Similar studies for GEO DataSets (Select 200185859) - GEO DataSets

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Items: 18

Select item 2001858591.

Screening for potential target genes of hsa-mir-199a-1 and hsa-mir-4423 using Clariom D arrays

(Submitter supplied) We screened for target genes of hsa-mir-199a-1 and hsa-mir-4423 by transcriptome profiling. The miRNAs were overexpressed in HeLa cells by transient transfection of precursor miRNA expression plasmids. High-density Clariom D arrays for human were used for the gene expression analysis. This GEO entry provides the microarray data preprocessed according to the gene level workflow.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL23126
18 Samples

Download data: CEL

Series

Accession:: GSE185859

ID:: 200185859

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001207692.

Screening for potential target genes of microRNA-548ac using HTA 2.0 microarrays

(Submitter supplied) We screened for target genes of hsa-miR-548ac by transcriptome profiling. The miRNA was overexpressed in HeLa cells by transient transfection of a precursor miRNA expression plasmid. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis. This GEO entry provides the microarray data preprocessed according to the gene level workflow.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
10 Samples

Download data: CEL, CHP

Series

Accession:: GSE120769

ID:: 200120769

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Select item 2001908473.

Transcriptome data of B cells from patients with multiple sclerosis and healthy controls

(Submitter supplied) We analyzed the transcriptome profile of B cells from patients with relapsing-remitting multiple sclerosis (RRMS), patients with primary progressive multiple sclerosis (PPMS) and healthy individuals. High-density Clariom D Arrays for human were used to quantify the transcript levels. This GEO entry provides the processed Clariom D microarray data from the gene-level and exon-level workflows.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL23126
121 Samples

Download data: CEL, CHP, TXT

Series

Accession:: GSE190847

ID:: 200190847

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Select item 2001050274.

Circulating microRNA signature as novel biomarkers for osteoarthritis development

(Submitter supplied) Introduction: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients. Methods: Serum samples were collected from 12 primary OA patients and 12 healthy individuals and were screened using the Agilent Human miRNA Microarray. Receiver Operating Characteristic (ROC) curves were constructed to evaluate the diagnostic performance of the deregulated miRNAs. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL21575
24 Samples

Download data: TXT

Series

Accession:: GSE105027

ID:: 200105027

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Select item 2001805135.

Genome-wide small RNA sequencing of proliferative and replicative senescent human vascular smooth muscle cells and exosomes

(Submitter supplied) We report high-throughput sequencing of small RNAs can compare the profiles between proliferative and replicative senescent human vascular smooth muscle cells and exosomes

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL18573
12 Samples

Download data: XLS, XLSX

Series

Accession:: GSE180513

ID:: 200180513

Select item 2000345366.

Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma

(Submitter supplied) MicroRNAs (miRNAs) are a novel class of short RNAs which have shown to be dysregulated in a variety of cancers including squamous cell carcinoma (SCC) of the head&neck. Microarray based miRNA expression profiles of cutaneous SCC (cSCC) however have not been investigated so far. Seven patients with cutaneous SCC were enrolled in the study. Tumor biopsies (n=7) were taken from the center of the tumor. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL15019
14 Samples

Download data: TXT

Series

Accession:: GSE34536

ID:: 200034536

Select item 2000344607.

Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic naevi

(Submitter supplied) Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cutaneous malignant melanoma metastases (CMMM) and benign melanocytic naevi (BMN) is limited. Patients with PCMM (n=9), CMMM (n=4) and BMN (n=8) were included in the study. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL15019
21 Samples

Download data: TXT

Series

Accession:: GSE34460

ID:: 200034460

Select item 2001967978.

microRNA Expression in Normal and Diabetic Pancreatic Islets

(Submitter supplied) Genetic studies have identified ≥240 loci associated with type 2 diabetes (T2D), yet most of these loci lie in non-coding regions, masking the underlying molecular mechanisms. Recent studies investigating gene expression in pancreatic islets have provided key insights into the molecular drivers of T2D pathophysiology through comprehensive genetic and genomic analyses. However, similar studies investigating microRNA (miRNA) expression remain limited. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing

Platforms:: GPL16791 GPL18573
14 Samples

Download data: CSV

Series

Accession:: GSE196797

ID:: 200196797

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Select item 2000489599.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6244
48 Samples

