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Locally Advanced Glioma

MedGen UID:
1793124
•Concept ID:
C5556683
•
Neoplastic Process

Definition

Glioma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

The evolving role of reirradiation in the management of recurrent brain tumors.
De Pietro R, Zaccaro L, Marampon F, Tini P, De Felice F, Minniti G
J Neurooncol 2023 Sep;164(2):271-286. Epub 2023 Aug 25 doi: 10.1007/s11060-023-04407-2. PMID: 37624529Free PMC Article
Treatment of Glioblastoma.
Nam JY, de Groot JF
J Oncol Pract 2017 Oct;13(10):629-638. doi: 10.1200/JOP.2017.025536. PMID: 29020535
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article

Recent clinical studies

Etiology

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Current status and recent advances in reirradiation of glioblastoma.
Minniti G, Niyazi M, Alongi F, Navarria P, Belka C
Radiat Oncol 2021 Feb 18;16(1):36. doi: 10.1186/s13014-021-01767-9. PMID: 33602305Free PMC Article
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau DY, Morris PJ, Zhao JJ, Thomas CJ, Monje M
Nature 2017 Sep 28;549(7673):533-537. Epub 2017 Sep 20 doi: 10.1038/nature24014. PMID: 28959975Free PMC Article
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article

Diagnosis

Integrated proteogenomic characterization of glioblastoma evolution.
Kim KH, Migliozzi S, Koo H, Hong JH, Park SM, Kim S, Kwon HJ, Ha S, Garofano L, Oh YT, D'Angelo F, Kim CI, Kim S, Lee JY, Kim J, Hong J, Jang EH, Mathon B, Di Stefano AL, Bielle F, Laurenge A, Nesvizhskii AI, Hur EM, Yin J, Shi B, Kim Y, Moon KS, Kwon JT, Lee SH, Lee SH, Gwak HS, Lasorella A, Yoo H, Sanson M, Sa JK, Park CK, Nam DH, Iavarone A, Park JB
Cancer Cell 2024 Mar 11;42(3):358-377.e8. Epub 2024 Jan 11 doi: 10.1016/j.ccell.2023.12.015. PMID: 38215747Free PMC Article
Glioblastoma heterogeneity at single cell resolution.
Eisenbarth D, Wang YA
Oncogene 2023 Jun;42(27):2155-2165. Epub 2023 Jun 5 doi: 10.1038/s41388-023-02738-y. PMID: 37277603Free PMC Article
EANM procedure guidelines for brain PET imaging using [(18)F]FDG, version 3.
Guedj E, Varrone A, Boellaard R, Albert NL, Barthel H, van Berckel B, Brendel M, Cecchin D, Ekmekcioglu O, Garibotto V, Lammertsma AA, Law I, Peñuelas I, Semah F, Traub-Weidinger T, van de Giessen E, Van Weehaeghe D, Morbelli S
Eur J Nucl Med Mol Imaging 2022 Jan;49(2):632-651. Epub 2021 Dec 9 doi: 10.1007/s00259-021-05603-w. PMID: 34882261Free PMC Article
Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma.
DeCordova S, Shastri A, Tsolaki AG, Yasmin H, Klein L, Singh SK, Kishore U
Front Immunol 2020;11:1402. Epub 2020 Jul 17 doi: 10.3389/fimmu.2020.01402. PMID: 32765498Free PMC Article
Glioblastoma: Overview of Disease and Treatment.
Davis ME
Clin J Oncol Nurs 2016 Oct 1;20(5 Suppl):S2-8. doi: 10.1188/16.CJON.S1.2-8. PMID: 27668386Free PMC Article

Therapy

Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.
Todo T, Ito H, Ino Y, Ohtsu H, Ota Y, Shibahara J, Tanaka M
Nat Med 2022 Aug;28(8):1630-1639. Epub 2022 Jul 21 doi: 10.1038/s41591-022-01897-x. PMID: 35864254Free PMC Article
Current status and recent advances in reirradiation of glioblastoma.
Minniti G, Niyazi M, Alongi F, Navarria P, Belka C
Radiat Oncol 2021 Feb 18;16(1):36. doi: 10.1186/s13014-021-01767-9. PMID: 33602305Free PMC Article
Nanocarrier-based drug combination therapy for glioblastoma.
Zhao M, van Straten D, Broekman MLD, Préat V, Schiffelers RM
Theranostics 2020;10(3):1355-1372. Epub 2020 Jan 1 doi: 10.7150/thno.38147. PMID: 31938069Free PMC Article
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Current state of immunotherapy for glioblastoma.
Lim M, Xia Y, Bettegowda C, Weller M
Nat Rev Clin Oncol 2018 Jul;15(7):422-442. doi: 10.1038/s41571-018-0003-5. PMID: 29643471

