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Grade III glioma

MedGen UID:
925529
•Concept ID:
C4287997
•
Neoplastic Process
Synonyms: Anaplastic Glioma; anaplastic glioma; grade III glioma; WHO Grade 3 Glioma; WHO Grade III Glioma; WHO grade III glioma
 
Monarch Initiative: MONDO:0021640

Definition

A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade III glioma

Professional guidelines

PubMed

Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV).
Wang HC, Lin YT, Lin WC, Ho RW, Lin YJ, Tsai NW, Ho JT, Lu CH
World Neurosurg 2018 Jun;114:e766-e774. Epub 2018 Mar 16 doi: 10.1016/j.wneu.2018.03.078. PMID: 29555610
Input of molecular analysis in medical management of primary brain tumor patients.
Idbaih A, Duran-Peña A, Bonnet C, Ducray F
Rev Neurol (Paris) 2015 Jun-Jul;171(6-7):457-65. Epub 2015 May 27 doi: 10.1016/j.neurol.2015.04.002. PMID: 26026669
Single-agent bevacizumab is an effective treatment in recurrent glioblastoma.
Hacibekiroglu I, Kodaz H, Erdogan B, Turkmen E, Ozcelik M, Esenkaya A, Saygi HM, Uzunoglu S, Cicin I
Med Oncol 2015 Feb;32(2):460. Epub 2015 Jan 9 doi: 10.1007/s12032-014-0460-3. PMID: 25572814

Recent clinical studies

Etiology

Glioma-grade diagnosis using in-phase and out-of-phase T1-weighted magnetic resonance imaging: A prospective study.
De Pardieu M, Boucebci S, Herpe G, Fauche C, Velasco S, Ingrand P, Tasu JP
Diagn Interv Imaging 2020 Jul-Aug;101(7-8):451-456. Epub 2020 May 20 doi: 10.1016/j.diii.2020.04.013. PMID: 32446598
Use of metformin and survival of patients with high-grade glioma.
Seliger C, Luber C, Gerken M, Schaertl J, Proescholdt M, Riemenschneider MJ, Meier CR, Bogdahn U, Leitzmann MF, Klinkhammer-Schalke M, Hau P
Int J Cancer 2019 Jan 15;144(2):273-280. Epub 2018 Oct 26 doi: 10.1002/ijc.31783. PMID: 30091464
Use of statins or NSAIDs and survival of patients with high-grade glioma.
Seliger C, Schaertl J, Gerken M, Luber C, Proescholdt M, Riemenschneider MJ, Leitzmann MF, Hau P, Klinkhammer-Schalke M
PLoS One 2018;13(12):e0207858. Epub 2018 Dec 3 doi: 10.1371/journal.pone.0207858. PMID: 30507932Free PMC Article
Input of molecular analysis in medical management of primary brain tumor patients.
Idbaih A, Duran-Peña A, Bonnet C, Ducray F
Rev Neurol (Paris) 2015 Jun-Jul;171(6-7):457-65. Epub 2015 May 27 doi: 10.1016/j.neurol.2015.04.002. PMID: 26026669
Chemotherapy in glioma.
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article

Diagnosis

Glioma-grade diagnosis using in-phase and out-of-phase T1-weighted magnetic resonance imaging: A prospective study.
De Pardieu M, Boucebci S, Herpe G, Fauche C, Velasco S, Ingrand P, Tasu JP
Diagn Interv Imaging 2020 Jul-Aug;101(7-8):451-456. Epub 2020 May 20 doi: 10.1016/j.diii.2020.04.013. PMID: 32446598
Use of metformin and survival of patients with high-grade glioma.
Seliger C, Luber C, Gerken M, Schaertl J, Proescholdt M, Riemenschneider MJ, Meier CR, Bogdahn U, Leitzmann MF, Klinkhammer-Schalke M, Hau P
Int J Cancer 2019 Jan 15;144(2):273-280. Epub 2018 Oct 26 doi: 10.1002/ijc.31783. PMID: 30091464
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.
Toft A, Urup T, Christensen IJ, Michaelsen SR, Lukram B, Grunnet K, Kosteljanetz M, Larsen VA, Lassen U, Broholm H, Poulsen HS
Cancer Invest 2018 Feb 7;36(2):165-174. Epub 2018 Feb 2 doi: 10.1080/07357907.2018.1430818. PMID: 29393706
Anaplastic astrocytoma.
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article
Chemotherapy in glioma.
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article

