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Recurrent Diffuse Intrinsic Pontine Glioma

MedGen UID:
1624822
•Concept ID:
C4526752
•
Neoplastic Process

Definition

The reemergence of diffuse intrinsic pontine glioma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Diffuse Intrinsic Pontine Glioma

Professional guidelines

PubMed

Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S
J Neurooncol 2018 Dec;140(3):629-638. Epub 2018 Sep 11 doi: 10.1007/s11060-018-2991-5. PMID: 30206764
Treatment of recurrent diffuse intrinsic pontine glioma: the MD Anderson Cancer Center experience.
Wolff JE, Rytting ME, Vats TS, Zage PE, Ater JL, Woo S, Kuttesch J, Ketonen L, Mahajan A
J Neurooncol 2012 Jan;106(2):391-7. Epub 2011 Aug 20 doi: 10.1007/s11060-011-0677-3. PMID: 21858608Free PMC Article

Recent clinical studies

Etiology

Hypofractionated re-irradiation for diffuse intrinsic pontine glioma.
Mankuzhy NP, Tringale KR, Dunkel IJ, Farouk Sait S, Souweidane MM, Khakoo Y, Karajannis MA, Wolden S
Pediatr Blood Cancer 2024 May;71(5):e30929. Epub 2024 Mar 2 doi: 10.1002/pbc.30929. PMID: 38430472
Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma.
Krishnatry R, Manjali JJ, Chinnaswamy G, Chatterjee A, Goda JS, Janu A, Sahu A, Jalali R, Gupta T
Jpn J Clin Oncol 2021 Apr 30;51(5):762-768. doi: 10.1093/jjco/hyab006. PMID: 33521824
Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.
van der Louw EJTM, Reddingius RE, Olieman JF, Neuteboom RF, Catsman-Berrevoets CE
Pediatr Blood Cancer 2019 Mar;66(3):e27561. Epub 2018 Nov 28 doi: 10.1002/pbc.27561. PMID: 30484948
Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S
J Neurooncol 2018 Dec;140(3):629-638. Epub 2018 Sep 11 doi: 10.1007/s11060-018-2991-5. PMID: 30206764
Treatment of recurrent diffuse intrinsic pontine glioma: the MD Anderson Cancer Center experience.
Wolff JE, Rytting ME, Vats TS, Zage PE, Ater JL, Woo S, Kuttesch J, Ketonen L, Mahajan A
J Neurooncol 2012 Jan;106(2):391-7. Epub 2011 Aug 20 doi: 10.1007/s11060-011-0677-3. PMID: 21858608Free PMC Article

Diagnosis

Hypofractionated re-irradiation for diffuse intrinsic pontine glioma.
Mankuzhy NP, Tringale KR, Dunkel IJ, Farouk Sait S, Souweidane MM, Khakoo Y, Karajannis MA, Wolden S
Pediatr Blood Cancer 2024 May;71(5):e30929. Epub 2024 Mar 2 doi: 10.1002/pbc.30929. PMID: 38430472
Longitudinal Monitoring of Gd-DTPA Following Convection Enhanced Delivery in the Brainstem.
Tosi U, Souweidane MM
World Neurosurg 2020 May;137:38-42. Epub 2020 Feb 3 doi: 10.1016/j.wneu.2020.01.199. PMID: 32028001
Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.
van der Louw EJTM, Reddingius RE, Olieman JF, Neuteboom RF, Catsman-Berrevoets CE
Pediatr Blood Cancer 2019 Mar;66(3):e27561. Epub 2018 Nov 28 doi: 10.1002/pbc.27561. PMID: 30484948
Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S
J Neurooncol 2018 Dec;140(3):629-638. Epub 2018 Sep 11 doi: 10.1007/s11060-018-2991-5. PMID: 30206764
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
Burzynski SR, Janicki TJ, Burzynski GS, Marszalek A
Childs Nerv Syst 2014 Dec;30(12):2051-61. Epub 2014 Apr 10 doi: 10.1007/s00381-014-2401-z. PMID: 24718705Free PMC Article