Download data: CEL

Series

Accession:: GSE48959

ID:: 200048959

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Select item 20004895810.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
21 Samples

Download data: CEL

Series

Accession:: GSE48958

ID:: 200048958

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Select item 20004895711.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
27 Samples

Download data: CEL

Series

Accession:: GSE48957

ID:: 200048957

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Select item 20001784612.

miRNA Profiling from total blood of Multiple Sclerosis and control samples

(Submitter supplied) This project aims at the detection of specific patterns of miRNAs in peripheral blood samples of MS patients. As controls, blood of donors without known affection have been tested. Using the miRNA patterns we hope to detect a diagnostic pattern for the non-invasive diagnosis of MS.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL9040
41 Samples

Download data: TXT

Series

Accession:: GSE17846

ID:: 200017846

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Select item 20018001713.

rs41291957 alters secondary RNA structure of the human pri-miR-143/145

(Submitter supplied) Purpose: To evaluate whether the single nucleotide polimorphsim rs41291957, located in the pri-miR-143/145, influences the primary RNA secondary structure. Methods: In vitro transcription and folding for the pri-miR-143/145 carrying the WT allele (G) or the mutated one (A) was carried out. The RNAs were then subjected to RNAseI treatement for 30 minutes and RNA seq performed on the digested nucleic acids. more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL21697
2 Samples

Download data: TXT

Series

Accession:: GSE180017

ID:: 200180017

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20017460814.

Identification of 5'isomiR in HCC patients.

(Submitter supplied) The microRNA (miRNA) processing is a critical step for production of mature miRNAs. Its dysregulation leads to the increase of miRNA isoforms with heterogenous 5’ ends (isomiRs), recognizing distinct target sites with a shifted seed sequence. Although some miRNA genes display productive expression of their 5’-isomiRs in cancers, how the production is controlled and how they impact on tumor progression are unexplored yet. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
75 Samples

Download data: TXT

Series

Accession:: GSE174608

ID:: 200174608

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20011456415.

Identification of novel serum biomarkers in early-stage HCC patients.

(Submitter supplied) Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and is the one of the few cancers in which a continued increase in incidence has been observed over several years. HCC associated with chronic liver disease evolves from precancerous lesion and early HCC to overt cancer, and identifying key molecules contributing to early stage HCC is an urgent need. α-Fetoprotein (AFP) is the best serum biomarker for diagnosis of HCC, but sensitivity is low, particularly in detection of early-stage HCC. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
118 Samples

Download data: TXT

Series

Accession:: GSE114564

ID:: 200114564

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Select item 20022418816.

Effects of miR-4707-3p expression on differentiation of primary human neural progenitor cells

(Submitter supplied) To test the effects of miR-4707-3p expression on gene expression and differentiation of primary human neural progenitor cells (phNPCs), we produced two doxycycline inducible stable cell lines using lentiviral transduction. Lines expressed either mir-4707 and GFP or only GFP using the pTRIPZ expression vector. Stable lines were grown in differentiation media with doxycycline for one or two weeks before RNA was extracted and assayed on a Clariom S Pico Microarray Assay.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL24324
24 Samples

Download data: CEL

Series

Accession:: GSE224188

ID:: 200224188

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Select item 20004298117.

RIP: miR-202 mimic-transfected HeLa cells vs. negative control

(Submitter supplied) Potential miR-202 targets were identified using a targetome-wide RIP-based microarray. HeLa cells were transfected with either a miR-202 mimic or a scrambled single-stranded RNA negative control. RNA was isolated from total cell lysate prior to IP and from antibody-immobilized Protein G agarose beads-RNP complexes (post-IP).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
4 Samples

Download data: TXT

Series

Accession:: GSE42981

ID:: 200042981

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Select item 20022433818.

Ribosomal protein L24 mediates mammalian microRNA processing in an evolutionarily conserved manner

(Submitter supplied) To pursue miR-608’s functional impact and elucidate mechanisms regulating its expression, we created transgenic mice expressing miR-608. We further found that its levels are regulated by RPL24 and performed RPL24 knockdown experiments in HEK293T cells.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
6 Samples

Download data: CSV

Series

Accession:: GSE224338

ID:: 200224338

PubMed Full text in PMC Similar studies

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