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Series GSE77439 Query DataSets for GSE77439
Status Public on Feb 02, 2016
Title Development of gene signatures of human unipotent megakaryocyte progenitor and other hematopoietic stem and progenitor populations
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We newly identified prospectively-isolatable unipotent megakaryocyte progenitor population (MegP) as the major source of megakaryocytes, which emerges directly from early stage of hematopoiesis bypassing megakaryocyte-erythroid lineage bifurcation and contributes to physiological and pathological human megakaryopoiesis. To explore gene expression signature of hematopoietic stem/progenitor populrations miroarry-based whole transcriptome analysis was performed. As a result, gene expression signature of MegP clearly reflected its differentiation potential.
Overall design Gene expression profile of megakaryocyte progenitor and other hematopoietic stem and progenitor populations (Manz et al., PNAS, 2002), which were derived from bone marrow aspirates, were analyzed.
Contributor(s) Miyawaki K
Citation(s) 28336526
Submission date Feb 01, 2016
Last update date Apr 09, 2020
Contact name Kohta Miyawaki
Organization name Kyushu University
Street address 3-1-1, Maidashi, Higashi-ku
City Fukuoka
ZIP/Postal code 812-8582
Country Japan
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (21)
GSM2051845 MEP rep1
GSM2051846 GMP rep1
GSM2051847 CMP rep1
BioProject PRJNA310336

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE77439_RAW.tar 64.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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