Therapy

Longitudinal Monitoring of Gd-DTPA Following Convection Enhanced Delivery in the Brainstem.
Tosi U, Souweidane MM
World Neurosurg 2020 May;137:38-42. Epub 2020 Feb 3 doi: 10.1016/j.wneu.2020.01.199. PMID: 32028001
Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.
van der Louw EJTM, Reddingius RE, Olieman JF, Neuteboom RF, Catsman-Berrevoets CE
Pediatr Blood Cancer 2019 Mar;66(3):e27561. Epub 2018 Nov 28 doi: 10.1002/pbc.27561. PMID: 30484948
Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S
J Neurooncol 2018 Dec;140(3):629-638. Epub 2018 Sep 11 doi: 10.1007/s11060-018-2991-5. PMID: 30206764
Main editor's comment to the paper: the response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma. Stanislaw R. Burzynski, Tomasz J. Janicki, Gregory S. Burzynski, Ania Marszalek.
Di Rocco C
Childs Nerv Syst 2014 Dec;30(12):2063. Epub 2014 Aug 6 doi: 10.1007/s00381-014-2513-5. PMID: 25096071
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
Burzynski SR, Janicki TJ, Burzynski GS, Marszalek A
Childs Nerv Syst 2014 Dec;30(12):2051-61. Epub 2014 Apr 10 doi: 10.1007/s00381-014-2401-z. PMID: 24718705Free PMC Article

Prognosis

Hypofractionated re-irradiation for diffuse intrinsic pontine glioma.
Mankuzhy NP, Tringale KR, Dunkel IJ, Farouk Sait S, Souweidane MM, Khakoo Y, Karajannis MA, Wolden S
Pediatr Blood Cancer 2024 May;71(5):e30929. Epub 2024 Mar 2 doi: 10.1002/pbc.30929. PMID: 38430472
Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma.
Krishnatry R, Manjali JJ, Chinnaswamy G, Chatterjee A, Goda JS, Janu A, Sahu A, Jalali R, Gupta T
Jpn J Clin Oncol 2021 Apr 30;51(5):762-768. doi: 10.1093/jjco/hyab006. PMID: 33521824
Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.
van der Louw EJTM, Reddingius RE, Olieman JF, Neuteboom RF, Catsman-Berrevoets CE
Pediatr Blood Cancer 2019 Mar;66(3):e27561. Epub 2018 Nov 28 doi: 10.1002/pbc.27561. PMID: 30484948
Main editor's comment to the paper: the response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma. Stanislaw R. Burzynski, Tomasz J. Janicki, Gregory S. Burzynski, Ania Marszalek.
Di Rocco C
Childs Nerv Syst 2014 Dec;30(12):2063. Epub 2014 Aug 6 doi: 10.1007/s00381-014-2513-5. PMID: 25096071
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
Burzynski SR, Janicki TJ, Burzynski GS, Marszalek A
Childs Nerv Syst 2014 Dec;30(12):2051-61. Epub 2014 Apr 10 doi: 10.1007/s00381-014-2401-z. PMID: 24718705Free PMC Article

Clinical prediction guides

Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma.
Krishnatry R, Manjali JJ, Chinnaswamy G, Chatterjee A, Goda JS, Janu A, Sahu A, Jalali R, Gupta T
Jpn J Clin Oncol 2021 Apr 30;51(5):762-768. doi: 10.1093/jjco/hyab006. PMID: 33521824
Longitudinal Monitoring of Gd-DTPA Following Convection Enhanced Delivery in the Brainstem.
Tosi U, Souweidane MM
World Neurosurg 2020 May;137:38-42. Epub 2020 Feb 3 doi: 10.1016/j.wneu.2020.01.199. PMID: 32028001
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
Burzynski SR, Janicki TJ, Burzynski GS, Marszalek A
Childs Nerv Syst 2014 Dec;30(12):2051-61. Epub 2014 Apr 10 doi: 10.1007/s00381-014-2401-z. PMID: 24718705Free PMC Article

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