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Links from GEO DataSets

Items: 1 to 20 of 51

1.
Full record GDS2430

Monocyte differentiation to macrophage and subsequent polarization (HG-U133B)

Analysis of monocytes (MCs) treated with M-CSF to induce differentiation into macrophages (MPs), and mature MPs treated with either IFN-gamma and LPS or IL-4 to induce polarization to M1 or M2 cells, respectively. Results provide insight into MC to MP differentiation and polarized activation.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 development stage sets
Platform:
GPL97
Series:
GSE5099
15 Samples
Download data: CEL
DataSet
Accession:
GDS2430
ID:
2430
2.
Full record GDS4168

Chronic lymphocytic leukemia: peripheral blood B cells (HG-U133B)

Analysis of peripheral blood B cells isolated from 41 untreated chronic lymphocytic leukemia (CLL) patients and 11 age-matched control subjects. B-cell CLL is the most common type of leukemia, mainly affecting adults. Results provide insight into molecular mechanisms underlying CLL pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL97
Series:
GSE22529
52 Samples
Download data: CEL
3.
Full record GDS4146

Subcutaneous Interferon-beta-1b treatment in relapsing-remitting multiple sclerosis (U133 B): peripheral mononuclear blood cells

Temporal analysis of PBMCs collected from 25 German relapsing-remitting multiple sclerosis patients treated with recombinant interferon-beta-1b (rIFN-β-1b, 250 µg every other day) for 2 years. Results provide insight into molecular mechanisms of IFN-b action.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 gender, 5 time sets
Platform:
GPL97
Series:
GSE24427
125 Samples
Download data: CEL
4.
Full record GDS3875

Diabetic children: peripheral blood mononuclear cells (U133B)

Analysis of PBMCs from children (2-18 years) with newly diagnosed type 1 or 2 diabetes (T1D or T2D). One and 4 month samples were obtained from 20 of the T1D patients. Results provide insight into molecular mechanisms that distinguish T1D and T2D and those that are common to both forms of diabetes.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 2 gender, 4 time sets
Platform:
GPL97
Series:
GSE9006
117 Samples
Download data: CEL
DataSet
Accession:
GDS3875
ID:
3875
5.
Full record GDS3851

Smooth muscle cell cord morphogenesis (HG-U133B)

Analysis of HITC6 vascular smooth muscle cells (SMC) before and after serum withdrawal-induced formation of cords showing end-to-end and side-to-side SMC assemblies that approximate the association of SMCs in the arterial media. Results provide insight into molecular basis of SMC cord morphogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 time sets
Platform:
GPL97
Series:
GSE21363
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3851
ID:
3851
6.
Full record GDS3570

VEGF-A effect on endothelial cell line: time course (HG-U133B)

Analysis of umbilical vein endothelial cells (HUVEC) treated with VEGF-A for up to 6 hours in vitro. VEGF-A is a major trigger of vasculogenesis and physiologic angiogenesis. Results provide insight into the molecular mechanisms underlying the vasculogenic and angiogenic activity of VEGF-A.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 5 time sets
Platform:
GPL97
Series:
GSE10778
5 Samples
Download data: CEL, CHP
7.
Full record GDS3560

Occupational benzene exposure: peripheral blood mononuclear cells (HG-U133B)

Analysis of peripheral blood mononuclear cells from shoe factory workers exposed to benzene. Benzene is a leukemogen. Results provide insight into molecular mechanisms of benzene carcinogenicity.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL97
Series:
GSE9569
16 Samples
Download data: CEL
8.
Full record GDS3498

Interleukin-12 effect on peripheral blood mononuclear cells (HG-U133B)

Analysis of cultured peripheral blood mononuclear cells (PBMCs) stimulated with interleukin-12 (IL-12). PBMCs obtained from 7 donors. IL-12 plays a central role in adaptive and innate immunity. Results provide further insight into the effects of IL-12 on the immune response.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 7 individual sets
Platform:
GPL97
Series:
GSE12839
14 Samples
Download data: CEL
9.
Full record GDS3475

Limb girdle muscular dystrophy 2A (HG-U133B)

Analysis of skeletal muscles from patients with limb girdle muscular dystrophy 2A (LGMD2A). LGMD2A is a recessive genetic disorder caused by mutations in calpain 3 (CAPN3). Results provide insight into the molecular pathogenesis of LGMD2A.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL97
Series:
GSE11681
17 Samples
Download data: CEL
10.
Full record GDS3402

Two distinct isogenic mesenchymal stem/stromal cell populations from umbilical cord blood (HG-U133B)

