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Malignant glioma

MedGen UID:
107826
Concept ID:
C0555198
Neoplastic Process
Synonyms: Glioma, Malignant; Gliomas, Malignant; Malignant Glioma; Malignant Gliomas
SNOMED CT: Glioma, malignant (74532006); Malignant glioma (74532006)
 
Monarch Initiative: MONDO:0100342

Definition

A grade 3 or grade 4 glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Malignant glioma

Professional guidelines

PubMed

Ghiaseddin AP, Shin D, Melnick K, Tran DD
Curr Treat Options Oncol 2020 Jul 30;21(9):76. doi: 10.1007/s11864-020-00773-5. PMID: 32734509Free PMC Article
Nayak L, DeAngelis LM, Brandes AA, Peereboom DM, Galanis E, Lin NU, Soffietti R, Macdonald DR, Chamberlain M, Perry J, Jaeckle K, Mehta M, Stupp R, Muzikansky A, Pentsova E, Cloughesy T, Iwamoto FM, Tonn JC, Vogelbaum MA, Wen PY, van den Bent MJ, Reardon DA
Neuro Oncol 2017 May 1;19(5):625-635. doi: 10.1093/neuonc/nox029. PMID: 28453751Free PMC Article
Niyazi M, Brada M, Chalmers AJ, Combs SE, Erridge SC, Fiorentino A, Grosu AL, Lagerwaard FJ, Minniti G, Mirimanoff RO, Ricardi U, Short SC, Weber DC, Belka C
Radiother Oncol 2016 Jan;118(1):35-42. Epub 2016 Jan 6 doi: 10.1016/j.radonc.2015.12.003. PMID: 26777122

Recent clinical studies

Etiology

Cahill D, Turcan S
Semin Neurol 2018 Feb;38(1):5-10. Epub 2018 Mar 16 doi: 10.1055/s-0037-1620238. PMID: 29548046
Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, Prabhu SS, Rao G, Fuller GN, Aldape KD, Gumin J, Vence LM, Wistuba I, Rodriguez-Canales J, Villalobos PA, Dirven CMF, Tejada S, Valle RD, Alonso MM, Ewald B, Peterkin JJ, Tufaro F, Fueyo J
J Clin Oncol 2018 May 10;36(14):1419-1427. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.8219. PMID: 29432077Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Liu C, Zong H
Curr Opin Neurobiol 2012 Oct;22(5):844-9. Epub 2012 May 5 doi: 10.1016/j.conb.2012.04.012. PMID: 22560511Free PMC Article
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ; ALA-Glioma Study Group
Lancet Oncol 2006 May;7(5):392-401. doi: 10.1016/S1470-2045(06)70665-9. PMID: 16648043

Diagnosis

Wang LM, Englander ZK, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:1-30. doi: 10.1007/978-3-031-23705-8_1. PMID: 37452933
Norouzi M
Pharmacol Res 2020 Jun;156:104753. Epub 2020 Mar 21 doi: 10.1016/j.phrs.2020.104753. PMID: 32209363
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ; ALA-Glioma Study Group
Lancet Oncol 2006 May;7(5):392-401. doi: 10.1016/S1470-2045(06)70665-9. PMID: 16648043

Therapy

Fares J, Ahmed AU, Ulasov IV, Sonabend AM, Miska J, Lee-Chang C, Balyasnikova IV, Chandler JP, Portnow J, Tate MC, Kumthekar P, Lukas RV, Grimm SA, Adams AK, Hébert CD, Strong TV, Amidei C, Arrieta VA, Zannikou M, Horbinski C, Zhang H, Burdett KB, Curiel DT, Sachdev S, Aboody KS, Stupp R, Lesniak MS
Lancet Oncol 2021 Aug;22(8):1103-1114. Epub 2021 Jun 29 doi: 10.1016/S1470-2045(21)00245-X. PMID: 34214495Free PMC Article
Ghiaseddin AP, Shin D, Melnick K, Tran DD
Curr Treat Options Oncol 2020 Jul 30;21(9):76. doi: 10.1007/s11864-020-00773-5. PMID: 32734509Free PMC Article
Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, Prabhu SS, Rao G, Fuller GN, Aldape KD, Gumin J, Vence LM, Wistuba I, Rodriguez-Canales J, Villalobos PA, Dirven CMF, Tejada S, Valle RD, Alonso MM, Ewald B, Peterkin JJ, Tufaro F, Fueyo J
J Clin Oncol 2018 May 10;36(14):1419-1427. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.8219. PMID: 29432077Free PMC Article
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ; ALA-Glioma Study Group
Lancet Oncol 2006 May;7(5):392-401. doi: 10.1016/S1470-2045(06)70665-9. PMID: 16648043

