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Unusual CNS infection

MedGen UID:: 1684837
•Concept ID:: C4759823
•: Disease or Syndrome

Synonyms:	Central nervous system infection; central nervous system infection; central nervous system infectious disease; central nervous system infectious disorder; infections, central nervous system; infectious disease of central nervous system

HPO:	HP:0011450
Monarch Initiative:	MONDO:0024619

Definition

A type of infection of the central nervous system that can be regarded as a sign of a pathological susceptibility to infection. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVUnusual CNS infection

Phenotypic abnormality
- Abnormality of the immune system
  - Abnormality of immune system physiology
    - Unusual infection
      - Unusual infection by anatomical site
        Unusual CNS infection
        Infectious encephalitis
        Bacterial encephalitis
        Viral encephalitis
        Acute hemorrhagic encephalitis
        Acute necrotizing encephalitis
        Acute necrotizing encephalopathy of childhood
        Arthropod-borne viral encephalitis, vector unknown
        Colorado tick fever
        COVID-19-Associated Encephalitis
        Eastern equine encephalitis
        EBV encephalitis
        Encephalitis lethargica
        Encephalomyelitis, Equine
        Enteroviral encephalitis
        Hendra virus infection
        Herpes simplex encephalitis
        Japanese encephalitis virus disease
        Kluver-Bucy syndrome
        La Crosse encephalitis
        Mosquito-borne viral encephalitis
        Mycoplasma encephalitis
        Nipah virus disease
        Postvaricella encephalitis
        Progressive multifocal leukoencephalopathy
        Progressive rubella panencephalitis
        St. Louis encephalitis
        Subacute sclerosing panencephalitis
        Tick-borne encephalitis
        West-Nile encephalitis
        Western equine encephalitis
        Meningitis
        Arachnoiditis
        Spinal arachnoiditis
        Aseptic meningitis
        Bacterial meningitis
        Escherichia coli meningitis
        H influenze type B Meningitis
        Haemophilus meningitis
        Listeria meningitis
        Meningococcal meningitis
        Pneumococcal meningitis
        Tuberculosis of meninges
        Chronic lymphocytic meningitis
        Eosinophilic meningitis
        Fungal meningitis
        Coccidioidal meningitis
        Cryptococcal meningitis
        Infectious meningitis
        Viral meningitis
        Lymphocytic choriomeningitis
        Meningoencephalitis
        Central nervous system lupus
        Infectious Meningoencephalitis
        Recurrent meningitis
        Recurrent bacterial meningitis

Professional guidelines

PubMed

Treatment for paraneoplastic neuropathies.

Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647

Diagnosis and treatment of viral encephalitis.

Chaudhuri A, Kennedy PG
Postgrad Med J 2002 Oct;78(924):575-83. doi: 10.1136/pmj.78.924.575. PMID: 12415078 Free PMC Article

Evaluation and treatment of vasculitis in the critically ill patient.

Merkel PA, Choi HK, Niles JL
Crit Care Clin 2002 Apr;18(2):321-44. doi: 10.1016/s0749-0704(01)00006-9. PMID: 12053837

See all (21)

Recent clinical studies

Etiology

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis.

Gövert F, Abrante L, Becktepe J, Balint B, Ganos C, Hofstadt-van Oy U, Krogias C, Varley J, Irani SR, Paneva S, Titulaer MJ, de Vries JM, Boon AJW, Schreurs MWJ, Joubert B, Honnorat J, Vogrig A, Ariño H, Sabater L, Dalmau J, Scotton S, Jacob S, Melzer N, Bien CG, Geis C, Lewerenz J, Prüss H, Wandinger KP, Deuschl G, Leypoldt F
Brain 2023 Feb 13;146(2):657-667. doi: 10.1093/brain/awac276. PMID: 35875984

Infections.

Hunter JV, Goerner L
Handb Clin Neurol 2016;136:1173-98. doi: 10.1016/B978-0-444-53486-6.00061-2. PMID: 27430464

Treatment for paraneoplastic neuropathies.

Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647

Pathogenic flaviviruses.

Gould EA, Solomon T
Lancet 2008 Feb 9;371(9611):500-9. doi: 10.1016/S0140-6736(08)60238-X. PMID: 18262042

Prion diseases.

Korczyn AD
Curr Opin Neurol 1997 Jun;10(3):273-81. doi: 10.1097/00019052-199706000-00018. PMID: 9229138

See all (421)

Diagnosis

Bacterial Infections of the Central Nervous System.

LaPenna PA, Roos KL
Semin Neurol 2019 Jun;39(3):334-342. Epub 2019 Aug 2 doi: 10.1055/s-0039-1693159. PMID: 31378869

Infectious encephalitis: mimics and chameleons.

Toledano M, Davies NWS
Pract Neurol 2019 Jun;19(3):225-237. Epub 2019 Mar 16 doi: 10.1136/practneurol-2018-002114. PMID: 30878971

Human transmissible spongiform encephalopathies: historic view.

Asher DM, Gregori L
Handb Clin Neurol 2018;153:1-17. doi: 10.1016/B978-0-444-63945-5.00001-5. PMID: 29887130

Sporadic and Infectious Human Prion Diseases.

