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Adnexal Diseases

MedGen UID:: 1763
•Concept ID:: C0001576
•: Disease or Syndrome

Synonyms:

Adnexal Disease; Disease, Adnexal; Diseases, Adnexal

Definition

Diseases of the uterine appendages (ADNEXA UTERI) including diseases involving the OVARY, the FALLOPIAN TUBES, and ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT). [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAdnexal Diseases

Pathological process
- Disease
  - Disorder by Site
    - Disorder of the genitourinary system
      - Diseases, Genital
        Disorder of female genital system
        Adnexal Diseases
        Disorder of ovary
        Anovulation
        Anovulatory
        Oophoritis
        Ovarian cyst
        Benign Ovarian Cyst
        Calcified ovarian cyst
        Hemorrhagic ovarian cyst
        Ovarian Endometriotic Cyst
        Ovarian serous cystadenoma
        Polycystic ovaries
        Unilocular ovarian cyst
        Ovarian hyperstimulation syndrome
        Ovarian neoplasm
        Brenner Tumor
        Endometrioid carcinoma
        Familial ovarian carcinoma
        Fibroma of ovary
        Granulosa cell tumor
        Hereditary breast ovarian cancer syndrome
        Maligant granulosa cell tumor of ovary
        Meigs syndrome
        Ovarian benign neoplasm
        Ovarian cancer
        OVARIAN CANCER, EPITHELIAL, SOMATIC
        Ovarian carcinoma
        Ovarian cystadenoma
        Ovarian epithelial tumor
        Ovarian germ cell tumor
        Ovarian gonadoblastoma
        Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor
        Ovarian neuroendocrine neoplasm
        Ovarian papillary adenocarcinoma
        Ovarian sex cord-stromal tumor
        Ovarian Soft Tissue Neoplasm
        Ovarian Stromal Luteoma
        Ovarian teratoma
        Sertoli-Leydig cell tumor
        Thecoma
        Ovarian Non-Neoplastic Disorder
        Leuteoma of Pregnancy
        Menstrual problem
        Ovarian endometriosis
        ovarian failure
        Ovarian Fibromatosis and Massive Edema
        Ovarian Stromal Hyperplasia
        Ovarian stromal hyperthecosis
        Ovarian torsion
        Resistant ovary syndrome
        Premature ovarian failure
        Premature ovarian failure 1
        Premature ovarian failure 3
        Premature ovarian failure 4
        Premature ovarian failure 5
        Premature ovarian failure 6
        Premature ovarian failure 7
        Premature ovarian failure 2A
        Premature ovarian failure 2B
        Premature ovarian insufficiency
        Fallopian tube disorder
        Fallopian Tube Non-Neoplastic Disorder
        Fallopian tube endometriosis
        Fallopian Tube Metaplastic Papillary Lesion
        Placental Site Nodule and Plaque Occurring in the Fallopian Tube
        Pyosalpinx
        Salpingitis
        Neoplasm of fallopian tube
        Borderline Fallopian Tube Neoplasm
        Fallopian tube benign neoplasm
        Fallopian tube cancer
        Fallopian tube endometrioid tumor
        Fallopian tube germ cell tumor
        Fallopian tube mucinous tumor
        Fallopian Tube Serous Neoplasm
        Fallopian Tube Soft Tissue Neoplasm
        Pelvic inflammatory disease
        Adnexitis
        Salpingo-oophoritis
        AIDS-Related Pelvic Inflammatory Disease
        Endometritis
        Acute endometritis
        Chronic endometritis
        Post-Abortion Endometritis
        Puerperal endometritis
        Parametritis

Professional guidelines

PubMed

Molecular changes driving low-grade serous ovarian cancer and implications for treatment.

Kelliher L, Yoeli-Bik R, Schweizer L, Lengyel E
Int J Gynecol Cancer 2024 Oct 7;34(10):1630-1638. doi: 10.1136/ijgc-2024-005305. PMID: 38950921 Free PMC Article

Criteria for selection of laparoscopy for women with adnexal mass.

Barreta A, Sallum LF, Sarian LO, Bastos JF, Derchain S
JSLS 2014 Jul-Sep;18(3) doi: 10.4293/JSLS.2014.00215. PMID: 25392617 Free PMC Article

Guidelines for drug treatment of male infertility.

Haidl G, Schill WB
Drugs 1991 Jan;41(1):60-8. doi: 10.2165/00003495-199141010-00006. PMID: 1706988

See all (5)

Recent clinical studies

Etiology

Scarless preventive surgery.

