3389/fendo.2021.698689. PMID: 34248853Free PMC Article
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584

Diagnosis

Zhao CX, Dombrowski ND, Perez-Atayde AR, Robson CD, Afshar S, Janeway KA, Rahbar R
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110511. Epub 2020 Nov 18 doi: 10.1016/j.ijporl.2020.110511. PMID: 33271436
Schwarz Y, Pitaro J, Waissbluth S, Daniel SJ
Int J Pediatr Otorhinolaryngol 2016 Jun;85:148-53. Epub 2016 Mar 28 doi: 10.1016/j.ijporl.2016.03.026. PMID: 27240514
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584
Ha J, Yu YC, Lannigan F
Curr Pediatr Rev 2014;10(3):238-48. doi: 10.2174/1573396309666131209210751. PMID: 25088344
Capatina C, Ntali G, Karavitaki N, Grossman AB
Endocr Relat Cancer 2013 Oct;20(5):R291-305. Epub 2013 Aug 23 doi: 10.1530/ERC-13-0223. PMID: 23921204

Therapy

Muhammad H, Santhanam P, Russell JO
Endocrine 2021 Jun;72(3):619-632. Epub 2021 Jan 15 doi: 10.1007/s12020-020-02598-6. PMID: 33449296
Livhits MJ, Zhu CY, Kuo EJ, Nguyen DT, Kim J, Tseng CH, Leung AM, Rao J, Levin M, Douek ML, Beckett KR, Cheung DS, Gofnung YA, Smooke-Praw S, Yeh MW
JAMA Oncol 2021 Jan 1;7(1):70-77. doi: 10.1001/jamaoncol.2020.5935. PMID: 33300952Free PMC Article
Sheedy T, Heaton C
JAAPA 2019 Sep;32(9):26-31. doi: 10.1097/01.JAA.0000578756.52642.cb. PMID: 31403488
Johnston J, Allen JE
Curr Opin Otolaryngol Head Neck Surg 2018 Dec;26(6):403-408. doi: 10.1097/MOO.0000000000000487. PMID: 30234659
Reiter R, Hoffmann TK, Pickhard A, Brosch S
Dtsch Arztebl Int 2015 May 8;112(19):329-37. doi: 10.3238/arztebl.2015.0329. PMID: 26043420Free PMC Article

Prognosis

Togni L, Mascitti M, Sartini D, Campagna R, Pozzi V, Salvolini E, Offidani A, Santarelli A, Emanuelli M
Biomolecules 2021 Oct 28;11(11) doi: 10.3390/biom11111594. PMID: 34827592Free PMC Article
Feygin T, Khalek N, Moldenhauer JS
Prenat Diagn 2020 Sep;40(10):1203-1219. Epub 2020 May 26 doi: 10.1002/pd.5722. PMID: 32350893
Mendenhall WM, Morris CG, Amdur RJ, Hitchcock KE, Silver NL, Dziegielewski PT
Head Neck 2019 Jul;41(7):2107-2110. Epub 2019 Feb 19 doi: 10.1002/hed.25664. PMID: 30779406
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Mack MG, Rieger J, Baghi M, Bisdas S, Vogl TJ
Eur J Radiol 2008 Jun;66(3):493-500. Epub 2008 Mar 11 doi: 10.1016/j.ejrad.2008.01.019. PMID: 18337039

Clinical prediction guides

Saoud C, Bailey GE, Graham A, Bonilla LM, Sanchez SI, Maleki Z
Acta Cytol 2024;68(3):194-205. Epub 2024 Feb 28 doi: 10.1159/000538069. PMID: 38417405
Sandow L, Thawani R, Kim MS, Heinrich MC
Endocr Pract 2023 Feb;29(2):141-147. Epub 2022 Oct 15 doi: 10.1016/j.eprac.2022.10.002. PMID: 36252779Free PMC Article
Zhao CX, Dombrowski ND, Perez-Atayde AR, Robson CD, Afshar S, Janeway KA, Rahbar R
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110511. Epub 2020 Nov 18 doi: 10.1016/j.ijporl.2020.110511. PMID: 33271436
Steward DL, Carty SE, Sippel RS, Yang SP, Sosa JA, Sipos JA, Figge JJ, Mandel S, Haugen BR, Burman KD, Baloch ZW, Lloyd RV, Seethala RR, Gooding WE, Chiosea SI, Gomes-Lima C, Ferris RL, Folek JM, Khawaja RA, Kundra P, Loh KS, Marshall CB, Mayson S, McCoy KL, Nga ME, Ngiam KY, Nikiforova MN, Poehls JL, Ringel MD, Yang H, Yip L, Nikiforov YE
JAMA Oncol 2019 Feb 1;5(2):204-212. doi: 10.1001/jamaoncol.2018.4616. PMID: 30419129Free PMC Article
Ha J, Yu YC, Lannigan F
Curr Pediatr Rev 2014;10(3):238-48. doi: 10.2174/1573396309666131209210751. PMID: 25088344

Recent systematic reviews

Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Muhammad H, Santhanam P, Russell JO
Endocrine 2021 Jun;72(3):619-632. Epub 2021 Jan 15 doi: 10.1007/s12020-020-02598-6. PMID: 33449296
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Attlmayr B, Derbyshire SG, Kasbekar AV, Swift AC
J Laryngol Otol 2017 Apr;131(4):284-289. Epub 2017 Feb 9 doi: 10.1017/S0022215117000172. PMID: 28179032
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

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