Comparison of UCB1 and UCB2 cells, two distinct isogenic mesenchymal stem/stromal cell (MSC) populations isolated from umbilical cord blood. UCB1 and UCB2 display phenotypic differences. Results provide insight into the molecular basis of the phenotypic heterogeneity among MSC populations.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 specimen sets
Platform:
GPL97
Series:
GSE6029
9 Samples
Download data: CEL
DataSet
Accession:
GDS3402
ID:
3402
11.
Full record GDS3308

Cytogenetically normal acute myeloid leukemia_training set (HG-U133B)

Analysis of mononuclear cells from bone marrow or peripheral blood from a training set of 163 adult patients with cytogenetically normal acute myeloid leukemia (CN-AML). Patients with CN-AML show heterogeneous treatment outcomes. Results provide insight into a prognostic gene signature for CN-AML.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 tissue sets
Platform:
GPL97
Series:
GSE12417
163 Samples
Download data: CEL
12.
Full record GDS3129

Parkinson's disease: substantia nigra (HG-U133B)

Analysis of medial and lateral substantia nigras (SNs) from post-mortem brain samples obtained from individuals with sporadic Parkinson's disease (PD). The SN exhibits extensive tissue damage in PD. Results provide insight into the pathogenesis of PD.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 23 individual, 3 tissue sets
Platform:
GPL97
Series:
GSE8397
47 Samples
Download data: CEL
DataSet
Accession:
GDS3129
ID:
3129
13.
Full record GDS2881

Clear cell renal cell carcinoma (HB-U133B)

Analysis of patient matched normal and stage 1 or stage 2 clear cell renal cell carcinoma (cRCC) tumors. Results provide insight into the molecular pathogenesis of cRCC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 10 individual sets
Platform:
GPL97
Series:
GSE6344
20 Samples
Download data: CEL
14.
Full record GDS2855

Various muscle diseases (HG-U133B)

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 11 disease state sets
Platform:
GPL97
Series:
GSE3307
119 Samples
Download data: CEL
15.
Full record GDS2834

Polyomavirus JCV resistant glial cell line (HG-U133B)

Analysis of SVGR2 glial cells resistant to the human polyomavirus JCV, the causative agent of progressive multifocal leukoencephalopathy. SVGR2 cells are derived from susceptible glial cells (SVG-A). Results provide insight into the molecular mechanisms underlying susceptibility to JCV infection.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 cell type sets
Platform:
GPL97
Series:
GSE7819
6 Samples
Download data: CEL, CHP, EXP
16.
Full record GDS2788

LIM-only protein 4 induction effect on breast cancer cell line (HG-U133B)

Analysis of breast cancer MCF-7 cells following the induction of expression of nuclear LIM-only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in promoting tumor formation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL97
Series:
GSE7382
6 Samples
Download data: CEL
DataSet
Accession:
GDS2788
ID:
2788
17.
Full record GDS2745

Dioxin effect on breast cancer cell line (HG-U133B)

Analysis of MCF-7 breast cancer cells treated with 100 nM dioxin. Although dioxin is causative for many types of cancers, low exposure to dioxin is associated with a decreased incidence of breast carcinoma. Results provide insight into the molecular basis of this protective effect.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL97
Series:
GSE7765
6 Samples
Download data: CEL, CHP, EXP
DataSet
Accession:
GDS2745
ID:
2745
18.
Full record GDS2656

Fetal and adult reticulocytes (HG-U133B)

Analysis of circulating blood reticulocytes from umbilical cords and normal adults. Reticulocytes are immature red blood cells containing residual RNA. Results provide insight into the molecular basis of terminal erythroid differentiation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 development stage sets
Platform:
GPL97
Series:
GSE6236
28 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2656
ID:
2656
19.
Full record GDS2618

Tumorigenic breast cancer cells (HG-U133B)

Analysis of breast cancer cells that have high tumorigenic capacity. These cells express CD44 and low or undetectable levels of CD24. Results used to define a gene expression signature associated with metastasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL97
Series:
GSE6883
12 Samples
Download data: CEL
DataSet
Accession:
GDS2618
ID:
2618
20.
Full record GDS2529

Basal plate of the placenta from midgestation to term (HG-U133B)

Analysis of the basal plate of the placenta from midgestation to term. The basal plate is the region where maternal and fetal cells coexist. Its proper formation is required for pregnancy. Results provide insight into the molecular basis of the unique cell-cell interactions in the basal plate.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 12 age, 2 development stage sets
Platform:
GPL97
Series:
GSE5999
36 Samples
Download data: CEL
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