Rathat G, Blay L, Bakenga J, Roggen N, Peralta G, Baekelandt J
Int J Gynaecol Obstet 2023 Nov;163(2):701-702. Epub 2023 Aug 7 doi: 10.1002/ijgo.15039. PMID: 37548070

Adnexal Masses in Adolescents.

Northridge JL
Pediatr Ann 2020 Apr 1;49(4):e183-e187. doi: 10.3928/19382359-20200227-01. PMID: 32275763

Imaging of Adnexal Masses.

Thakur M, Timmerman D
Clin Obstet Gynecol 2017 Mar;60(1):38-45. doi: 10.1097/GRF.0000000000000261. PMID: 28005597

Re-torsion of the ovaries.

Hyttel TE, Bak GS, Larsen SB, Løkkegaard EC
Acta Obstet Gynecol Scand 2015 Mar;94(3):236-44. Epub 2014 Dec 11 doi: 10.1111/aogs.12542. PMID: 25412114

Adnexal torsion.

Oelsner G, Shashar D
Clin Obstet Gynecol 2006 Sep;49(3):459-63. doi: 10.1097/00003081-200609000-00006. PMID: 16885653

See all (938)

Diagnosis

Adnexal Masses in Adolescents.

Northridge JL
Pediatr Ann 2020 Apr 1;49(4):e183-e187. doi: 10.3928/19382359-20200227-01. PMID: 32275763

Adnexal Masses in Pregnancy.

McMinn E, Schwartz N
Clin Obstet Gynecol 2020 Jun;63(2):392-404. doi: 10.1097/GRF.0000000000000528. PMID: 32167949

Adnexal Torsion.

Adeyemi-Fowode O, McCracken KA, Todd NJ
J Pediatr Adolesc Gynecol 2018 Aug;31(4):333-338. Epub 2018 Apr 11 doi: 10.1016/j.jpag.2018.03.010. PMID: 29653167

Imaging of Adnexal Masses.

Thakur M, Timmerman D
Clin Obstet Gynecol 2017 Mar;60(1):38-45. doi: 10.1097/GRF.0000000000000261. PMID: 28005597

Practice Bulletin No. 174: Evaluation and Management of Adnexal Masses.

American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Gynecology
Obstet Gynecol 2016 Nov;128(5):e210-e226. doi: 10.1097/AOG.0000000000001768. PMID: 27776072

See all (1347)

Therapy

The dark side of the moon: the immune-mediated adverse events of IL-17A/IL-17R inhibition.

Messina F, Piaserico S
J Dermatolog Treat 2022 Aug;33(5):2443-2454. Epub 2022 Apr 8 doi: 10.1080/09546634.2022.2062281. PMID: 35393910

Guideline No. 403: Initial Investigation and Management of Adnexal Masses.

Salvador S, Scott S, Glanc P, Eiriksson L, Jang JH, Sebastianelli A, Dean E
J Obstet Gynaecol Can 2020 Aug;42(8):1021-1029.e3. doi: 10.1016/j.jogc.2019.08.044. PMID: 32736853

Risk of complications in patients with conservatively managed ovarian tumours (IOTA5): a 2-year interim analysis of a multicentre, prospective, cohort study.

Froyman W, Landolfo C, De Cock B, Wynants L, Sladkevicius P, Testa AC, Van Holsbeke C, Domali E, Fruscio R, Epstein E, Dos Santos Bernardo MJ, Franchi D, Kudla MJ, Chiappa V, Alcazar JL, Leone FPG, Buonomo F, Hochberg L, Coccia ME, Guerriero S, Deo N, Jokubkiene L, Kaijser J, Coosemans A, Vergote I, Verbakel JY, Bourne T, Van Calster B, Valentin L, Timmerman D
Lancet Oncol 2019 Mar;20(3):448-458. Epub 2019 Feb 5 doi: 10.1016/S1470-2045(18)30837-4. PMID: 30737137

Re-torsion of the ovaries.

Hyttel TE, Bak GS, Larsen SB, Løkkegaard EC
Acta Obstet Gynecol Scand 2015 Mar;94(3):236-44. Epub 2014 Dec 11 doi: 10.1111/aogs.12542. PMID: 25412114

Adnexal torsion: review of the literature.

Sasaki KJ, Miller CE
J Minim Invasive Gynecol 2014 Mar-Apr;21(2):196-202. Epub 2013 Oct 12 doi: 10.1016/j.jmig.2013.09.010. PMID: 24126258

See all (262)

Prognosis

Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.

Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423

ESGO/ISUOG/IOTA/ESGE Consensus Statement on preoperative diagnosis of ovarian tumors.

