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Meigs syndrome

MedGen UID:
6287
Concept ID:
C0025184
Neoplastic Process
Synonyms: Meig Syndrome; Meig's Syndrome; Meigs Syndrome; Meigs' Syndrome
SNOMED CT: Meigs' syndrome (63402005); Ovarian-ascites-pleural effusion syndrome (63402005); Demons-Meigs syndrome (63402005); Meigs-Cass syndrome (63402005); Meigs syndrome (63402005)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0017799
Orphanet: ORPHA314451

Definition

Meigs syndrome is a rare neoplastic disease characterized by the clinical triad of benign ovarian tumor (typically, ovarian fibroma or fibroma-like tumor), hydrothorax and ascites, which resolve after tumor resection. Patients usually present with dyspnea, pelvic mass with or without a tender, distended abdomen and/or weight loss. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMeigs syndrome
Follow this link to review classifications for Meigs syndrome in Orphanet.

Professional guidelines

PubMed

Hivert MF, Grant RW, Shrader P, Meigs JB
BMC Health Serv Res 2009 Sep 22;9:170. doi: 10.1186/1472-6963-9-170. PMID: 19772639Free PMC Article
Hivert MF, Warner AS, Shrader P, Grant RW, Meigs JB
Diabetes Care 2009 Oct;32(10):1820-2. Epub 2009 Jul 10 doi: 10.2337/dc09-0720. PMID: 19592631Free PMC Article
Cheng MH, Yen MS, Chao KC, Sheu BC, Wang PH
Taiwan J Obstet Gynecol 2008 Dec;47(4):384-90. doi: 10.1016/S1028-4559(09)60003-6. PMID: 19126502

Recent clinical studies

Etiology

Li S, Hong R, Yin M, Zhang X, Zhang T, Yang J
Acta Oncol 2023 Aug;62(8):889-896. Epub 2023 Jun 30 doi: 10.1080/0284186X.2023.2226798. PMID: 37391865
Shang W, Wu L, Xu R, Chen X, Yao S, Huang P, Wang F
Front Med 2021 Feb;15(1):116-124. Epub 2020 Jul 10 doi: 10.1007/s11684-019-0732-6. PMID: 32651935
Baloch S, Khaskheli M, Khushk IA, Farooq S
J Coll Physicians Surg Pak 2006 Sep;16(9):602-3. PMID: 16945236
Kirschner PA
Chest Surg Clin N Am 1998 May;8(2):449-72. PMID: 9619316
Young RH
Am J Surg Pathol 1993 Dec;17(12):1210-24. doi: 10.1097/00000478-199312000-00002. PMID: 7694512

Diagnosis

Fernandez Diaz JJ, Navarro Desentre L
N Engl J Med 2024 Jun 13;390(22):2107. Epub 2024 Jun 8 doi: 10.1056/NEJMicm2313447. PMID: 38856181
Kristková L, Zvaríková M, Bílek O, Dufek D, Poprach A, Holánek M
Klin Onkol 2022 Spring;35(3):232-234. doi: 10.48095/ccko2022232. PMID: 35760576
Argento AC, Gillespie CT
Semin Respir Crit Care Med 2019 Jun;40(3):402-409. Epub 2019 Sep 16 doi: 10.1055/s-0039-1695050. PMID: 31525815
Quinlan DJ
J Obstet Gynaecol Can 2012 Apr;34(4):311. doi: 10.1016/s1701-2163(16)35204-5. PMID: 22472326
Solomon S, Farber SJ, Caruso LJ
JAMA 1971 May 10;216(6):1036-7. doi: 10.1001/jama.1971.03180320078024. PMID: 5108250