Therapy

Use of metformin and survival of patients with high-grade glioma.
Seliger C, Luber C, Gerken M, Schaertl J, Proescholdt M, Riemenschneider MJ, Meier CR, Bogdahn U, Leitzmann MF, Klinkhammer-Schalke M, Hau P
Int J Cancer 2019 Jan 15;144(2):273-280. Epub 2018 Oct 26 doi: 10.1002/ijc.31783. PMID: 30091464
Use of statins or NSAIDs and survival of patients with high-grade glioma.
Seliger C, Schaertl J, Gerken M, Luber C, Proescholdt M, Riemenschneider MJ, Leitzmann MF, Hau P, Klinkhammer-Schalke M
PLoS One 2018;13(12):e0207858. Epub 2018 Dec 3 doi: 10.1371/journal.pone.0207858. PMID: 30507932Free PMC Article
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.
Toft A, Urup T, Christensen IJ, Michaelsen SR, Lukram B, Grunnet K, Kosteljanetz M, Larsen VA, Lassen U, Broholm H, Poulsen HS
Cancer Invest 2018 Feb 7;36(2):165-174. Epub 2018 Feb 2 doi: 10.1080/07357907.2018.1430818. PMID: 29393706
Anaplastic astrocytoma.
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article
Chemotherapy in glioma.
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article

Prognosis

Glycation Leads to Increased Invasion of Glioblastoma Cells.
Schildhauer P, Selke P, Scheller C, Strauss C, Horstkorte R, Leisz S, Scheer M
Cells 2023 Apr 23;12(9) doi: 10.3390/cells12091219. PMID: 37174618Free PMC Article
Use of metformin and survival of patients with high-grade glioma.
Seliger C, Luber C, Gerken M, Schaertl J, Proescholdt M, Riemenschneider MJ, Meier CR, Bogdahn U, Leitzmann MF, Klinkhammer-Schalke M, Hau P
Int J Cancer 2019 Jan 15;144(2):273-280. Epub 2018 Oct 26 doi: 10.1002/ijc.31783. PMID: 30091464
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.
Toft A, Urup T, Christensen IJ, Michaelsen SR, Lukram B, Grunnet K, Kosteljanetz M, Larsen VA, Lassen U, Broholm H, Poulsen HS
Cancer Invest 2018 Feb 7;36(2):165-174. Epub 2018 Feb 2 doi: 10.1080/07357907.2018.1430818. PMID: 29393706
Integrated mRNAseq and microRNAseq data analysis for grade III gliomas.
Dai J, Bing Z, Zhang Y, Li Q, Niu L, Liang W, Yuan G, Duan L, Yin H, Pan Y
Mol Med Rep 2017 Nov;16(5):7468-7478. Epub 2017 Sep 20 doi: 10.3892/mmr.2017.7545. PMID: 28944855Free PMC Article
Anaplastic astrocytoma.
Grimm SA, Chamberlain MC
CNS Oncol 2016 Jul;5(3):145-57. Epub 2016 May 27 doi: 10.2217/cns-2016-0002. PMID: 27230974Free PMC Article

Clinical prediction guides

Survival analysis in high-grade glioma: The role of salvage surgery.
Vargas López AJ, Fernández Carballal C, Valera Melé M, Rodríguez-Boto G
Neurologia (Engl Ed) 2023 Jan-Feb;38(1):21-28. Epub 2022 Dec 1 doi: 10.1016/j.nrleng.2020.04.032. PMID: 36464224
Glioma-grade diagnosis using in-phase and out-of-phase T1-weighted magnetic resonance imaging: A prospective study.
De Pardieu M, Boucebci S, Herpe G, Fauche C, Velasco S, Ingrand P, Tasu JP
Diagn Interv Imaging 2020 Jul-Aug;101(7-8):451-456. Epub 2020 May 20 doi: 10.1016/j.diii.2020.04.013. PMID: 32446598
Use of statins or NSAIDs and survival of patients with high-grade glioma.
Seliger C, Schaertl J, Gerken M, Luber C, Proescholdt M, Riemenschneider MJ, Leitzmann MF, Hau P, Klinkhammer-Schalke M
PLoS One 2018;13(12):e0207858. Epub 2018 Dec 3 doi: 10.1371/journal.pone.0207858. PMID: 30507932Free PMC Article
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.
Toft A, Urup T, Christensen IJ, Michaelsen SR, Lukram B, Grunnet K, Kosteljanetz M, Larsen VA, Lassen U, Broholm H, Poulsen HS
Cancer Invest 2018 Feb 7;36(2):165-174. Epub 2018 Feb 2 doi: 10.1080/07357907.2018.1430818. PMID: 29393706
Input of molecular analysis in medical management of primary brain tumor patients.
Idbaih A, Duran-Peña A, Bonnet C, Ducray F
Rev Neurol (Paris) 2015 Jun-Jul;171(6-7):457-65. Epub 2015 May 27 doi: 10.1016/j.neurol.2015.04.002. PMID: 26026669

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