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Abnormal circulating protein concentration

MedGen UID:
892289
Concept ID:
C4023679
Finding
Synonyms: Abnormal circulating protein level; Abnormality of circulating protein level; Blood protein disease; Serum protein abnormality
 
HPO: HP:0010876

Definition

An abnormal level of a circulating protein in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating protein concentration

Professional guidelines

PubMed

Berg DD, Ruff CT, Morrow DA
Clin Chem 2021 Jan 8;67(1):87-95. doi: 10.1093/clinchem/hvaa298. PMID: 33313695
Ball SG, Iqbal Z
Best Pract Res Clin Endocrinol Metab 2016 Mar;30(2):161-73. Epub 2015 Dec 30 doi: 10.1016/j.beem.2015.12.001. PMID: 27156756
Castaman G, Goodeve A, Eikenboom J; European Group on von Willebrand Disease
Haematologica 2013 May;98(5):667-74. doi: 10.3324/haematol.2012.077263. PMID: 23633542Free PMC Article

Recent clinical studies

Etiology

Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Castaman G
Thromb Res 2020 Dec;196:618-625. Epub 2020 Aug 3 doi: 10.1016/j.thromres.2020.07.051. PMID: 32819724
Di Ciaula A, Garruti G, Wang DQ, Portincasa P
Eur J Intern Med 2018 Jul;53:3-11. Epub 2018 Apr 26 doi: 10.1016/j.ejim.2018.04.019. PMID: 29706426Free PMC Article
Ball SG, Iqbal Z
Best Pract Res Clin Endocrinol Metab 2016 Mar;30(2):161-73. Epub 2015 Dec 30 doi: 10.1016/j.beem.2015.12.001. PMID: 27156756
Shilova N, Huflejt ME, Vuskovic M, Obukhova P, Navakouski M, Khasbiullina N, Pazynina G, Galanina O, Bazhenov A, Bovin N
Top Curr Chem 2015;366:169-81. doi: 10.1007/128_2013_469. PMID: 24037491

Diagnosis

Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Guindi M
Semin Diagn Pathol 2019 Nov;36(6):415-422. Epub 2019 Jul 25 doi: 10.1053/j.semdp.2019.07.008. PMID: 31421978
Mendoza A, Hollenberg AN
Pharmacol Ther 2017 May;173:135-145. Epub 2017 Feb 4 doi: 10.1016/j.pharmthera.2017.02.012. PMID: 28174093Free PMC Article
Aryasomayajula B, Salzano G, Torchilin VP
Methods Mol Biol 2017;1530:41-61. doi: 10.1007/978-1-4939-6646-2_3. PMID: 28150195
Blevins LS Jr, Wand GS
Crit Care Med 1992 Jan;20(1):69-79. doi: 10.1097/00003246-199201000-00019. PMID: 1729049

Therapy

Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Caron P, Grunenwald S, Persani L, Borson-Chazot F, Leroy R, Duntas L
Rev Endocr Metab Disord 2022 Jun;23(3):463-483. Epub 2021 Oct 20 doi: 10.1007/s11154-021-09691-9. PMID: 34671932Free PMC Article
Ulven SM, Holven KB, Gil A, Rangel-Huerta OD
Adv Nutr 2019 May 1;10(suppl_2):S239-S250. doi: 10.1093/advances/nmy072. PMID: 31089732Free PMC Article
Aryasomayajula B, Salzano G, Torchilin VP
Methods Mol Biol 2017;1530:41-61. doi: 10.1007/978-1-4939-6646-2_3. PMID: 28150195
Klahr S
Intern Med 2000 May;39(5):355-61. doi: 10.2169/internalmedicine.39.355. PMID: 10830173

Prognosis

Donovan K, Herrington WG, Paré G, Pigeyre M, Haynes R, Sardell R, Butterworth AS, Folkersen L, Gustafsson S, Wang Q, Baigent C, Mälarstig A, Holmes MV, Staplin N; on behalf of the SCALLOP Consortium
Clin J Am Soc Nephrol 2023 Jan 1;18(1):17-27. doi: 10.2215/CJN.05080422. PMID: 36719157Free PMC Article
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Strazzella A, Ossoli A, Calabresi L
Cells 2021 Mar 31;10(4) doi: 10.3390/cells10040764. PMID: 33807271Free PMC Article
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, Badesch DB, McGoon MD, McLaughlin VV, Roecker EB, Gerber MJ, Dufton C, Wiens BL, Rubin LJ; Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
Circulation 2008 Jun 10;117(23):3010-9. Epub 2008 May 27 doi: 10.1161/CIRCULATIONAHA.107.742510. PMID: 18506008

Clinical prediction guides

Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Amaya-Garrido A, Brunet M, Buffin-Meyer B, Piedrafita A, Grzesiak L, Agbegbo E, Del Bello A, Ferrandiz I, Ardeleanu S, Bermudez-Lopez M, Fedou C, Camus M, Burlet-Schiltz O, Massines J, Buléon M, Feuillet G, Alves M, Neau E, Casemayou A, Breuil B, Saulnier-Blache JS, Denis C, Voelkl J, Glorieux G, Hobson S, Arefin S, Rahman A, Kublickiene K, Stenvinkel P, Bascands JL, Faguer S, Valdivielso JM, Schanstra JP, Klein J
Sci Transl Med 2023 Sep 6;15(712):eabn5939. doi: 10.1126/scitranslmed.abn5939. PMID: 37672568
Liu Q, Wu J, Zhang X, Li X, Wu X, Zhao Y, Ren J
Cell Death Dis 2021 Jul 3;12(7):673. doi: 10.1038/s41419-021-03961-9. PMID: 34218252Free PMC Article
Strazzella A, Ossoli A, Calabresi L
Cells 2021 Mar 31;10(4) doi: 10.3390/cells10040764. PMID: 33807271Free PMC Article
Shilova N, Huflejt ME, Vuskovic M, Obukhova P, Navakouski M, Khasbiullina N, Pazynina G, Galanina O, Bazhenov A, Bovin N
Top Curr Chem 2015;366:169-81. doi: 10.1007/128_2013_469. PMID: 24037491

Recent systematic reviews

Soltani Khaboushan A, Moeinafshar A, Ersi MH, Teixeira AL, Majidi Zolbin M, Kajbafzadeh AM
J Neuroimmunol 2023 Dec 15;385:578243. Epub 2023 Nov 13 doi: 10.1016/j.jneuroim.2023.578243. PMID: 37984118
Adams C, Conigrave JH, Lewohl J, Haber P, Morley KC
Brain Behav Immun 2020 Oct;89:501-512. Epub 2020 Aug 14 doi: 10.1016/j.bbi.2020.08.002. PMID: 32805393
Ulven SM, Holven KB, Gil A, Rangel-Huerta OD
Adv Nutr 2019 May 1;10(suppl_2):S239-S250. doi: 10.1093/advances/nmy072. PMID: 31089732Free PMC Article
Iljazi A, Ayata C, Ashina M, Hougaard A
Curr Pain Headache Rep 2018 Mar 19;22(4):27. doi: 10.1007/s11916-018-0682-8. PMID: 29557064
Blundell S, Ray KK, Buckland M, White PD
Brain Behav Immun 2015 Nov;50:186-195. Epub 2015 Jul 3 doi: 10.1016/j.bbi.2015.07.004. PMID: 26148446

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