Timmerman D, Planchamp F, Bourne T, Landolfo C, du Bois A, Chiva L, Cibula D, Concin N, Fischerova D, Froyman W, Gallardo G, Lemley B, Loft A, Mereu L, Morice P, Querleu D, Testa AC, Vergote I, Vandecaveye V, Scambia G, Fotopoulou C
Ultrasound Obstet Gynecol 2021 Jul;58(1):148-168. Epub 2021 Jun 10 doi: 10.1002/uog.23635. PMID: 33794043

Guideline No. 403: Initial Investigation and Management of Adnexal Masses.

Salvador S, Scott S, Glanc P, Eiriksson L, Jang JH, Sebastianelli A, Dean E
J Obstet Gynaecol Can 2020 Aug;42(8):1021-1029.e3. doi: 10.1016/j.jogc.2019.08.044. PMID: 32736853

Imaging of Adnexal Masses.

Thakur M, Timmerman D
Clin Obstet Gynecol 2017 Mar;60(1):38-45. doi: 10.1097/GRF.0000000000000261. PMID: 28005597

Simple ultrasound-based rules for the diagnosis of ovarian cancer.

Timmerman D, Testa AC, Bourne T, Ameye L, Jurkovic D, Van Holsbeke C, Paladini D, Van Calster B, Vergote I, Van Huffel S, Valentin L
Ultrasound Obstet Gynecol 2008 Jun;31(6):681-90. doi: 10.1002/uog.5365. PMID: 18504770

See all (519)

Clinical prediction guides

Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.

Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423

O-RADS MRI Risk Stratification System: Guide for Assessing Adnexal Lesions from the ACR O-RADS Committee.

Sadowski EA, Thomassin-Naggara I, Rockall A, Maturen KE, Forstner R, Jha P, Nougaret S, Siegelman ES, Reinhold C
Radiology 2022 Apr;303(1):35-47. Epub 2022 Jan 18 doi: 10.1148/radiol.204371. PMID: 35040672 Free PMC Article

Guideline No. 403: Initial Investigation and Management of Adnexal Masses.

Salvador S, Scott S, Glanc P, Eiriksson L, Jang JH, Sebastianelli A, Dean E
J Obstet Gynaecol Can 2020 Aug;42(8):1021-1029.e3. doi: 10.1016/j.jogc.2019.08.044. PMID: 32736853

Imaging of Adnexal Masses.

Thakur M, Timmerman D
Clin Obstet Gynecol 2017 Mar;60(1):38-45. doi: 10.1097/GRF.0000000000000261. PMID: 28005597

Simple ultrasound-based rules for the diagnosis of ovarian cancer.

See all (579)

Recent systematic reviews

Systematic Review and Meta-Analysis of O-RADS Ultrasound and O-RADS MRI for Risk Assessment of Ovarian and Adnexal Lesions.

Zhang Q, Dai X, Li W
AJR Am J Roentgenol 2023 Jul;221(1):21-33. Epub 2023 Feb 1 doi: 10.2214/AJR.22.28396. PMID: 36722758

O-RADS MRI: A Systematic Review and Meta-Analysis of Diagnostic Performance and Category-wise Malignancy Rates.

Rizzo S, Cozzi A, Dolciami M, Del Grande F, Scarano AL, Papadia A, Gui B, Gandolfo N, Catalano C, Manganaro L
Radiology 2023 Apr;307(1):e220795. Epub 2022 Nov 22 doi: 10.1148/radiol.220795. PMID: 36413127

Diagnostic accuracy of ultrasound signs for detecting adnexal torsion: systematic review and meta-analysis.

Garde I, Paredes C, Ventura L, Pascual MA, Ajossa S, Guerriero S, Vara J, Linares M, Alcázar JL
Ultrasound Obstet Gynecol 2023 Mar;61(3):310-324. Epub 2023 Feb 11 doi: 10.1002/uog.24976. PMID: 35751902

Surgical Management of Adnexal Masses in Pregnancy: A Systematic Review and Meta-analysis.

Cagino K, Li X, Thomas C, Delgado D, Christos P, Acholonu U Jr
J Minim Invasive Gynecol 2021 Jun;28(6):1171-1182.e2. Epub 2021 Jan 28 doi: 10.1016/j.jmig.2021.01.020. PMID: 33515746

Single-Port Laparoscopy vs Conventional Laparoscopy in Benign Adnexal Diseases: A Systematic Review and Meta-Analysis.

Schmitt A, Crochet P, Knight S, Tourette C, Loundou A, Agostini A
J Minim Invasive Gynecol 2017 Nov-Dec;24(7):1083-1095. Epub 2017 Jul 10 doi: 10.1016/j.jmig.2017.07.001. PMID: 28705751

See all (24)

MedGen

National Center for Biotechnology Information

Send to:

Adnexal Diseases

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity