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Gastric carcinoma

MedGen UID:
147066
•Concept ID:
C0699791
•
Neoplastic Process
Synonyms: Adult stomach carcinoma; Stomach carcinoma
SNOMED CT: Carcinoma of stomach (372143007); Gastric carcinoma (372143007)
 
Monarch Initiative: MONDO:0004950

Definition

A malignant epithelial tumor of the stomach mucosa. The vast majority of gastric carcinomas are adenocarcinomas, arising from the gastric glandular epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
Follow this link to review classifications for Gastric carcinoma in Orphanet.

Professional guidelines

PubMed

Costs of Cancer Prevention: Physical and Psychosocial Sequelae of Risk-Reducing Total Gastrectomy.
Gallanis AF, Gamble LA, Samaranayake SG, Lopez R, Rhodes A, Rajasimhan S, Fasaye GA, Juma O, Connolly M, Joyce S, Berger A, Heller T, Blakely AM, Hernandez JM, Davis JL
J Clin Oncol 2024 Feb 1;42(4):421-430. Epub 2023 Oct 30 doi: 10.1200/JCO.23.01238. PMID: 37903316Free PMC Article
Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa's cascade underlie its therapeutic effects.
Liu Q, Tang J, Chen S, Hu S, Shen C, Xiang J, Chen N, Wang J, Ma X, Zhang Y, Zeng J
Pharmacol Res 2022 Oct;184:106440. Epub 2022 Sep 13 doi: 10.1016/j.phrs.2022.106440. PMID: 36108874
Japanese classification of gastric carcinoma: 3rd English edition.
Japanese Gastric Cancer Association
Gastric Cancer 2011 Jun;14(2):101-12. doi: 10.1007/s10120-011-0041-5. PMID: 21573743

Recent clinical studies

Etiology

Histomorphological analysis of gastric polyps.
Amarapurkar AD, Kale KM, Naik LP, Shukla AP
Indian J Pathol Microbiol 2021 Jun;64(Supplement):S69-S72. doi: 10.4103/IJPM.IJPM_118_20. PMID: 34135141
Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota.
Ferreira RM, Pereira-Marques J, Pinto-Ribeiro I, Costa JL, Carneiro F, Machado JC, Figueiredo C
Gut 2018 Feb;67(2):226-236. Epub 2017 Nov 4 doi: 10.1136/gutjnl-2017-314205. PMID: 29102920Free PMC Article
Lymphoepithelioma-like gastric carcinoma: clinicopathological characteristics and infection status.
Ramos MFKP, Pereira MA, Dias AR, Faraj SF, Zilberstein B, Cecconello I, de Mello ES, Ribeiro Junior U
J Surg Res 2017 Apr;210:159-168. Epub 2016 Nov 11 doi: 10.1016/j.jss.2016.11.012. PMID: 28457323
Gastric carcinoma in canines and humans, a review.
Hugen S, Thomas RE, German AJ, Burgener IA, Mandigers PJJ
Vet Comp Oncol 2017 Sep;15(3):692-705. Epub 2016 Aug 22 doi: 10.1111/vco.12249. PMID: 27549077
Recent advances in proximal gastric carcinoma.
Huang Q, Sun Q, Fan XS, Zhou D, Zou XP
J Dig Dis 2016 Jul;17(7):421-32. doi: 10.1111/1751-2980.12355. PMID: 27129018

Diagnosis

Cutaneous metastasis from gastric carcinoma.
Zhang LW, Wang WJ, Chen T, Xu RH
Cleve Clin J Med 2023 Sep 1;90(9):533-534. doi: 10.3949/ccjm.90a.22085. PMID: 37657833
Assessment of Epinephrine and Norepinephrine in Gastric Carcinoma.
Mehedințeanu AM, Sfredel V, Stovicek PO, Schenker M, Târtea GC, Istrătoaie O, Ciurea AM, Vere CC
Int J Mol Sci 2021 Feb 18;22(4) doi: 10.3390/ijms22042042. PMID: 33670813Free PMC Article
Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota.
Ferreira RM, Pereira-Marques J, Pinto-Ribeiro I, Costa JL, Carneiro F, Machado JC, Figueiredo C
Gut 2018 Feb;67(2):226-236. Epub 2017 Nov 4 doi: 10.1136/gutjnl-2017-314205. PMID: 29102920Free PMC Article
Gastric carcinoma in canines and humans, a review.
Hugen S, Thomas RE, German AJ, Burgener IA, Mandigers PJJ
Vet Comp Oncol 2017 Sep;15(3):692-705. Epub 2016 Aug 22 doi: 10.1111/vco.12249. PMID: 27549077
Gastric Carcinoma: Recent Trends in Diagnostic Biomarkers and Molecular Targeted Therapies.
Majeed W, Iftikhar A, Khaliq T, Aslam B, Muzaffar H, Atta K, Mahmood A, Waris S
Asian Pac J Cancer Prev 2016;17(7):3053-60. PMID: 27509928

Therapy

Five-Year Survival Outcomes of Laparoscopy-Assisted vs Open Distal Gastrectomy for Advanced Gastric Cancer: The JLSSG0901 Randomized Clinical Trial.
Etoh T, Ohyama T, Sakuramoto S, Tsuji T, Lee SW, Yoshida K, Koeda K, Hiki N, Kunisaki C, Tokunaga M, Otsubo D, Takagane A, Misawa K, Kinoshita T, Cho H, Doki Y, Nunobe S, Shiraishi N, Kitano S; Japanese Laparoscopic Surgery Study Group (JLSSG)
JAMA Surg 2023 May 1;158(5):445-454. doi: 10.1001/jamasurg.2023.0096. PMID: 36920382Free PMC Article
Regional therapy trials in peritoneal metastases: The path to standardization of care: Introduction.
Foster JM, Alexander HR, Zhang C
J Surg Oncol 2022 Jan;125(1):55-56. Epub 2021 Nov 11 doi: 10.1002/jso.26750. PMID: 34762306
Integrated Safety Analysis of Abrocitinib for the Treatment of Moderate-to-Severe Atopic Dermatitis From the Phase II and Phase III Clinical Trial Program.
Simpson EL, Silverberg JI, Nosbaum A, Winthrop KL, Guttman-Yassky E, Hoffmeister KM, Egeberg A, Valdez H, Zhang M, Farooqui SA, Romero W, Thorpe AJ, Rojo R, Johnson S
Am J Clin Dermatol 2021 Sep;22(5):693-707. Epub 2021 Aug 18 doi: 10.1007/s40257-021-00618-3. PMID: 34406619Free PMC Article
Vaccine Development for Epstein-Barr Virus.
Cohen JI
Adv Exp Med Biol 2018;1045:477-493. doi: 10.1007/978-981-10-7230-7_22. PMID: 29896681Free PMC Article
Gastric carcinoma.
Fuchs CS, Mayer RJ
N Engl J Med 1995 Jul 6;333(1):32-41. doi: 10.1056/NEJM199507063330107. PMID: 7776992

Prognosis

Gastric cancer in Jammu and Kashmir, India: A review of genetic perspectives.
Shah R, Khaitan PG, Pandita TK, Rafiq A, Abrol D, Suri J, Kaul S, Kumar R, Sharma S
J Cancer Res Ther 2022 Jul-Sep;18(4):873-879. doi: 10.4103/jcrt.JCRT_12_19. PMID: 33533734
Recent advances in proximal gastric carcinoma.
Huang Q, Sun Q, Fan XS, Zhou D, Zou XP
J Dig Dis 2016 Jul;17(7):421-32. doi: 10.1111/1751-2980.12355. PMID: 27129018
Risk Factors and Epidemiology of Gastric Cancer in Pakistan.
Daniyal M, Ahmad S, Ahmad M, Asif HM, Akram M, Ur Rehman S, Sultana S
Asian Pac J Cancer Prev 2015;16(12):4821-4. doi: 10.7314/apjcp.2015.16.12.4821. PMID: 26163597
NEDD9 overexpression correlates with the progression and prognosis in gastric carcinoma.
Shi R, Wang L, Wang T, Xu J, Wang F, Xu M
Med Oncol 2014 Mar;31(3):852. Epub 2014 Jan 28 doi: 10.1007/s12032-014-0852-4. PMID: 24469954
Gastric carcinoma.
Fuchs CS, Mayer RJ
N Engl J Med 1995 Jul 6;333(1):32-41. doi: 10.1056/NEJM199507063330107. PMID: 7776992

Clinical prediction guides

Identifying mitophagy-related genes as prognostic biomarkers and therapeutic targets of gastric carcinoma by integrated analysis of single-cell and bulk-RNA sequencing data.
Wang Z, Chen C, Ai J, Shu J, Ding Y, Wang W, Gao Y, Jia Y, Qin Y
Comput Biol Med 2023 Sep;163:107227. Epub 2023 Jul 3 doi: 10.1016/j.compbiomed.2023.107227. PMID: 37413850
Development and Validation of a Computed Tomography-Based Radiomics Signature to Predict Response to Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer.
Wang W, Peng Y, Feng X, Zhao Y, Seeruttun SR, Zhang J, Cheng Z, Li Y, Liu Z, Zhou Z
JAMA Netw Open 2021 Aug 2;4(8):e2121143. doi: 10.1001/jamanetworkopen.2021.21143. PMID: 34410397Free PMC Article
Assessment of Epinephrine and Norepinephrine in Gastric Carcinoma.
Mehedințeanu AM, Sfredel V, Stovicek PO, Schenker M, Târtea GC, Istrătoaie O, Ciurea AM, Vere CC
Int J Mol Sci 2021 Feb 18;22(4) doi: 10.3390/ijms22042042. PMID: 33670813Free PMC Article
Non-malignant Helicobacter pylori-Associated Diseases.
Falkeis-Veits C, Vieth M
Adv Exp Med Biol 2019;1149:121-134. doi: 10.1007/5584_2019_362. PMID: 31016630
Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota.
Ferreira RM, Pereira-Marques J, Pinto-Ribeiro I, Costa JL, Carneiro F, Machado JC, Figueiredo C
Gut 2018 Feb;67(2):226-236. Epub 2017 Nov 4 doi: 10.1136/gutjnl-2017-314205. PMID: 29102920Free PMC Article

Recent systematic reviews

Clinicopathological Characteristics and Risk Factors of Young-Onset Gastric Carcinoma: A Systematic Review and Meta-analysis.
Li Y, Hahn AI, Laszkowska M, Jiang F, Zauber AG, Leung WK
Clin Transl Gastroenterol 2024 Jun 1;15(6):e1. doi: 10.14309/ctg.0000000000000714. PMID: 38717039Free PMC Article
Prognostic Implication of EBV Infection in Gastric Carcinomas: A Systematic Review and Meta-Analysis.
Pyo JS, Kim NY, Kang DW
Medicina (Kaunas) 2023 Apr 25;59(5) doi: 10.3390/medicina59050834. PMID: 37241066Free PMC Article
Estimating the Global Burden of Epstein-Barr Virus-Associated Gastric Cancer: A Systematic Review and Meta-Analysis.
Hirabayashi M, Georges D, Clifford GM, de Martel C
Clin Gastroenterol Hepatol 2023 Apr;21(4):922-930.e21. Epub 2022 Aug 10 doi: 10.1016/j.cgh.2022.07.042. PMID: 35963539
Perforated Gastric Cancer: A Systematic Review.
Melloni M, Bernardi D, Asti E, Bonavina L
J Laparoendosc Adv Surg Tech A 2020 Feb;30(2):156-162. Epub 2019 Sep 23 doi: 10.1089/lap.2019.0507. PMID: 31545122
Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.
Mocellin S, Verdi D, Pooley KA, Nitti D
Gut 2015 Aug;64(8):1209-19. Epub 2015 Mar 2 doi: 10.1136/gutjnl-2015-309168. PMID: 25731870

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