Prognosis

Wang LM, Englander ZK, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:1-30. doi: 10.1007/978-3-031-23705-8_1. PMID: 37452933
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, Prabhu SS, Rao G, Fuller GN, Aldape KD, Gumin J, Vence LM, Wistuba I, Rodriguez-Canales J, Villalobos PA, Dirven CMF, Tejada S, Valle RD, Alonso MM, Ewald B, Peterkin JJ, Tufaro F, Fueyo J
J Clin Oncol 2018 May 10;36(14):1419-1427. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.8219. PMID: 29432077Free PMC Article
Lan YL, Wang X, Xing JS, Lou JC, Ma XC, Zhang B
Acta Neurol Belg 2017 Sep;117(3):613-621. Epub 2016 Dec 20 doi: 10.1007/s13760-016-0730-2. PMID: 27995487
Reyes-Botero G, Mokhtari K, Martin-Duverneuil N, Delattre JY, Laigle-Donadey F
Oncologist 2012;17(3):388-97. Epub 2012 Mar 1 doi: 10.1634/theoncologist.2011-0335. PMID: 22382458Free PMC Article

Clinical prediction guides

Norouzi M
Pharmacol Res 2020 Jun;156:104753. Epub 2020 Mar 21 doi: 10.1016/j.phrs.2020.104753. PMID: 32209363
Matteoni S, Abbruzzese C, Villani V, Malorni W, Pace A, Matarrese P, Paggi MG
Cancer Lett 2020 Jan 1;468:41-47. Epub 2019 Oct 9 doi: 10.1016/j.canlet.2019.10.012. PMID: 31605777
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Nayak L, DeAngelis LM, Brandes AA, Peereboom DM, Galanis E, Lin NU, Soffietti R, Macdonald DR, Chamberlain M, Perry J, Jaeckle K, Mehta M, Stupp R, Muzikansky A, Pentsova E, Cloughesy T, Iwamoto FM, Tonn JC, Vogelbaum MA, Wen PY, van den Bent MJ, Reardon DA
Neuro Oncol 2017 May 1;19(5):625-635. doi: 10.1093/neuonc/nox029. PMID: 28453751Free PMC Article
Bodera P
Recent Pat Inflamm Allergy Drug Discov 2011 Jan;5(1):87-93. doi: 10.2174/187221311794474856. PMID: 21158735

Recent systematic reviews

Guo B, Zhang S, Xu L, Sun J, Chan WL, Zheng P, Zhang J, Zhang L
Front Immunol 2023;14:966696. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.966696. PMID: 37483593Free PMC Article
D'Alessandris QG, Battistelli M, Pennisi G, Offi M, Martini M, Cenci T, Falchetti ML, Lauretti L, Olivi A, Pallini R, Montano N
Expert Rev Mol Med 2023 Mar 15;25:e10. doi: 10.1017/erm.2023.6. PMID: 36919343
Winter SF, Loebel F, Dietrich J
Crit Rev Oncol Hematol 2017 Apr;112:41-58. Epub 2017 Feb 20 doi: 10.1016/j.critrevonc.2017.02.016. PMID: 28325264
Wang W, Shi G, Ma B, Hao X, Dong X, Zhang B
Turk Neurosurg 2017;27(2):174-181. doi: 10.5137/1019-5149.JTN.15462-15.0. PMID: 27337236
Diamond EL, Corner GW, De Rosa A, Breitbart W, Applebaum AJ
J Neurooncol 2014 Sep;119(2):227-34. Epub 2014 May 30 doi: 10.1007/s11060-014-1487-1. PMID: 24874468Free PMC Article

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