Therapy

He J, Li J, Fan B, Yan L, Ouyang L
J Obstet Gynaecol Res 2023 Aug;49(8):2199-2204. Epub 2023 May 17 doi: 10.1111/jog.15677. PMID: 37199068
Liu Y, Tian Y, Zhang Y
J Pediatr Adolesc Gynecol 2022 Jun;35(3):407-409. Epub 2022 Jan 13 doi: 10.1016/j.jpag.2021.12.020. PMID: 35032667
Horino T, Ogasawara M, Kashio T, Inotani S, Ishihara M, Ohnishi H, Komori M, Ichii O, Terada Y
Rom J Intern Med 2022 Mar 1;60(1):85-89. Epub 2022 Mar 17 doi: 10.2478/rjim-2021-0032. PMID: 34333880
Yang ST, Cheng M, Lai CR, Shen SH, Lee WL, Wang PH
Taiwan J Obstet Gynecol 2021 Nov;60(6):1116-1120. doi: 10.1016/j.tjog.2021.09.028. PMID: 34794749
Torres Jiménez AR, Solís-Vallejo E, Céspedes-Cruz AI, Zeferino Cruz M, Rojas-Curiel EZ, Sánchez-Jara B
Reumatol Clin (Engl Ed) 2019 Sep-Oct;15(5):e41-e43. Epub 2017 May 15 doi: 10.1016/j.reuma.2017.04.003. PMID: 28522234

Prognosis

Iavarone I, Padovano M, Pasanisi F, Della Corte L, La Mantia E, Ronsini C
Medicina (Kaunas) 2023 Sep 19;59(9) doi: 10.3390/medicina59091684. PMID: 37763803Free PMC Article
Li S, Hong R, Yin M, Zhang X, Zhang T, Yang J
Acta Oncol 2023 Aug;62(8):889-896. Epub 2023 Jun 30 doi: 10.1080/0284186X.2023.2226798. PMID: 37391865
Kristková L, Zvaríková M, Bílek O, Dufek D, Poprach A, Holánek M
Klin Onkol 2022 Spring;35(3):232-234. doi: 10.48095/ccko2022232. PMID: 35760576
Krenke R, Maskey-Warzechowska M, Korczynski P, Zielinska-Krawczyk M, Klimiuk J, Chazan R, Light RW
Medicine (Baltimore) 2015 Dec;94(49):e2114. doi: 10.1097/MD.0000000000002114. PMID: 26656338Free PMC Article
Baloch S, Khaskheli M, Khushk IA, Farooq S
J Coll Physicians Surg Pak 2006 Sep;16(9):602-3. PMID: 16945236

Clinical prediction guides

Li S, Hong R, Yin M, Zhang X, Zhang T, Yang J
Acta Oncol 2023 Aug;62(8):889-896. Epub 2023 Jun 30 doi: 10.1080/0284186X.2023.2226798. PMID: 37391865
Brillantino C, Errico ME, Minelli R, Esposito F, Pirisi P, Gaglione G, Grella MG, Ferrara D, Zeccolini M, Rossi E
Ann Ital Chir 2022 Jul 25;11 PMID: 36606361
Chao YH, Chen HY
J Formos Med Assoc 2022 Dec;121(12):2633-2638. Epub 2022 Apr 19 doi: 10.1016/j.jfma.2022.03.020. PMID: 35459608
Amaratunga T, Millo N, Gordon V, Blcamumpaka C, Yan Y, Sparkes S, Goubran A
Ultrasound Q 2018 Mar;34(1):23-28. doi: 10.1097/RUQ.0000000000000334. PMID: 29194291
Brun JL
Gynecol Oncol 2007 Jun;105(3):796-800. Epub 2007 Apr 11 doi: 10.1016/j.ygyno.2007.01.050. PMID: 17433421

Recent systematic reviews

Krenke R, Maskey-Warzechowska M, Korczynski P, Zielinska-Krawczyk M, Klimiuk J, Chazan R, Light RW
Medicine (Baltimore) 2015 Dec;94(49):e2114. doi: 10.1097/MD.0000000000002114. PMID: 26656338Free PMC Article
Brun JL
Gynecol Oncol 2007 Jun;105(3):796-800. Epub 2007 Apr 11 doi: 10.1016/j.ygyno.2007.01.050. PMID: 17433421

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