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Abnormal circulating metabolite concentration

MedGen UID:
1701080
Concept ID:
C5139177
Finding
HPO: HP:0032180

Definition

An abnormal level of an analyte measured in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating metabolite concentration

Professional guidelines

PubMed

Olofsson P
Am J Obstet Gynecol 2023 May;228(5S):S1222-S1240. Epub 2023 Mar 19 doi: 10.1016/j.ajog.2022.07.001. PMID: 37164495
Christensen MH, Pedersen EK, Nordbø Y, Varhaug JE, Midttun Ø, Ueland PM, Nygård OK, Mellgren G, Lien EA
J Intern Med 2012 Dec;272(6):583-91. Epub 2012 Aug 5 doi: 10.1111/j.1365-2796.2012.02570.x. PMID: 22757621
Heaton A, Johnston DG, Haigh JW, Ward MK, Alberti KG, Kerr DN
Clin Sci (Lond) 1985 Oct;69(4):449-57. doi: 10.1042/cs0690449. PMID: 4042546

Recent clinical studies

Etiology

Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Olofsson P
Am J Obstet Gynecol 2023 May;228(5S):S1222-S1240. Epub 2023 Mar 19 doi: 10.1016/j.ajog.2022.07.001. PMID: 37164495
Hannan FM, Newey PJ, Whyte MP, Thakker RV
Br J Clin Pharmacol 2019 Jun;85(6):1147-1160. Epub 2018 Nov 28 doi: 10.1111/bcp.13803. PMID: 30357886Free PMC Article
Geyer J, Bakhaus K, Bernhardt R, Blaschka C, Dezhkam Y, Fietz D, Grosser G, Hartmann K, Hartmann MF, Neunzig J, Papadopoulos D, Sánchez-Guijo A, Scheiner-Bobis G, Schuler G, Shihan M, Wrenzycki C, Wudy SA, Bergmann M
J Steroid Biochem Mol Biol 2017 Sep;172:207-221. Epub 2016 Jul 5 doi: 10.1016/j.jsbmb.2016.07.002. PMID: 27392637
Wiebe VJ, Sipila PE
Crit Rev Oncol Hematol 1994 Apr;16(2):75-112. doi: 10.1016/1040-8428(94)90043-4. PMID: 8068213

Diagnosis

Olofsson P
Am J Obstet Gynecol 2023 May;228(5S):S1222-S1240. Epub 2023 Mar 19 doi: 10.1016/j.ajog.2022.07.001. PMID: 37164495
Hannan FM, Newey PJ, Whyte MP, Thakker RV
Br J Clin Pharmacol 2019 Jun;85(6):1147-1160. Epub 2018 Nov 28 doi: 10.1111/bcp.13803. PMID: 30357886Free PMC Article
Shackleton C, Malunowicz E
Steroids 2003 Oct;68(9):707-17. doi: 10.1016/s0039-128x(03)00115-6. PMID: 14625002
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400
Duncan JS
Brain 1997 Feb;120 ( Pt 2):339-77. doi: 10.1093/brain/120.2.339. PMID: 9117380

Therapy

Cordina J, Ahmad I, Nath R, Abdul Rahim B, Van A, Al-Zuhairi D, Williams K, Pont L, Catanzariti R, Mehndiratta S, Valdivia-Olivares RY, De Rubis G, Dua K
Naunyn Schmiedebergs Arch Pharmacol 2024 Oct;397(10):7297-7306. Epub 2024 May 8 doi: 10.1007/s00210-024-03140-5. PMID: 38717707Free PMC Article
Tylutki Z, Jawień W, Ciszowski K, Wilimowska J, Anand JS
Toxicol Mech Methods 2015 Jan;25(1):1-12. Epub 2014 Oct 21 doi: 10.3109/15376516.2014.971137. PMID: 25264211
Traber MG
Adv Nutr 2014 Sep;5(5):503-14. doi: 10.3945/an.114.006254. PMID: 25469382Free PMC Article
Wiebe VJ, Sipila PE
Crit Rev Oncol Hematol 1994 Apr;16(2):75-112. doi: 10.1016/1040-8428(94)90043-4. PMID: 8068213
Adams PC, Holt DW, Storey GC, Morley AR, Callaghan J, Campbell RW
Circulation 1985 Nov;72(5):1064-75. doi: 10.1161/01.cir.72.5.1064. PMID: 3930086

Prognosis

Lv S, Wang Y, Zhang W, Shang H
Heart 2022 May 25;108(12):917-922. doi: 10.1136/heartjnl-2021-320054. PMID: 34611047
Mohapatra SR, Sadik A, Tykocinski LO, Dietze J, Poschet G, Heiland I, Opitz CA
Front Immunol 2019;10:2762. Epub 2019 Dec 4 doi: 10.3389/fimmu.2019.02762. PMID: 31866995Free PMC Article
Hannan FM, Newey PJ, Whyte MP, Thakker RV
Br J Clin Pharmacol 2019 Jun;85(6):1147-1160. Epub 2018 Nov 28 doi: 10.1111/bcp.13803. PMID: 30357886Free PMC Article
Grover VP, Dresner MA, Forton DM, Counsell S, Larkman DJ, Patel N, Thomas HC, Taylor-Robinson SD
World J Gastroenterol 2006 May 21;12(19):2969-78. doi: 10.3748/wjg.v12.i19.2969. PMID: 16718775Free PMC Article
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400

Clinical prediction guides

Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Olofsson P
Am J Obstet Gynecol 2023 May;228(5S):S1222-S1240. Epub 2023 Mar 19 doi: 10.1016/j.ajog.2022.07.001. PMID: 37164495
Hannan FM, Newey PJ, Whyte MP, Thakker RV
Br J Clin Pharmacol 2019 Jun;85(6):1147-1160. Epub 2018 Nov 28 doi: 10.1111/bcp.13803. PMID: 30357886Free PMC Article
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400
Kumar R
Physiol Rev 1984 Apr;64(2):478-504. doi: 10.1152/physrev.1984.64.2.478. PMID: 6324253

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