Will RG, Ironside JW
Cold Spring Harb Perspect Med 2017 Jan 3;7(1) doi: 10.1101/cshperspect.a024364. PMID: 27793965 Free PMC Article

Prion diseases.

Korczyn AD
Curr Opin Neurol 1997 Jun;10(3):273-81. doi: 10.1097/00019052-199706000-00018. PMID: 9229138

See all (1354)

Therapy

Bacterial Infections of the Central Nervous System.

LaPenna PA, Roos KL
Semin Neurol 2019 Jun;39(3):334-342. Epub 2019 Aug 2 doi: 10.1055/s-0039-1693159. PMID: 31378869

Rickettsial meningitis.

Salva I, de Sousa R, Gouveia C
BMJ Case Rep 2014 Mar 10;2014 doi: 10.1136/bcr-2013-203283. PMID: 24614778 Free PMC Article

Unusual reactions to insect stings.

Reisman RE
Curr Opin Allergy Clin Immunol 2005 Aug;5(4):355-8. doi: 10.1097/01.all.0000173782.35283.b6. PMID: 15985819

Rhinoorbitocerebral actinomycosis.

Nithyanandam S, D'Souza O, Rao SS, Battu RR, George S
Ophthalmic Plast Reconstr Surg 2001 Mar;17(2):134-6. doi: 10.1097/00002341-200103000-00012. PMID: 11281588

The tetracyclines.

Cunha BA, Comer JB, Jonas M
Med Clin North Am 1982 Jan;66(1):293-302. doi: 10.1016/s0025-7125(16)31461-4. PMID: 7038336

See all (703)

Prognosis

Lyme Disease in Humans.

Radolf JD, Strle K, Lemieux JE, Strle F
Curr Issues Mol Biol 2021;42:333-384. Epub 2020 Dec 11 doi: 10.21775/cimb.042.333. PMID: 33303701 Free PMC Article

Prion disease and the 'protein-only hypothesis'.

Ma J, Wang F
Essays Biochem 2014;56:181-91. doi: 10.1042/bse0560181. PMID: 25131595 Free PMC Article

Autoimmune-mediated encephalitis.

Demaerel P, Van Dessel W, Van Paesschen W, Vandenberghe R, Van Laere K, Linn J
Neuroradiology 2011 Nov;53(11):837-51. Epub 2011 Jan 27 doi: 10.1007/s00234-010-0832-0. PMID: 21271243

Understanding Creutzfeldt-Jakob disease.

Nguyen ST, Rickman LS
J Gerontol Nurs 1997 Nov;23(11):22-7; quiz 55. doi: 10.3928/0098-9134-19971101-10. PMID: 9416053

Bone marrow necrosis.

Ranaghan L, Morris TC, Desai ZR, Markey GM
Am J Hematol 1994 Nov;47(3):225-8. doi: 10.1002/ajh.2830470314. PMID: 7942788

See all (497)

Clinical prediction guides

Spinal epidural abscess in COVID-19 patients.

Talamonti G, Colistra D, Crisà F, Cenzato M, Giorgi P, D'Aliberti G
J Neurol 2021 Jul;268(7):2320-2326. Epub 2020 Sep 10 doi: 10.1007/s00415-020-10211-z. PMID: 32910251 Free PMC Article

Neurologic complications in renal transplantation.

Potluri K, Holt D, Hou S
Handb Clin Neurol 2014;121:1245-55. doi: 10.1016/B978-0-7020-4088-7.00084-5. PMID: 24365416

Treatment for paraneoplastic neuropathies.

Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647

DOCK8 deficiency.

Su HC, Jing H, Zhang Q
Ann N Y Acad Sci 2011 Dec;1246:26-33. doi: 10.1111/j.1749-6632.2011.06295.x. PMID: 22236427

Autoimmune-mediated encephalitis.

Demaerel P, Van Dessel W, Van Paesschen W, Vandenberghe R, Van Laere K, Linn J
Neuroradiology 2011 Nov;53(11):837-51. Epub 2011 Jan 27 doi: 10.1007/s00234-010-0832-0. PMID: 21271243

See all (260)

Recent systematic reviews

Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalitis Following COVID-19: Systematic Review and Meta-synthesis.

Manzano GS, McEntire CRS, Martinez-Lage M, Mateen FJ, Hutto SK
Neurol Neuroimmunol Neuroinflamm 2021 Nov;8(6) Epub 2021 Aug 27 doi: 10.1212/NXI.0000000000001080. PMID: 34452974 Free PMC Article

Skin nontuberculous mycobacterial infection in systemic lupus erythematosus: an unusual skin infection mimicking lupus vasculitis.

Touma Z, Haddad A, Gladman DD, Uleryk EM, Urowitz MB
Semin Arthritis Rheum 2013 Apr;42(5):498-506. Epub 2013 Jan 16 doi: 10.1016/j.semarthrit.2012.08.002. PMID: 23332736

Treatment for paraneoplastic neuropathies.

Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647

See all (3)

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Unusual CNS infection

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

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Table of contents

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Practice guidelines

Consumer resources

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