Prognosis

Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization.
Wang W, Li T, Cheng Y, Li F, Qi S, Mao M, Wu J, Liu Q, Zhang X, Li X, Zhang L, Qi H, Yang L, Yang K, He Z, Ding S, Qin Z, Yang Y, Yang X, Luo C, Guo Y, Wang C, Liu X, Zhou L, Liu Y, Kong W, Miao J, Ye S, Luo M, An L, Wang L, Che L, Niu Q, Ma Q, Zhang X, Zhang Z, Hu R, Feng H, Ping YF, Bian XW, Shi Y
Cancer Cell 2024 May 13;42(5):815-832.e12. Epub 2024 Apr 18 doi: 10.1016/j.ccell.2024.03.013. PMID: 38640932
Emerging therapies for glioblastoma: current state and future directions.
Rong L, Li N, Zhang Z
J Exp Clin Cancer Res 2022 Apr 15;41(1):142. doi: 10.1186/s13046-022-02349-7. PMID: 35428347Free PMC Article
Current status and recent advances in reirradiation of glioblastoma.
Minniti G, Niyazi M, Alongi F, Navarria P, Belka C
Radiat Oncol 2021 Feb 18;16(1):36. doi: 10.1186/s13014-021-01767-9. PMID: 33602305Free PMC Article
A review of glioblastoma immunotherapy.
Medikonda R, Dunn G, Rahman M, Fecci P, Lim M
J Neurooncol 2021 Jan;151(1):41-53. Epub 2020 Apr 6 doi: 10.1007/s11060-020-03448-1. PMID: 32253714
Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma.
DeCordova S, Shastri A, Tsolaki AG, Yasmin H, Klein L, Singh SK, Kishore U
Front Immunol 2020;11:1402. Epub 2020 Jul 17 doi: 10.3389/fimmu.2020.01402. PMID: 32765498Free PMC Article

Clinical prediction guides

Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization.
Wang W, Li T, Cheng Y, Li F, Qi S, Mao M, Wu J, Liu Q, Zhang X, Li X, Zhang L, Qi H, Yang L, Yang K, He Z, Ding S, Qin Z, Yang Y, Yang X, Luo C, Guo Y, Wang C, Liu X, Zhou L, Liu Y, Kong W, Miao J, Ye S, Luo M, An L, Wang L, Che L, Niu Q, Ma Q, Zhang X, Zhang Z, Hu R, Feng H, Ping YF, Bian XW, Shi Y
Cancer Cell 2024 May 13;42(5):815-832.e12. Epub 2024 Apr 18 doi: 10.1016/j.ccell.2024.03.013. PMID: 38640932
Border-associated macrophages in the central nervous system.
Sun R, Jiang H
J Neuroinflammation 2024 Mar 13;21(1):67. doi: 10.1186/s12974-024-03059-x. PMID: 38481312Free PMC Article
Identifying predictors of glioma evolution from longitudinal sequencing.
Mu Q, Chai R, Pang B, Yang Y, Liu H, Zhao Z, Bao Z, Song D, Zhu Z, Yan M, Jiang B, Mo Z, Tang J, Sa JK, Cho HJ, Chang Y, Chan KHY, Loi DSC, Tam SST, Chan AKY, Wu AR, Liu Z, Poon WS, Ng HK, Chan DTM, Iavarone A, Nam DH, Jiang T, Wang J
Sci Transl Med 2023 Oct 4;15(716):eadh4181. doi: 10.1126/scitranslmed.adh4181. PMID: 37792958
Imaging of oligodendroglioma.
Smits M
Br J Radiol 2016;89(1060):20150857. Epub 2016 Feb 5 doi: 10.1259/bjr.20150857. PMID: 26849038Free PMC Article
Vismodegib.
Rudin CM
Clin Cancer Res 2012 Jun 15;18(12):3218-22. Epub 2012 Jun 7 doi: 10.1158/1078-0432.CCR-12-0568. PMID: 22679179Free PMC Article

Recent systematic reviews

Efficacy and Safety of Intraoperative Radiotherapy for High-Grade Gliomas: A Systematic Review and Meta-Analysis.
Palavani LB, de Barros Oliveira L, Reis PA, Batista S, Santana LS, de Freitas Martins LP, Rabelo NN, Bertani R, Welling LC, Figueiredo EG, Paiva WS, Neville IS
Neurosurg Rev 2024 Jan 15;47(1):47. doi: 10.1007/s10143-024-02279-2. PMID: 38221545
Glioblastoma Immunotherapy: A Systematic Review of the Present Strategies and Prospects for Advancements.
Agosti E, Zeppieri M, De Maria L, Tedeschi C, Fontanella MM, Panciani PP, Ius T
Int J Mol Sci 2023 Oct 10;24(20) doi: 10.3390/ijms242015037. PMID: 37894718Free PMC Article
Physical Forces in Glioblastoma Migration: A Systematic Review.
Grossen A, Smith K, Coulibaly N, Arbuckle B, Evans A, Wilhelm S, Jones K, Dunn I, Towner R, Wu D, Kim YT, Battiste J
Int J Mol Sci 2022 Apr 6;23(7) doi: 10.3390/ijms23074055. PMID: 35409420Free PMC Article
Does local drug delivery still hold therapeutic promise for brain cancer? A systematic review.
Bastiancich C, Bozzato E, Henley I, Newland B
J Control Release 2021 Sep 10;337:296-305. Epub 2021 Jul 21 doi: 10.1016/j.jconrel.2021.07.031. PMID: 34298055
Systematic assessment of clinical outcomes and toxicities of proton radiotherapy for reirradiation.
Verma V, Rwigema JM, Malyapa RS, Regine WF, Simone CB 2nd
Radiother Oncol 2017 Oct;125(1):21-30. Epub 2017 Sep 20 doi: 10.1016/j.radonc.2017.08.005. PMID: 28941560

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