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Benign vascular tumor

MedGen UID:: 235124
•Concept ID:: C1377916
•: Neoplastic Process

Synonyms:	Benign Vascular Neoplasm; Benign Vascular Tumor; benign vascular tumor; Vascular Neoplasms, Benign

Monarch Initiative:	MONDO:0971115

Definition

A mesenchymal neoplasm that arises from vascular tissue usually of the skin. It is characterized by the presence of vascular channel formation and endothelial cells. There is no evidence of atypical or malignant cytological and architectural features, invasive features, or metastases. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign vascular tumor

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Benign neoplasm
        Benign connective and soft tissue neoplasm
        Benign vascular tumor
        Benign blood vessel neoplasm
        Angiomatosis
        Angioosteohypertrophic syndrome
        Bacillary angiomatosis
        Breast angiomatosis
        Kasabach-Merritt syndrome
        Sturge-Weber syndrome
        Von Hippel-Lindau syndrome
        Hemangioma
        Acquired hemangioma
        Arachnoid hemangiomatosis
        Bladder Hemangioma
        Bone Hemangioma
        Breast hemangioma
        Capillary hemangioma
        Cardiac hemangioma
        Cavernous hemangioma
        Central nervous system hemangioma
        Central Nervous System Venous Angioma
        Chorangioma
        Choroidal hemangioma
        Congenital hemangioma
        Conjunctival Hemangioma
        Deep hemangioma
        Digestive System Hemangioma
        Epithelioid hemangioma
        Esophageal hemangioma
        Glabellar hemangioma
        Glomeruloid hemangioma
        Hemangioendothelioma
        Hemangioma of gingiva
        Hemangioma of orbit
        Hemangioma of peripheral nerve
        Hemangioma of subcutaneous tissue
        Hemangiomatosis
        Hobnail hemangioma
        Intra-abdominal hemangioma
        Intracranial hemangioma
        Intrathoracic hemangioma
        Kidney Hemangioma
        Labial hemangioma
        Laryngeal hemangioma
        Lumbosacral hemangioma
        Mediastinal Hemangioma
        Mucous Membrane Hemangioma
        Paraspinal hemangioma
        Paratesticular Hemangioma
        Perineal hemangioma
        Prostate Hemangioma
        Retropharyngeal hemangioma
        Salivary Gland Hemangioma
        Sinonasal Hemangioma
        Skin hemangioma
        Spindle cell hemangioma
        Splenic hemangioma
        Subglottic hemangioma
        Supraglottic hemangioma
        Synovial angioma
        Thyroid Gland Hemangioma
        Tufted angioma of skin
        Venous hemangioma
        Visceral hemangioma
        Vulvar hemangioma
        Benign Lymphatic Vessel Neoplasm
        Lymphangioma
        Cavernous lymphangioma
        Conjunctival Lymphangioma
        Cystic hygroma
        Diffuse lymphatic malformation
        Gastric Lymphangioma
        Gorham-Stout disease
        Hemolymphangioma
        Intra-Abdominal Lymphangioma
        Kidney Lymphangioma
        Lymphangioendothelioma
        Lymphangioma Circumscriptum
        Lymphangioma of the orbit
        Lymphedema-posterior choanal atresia syndrome
        Mediastinal cystic lymphangioma
        Mediastinal Lymphangioma
        Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome
        Parotid Gland Lymphangioma
        Skin lymphangioma
        Thyroid Gland Lymphangioma
        Benign Skin Vascular Neoplasm
        Benign Thyroid Gland Vascular Neoplasm

Professional guidelines

PubMed

Update on the diagnosis and treatment of choroidal hemangioma.

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411

Medical Management of Infantile Hemangiomas: An Update.

Colmant C, Powell J
Paediatr Drugs 2022 Jan;24(1):29-43. Epub 2021 Oct 22 doi: 10.1007/s40272-021-00477-9. PMID: 34677814

Circumscribed choroidal hemangioma: An overview of clinical manifestation, diagnosis and management.

Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430 Free PMC Article

See all (14)

Recent clinical studies

Etiology

Oral atenolol compared to oral propranolol for infantile hemangioma.

Meza Viteri V, Aranibar L
Medwave 2023 Dec 7;23(11):e2753. doi: 10.5867/medwave.2023.11.2753. PMID: 38061014

Our experience with propranolol for infantile hemangioma.

Wu Y, Zhao P, Song W, Lu W, Dai T, Wang L
Skin Res Technol 2023 Apr;29(4):e13310. doi: 10.1111/srt.13310. PMID: 37113082 Free PMC Article

Severe hypoglycemia in propranolol treatment for infantile hemangiomas.

Morimoto A, Ozeki M, Sasaki S, Baba N, Kuwano Y, Kaneko T
Pediatr Int 2022 Jan;64(1):e15278. doi: 10.1111/ped.15278. PMID: 35972062 Free PMC Article

Examination of oral hemangiomas by intraoral ultrasonography.

Derindağ G, Sarıca İ, Çağlayan F
Oral Radiol 2021 Oct;37(4):687-692. Epub 2021 Mar 3 doi: 10.1007/s11282-021-00511-z. PMID: 33656695

Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options.

Schmid I, Klenk AK, Sparber-Sauer M, Koscielniak E, Maxwell R, Häberle B
World J Pediatr 2018 Aug;14(4):322-329. Epub 2018 Jul 27 doi: 10.1007/s12519-018-0171-5. PMID: 30054848

See all (41)

Diagnosis

Update on the diagnosis and treatment of choroidal hemangioma.

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411

Nasal Septal Angiofibroma.

Thobejane O, Maharaj S
Ear Nose Throat J 2023 Oct;102(10):NP483-NP484. Epub 2021 Jun 16 doi: 10.1177/01455613211026517. PMID: 34134540

Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options.

Schmid I, Klenk AK, Sparber-Sauer M, Koscielniak E, Maxwell R, Häberle B
World J Pediatr 2018 Aug;14(4):322-329. Epub 2018 Jul 27 doi: 10.1007/s12519-018-0171-5. PMID: 30054848

Choroidal hemangioma.

Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200

Circumscribed choroidal hemangioma.

Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

See all (157)

Therapy

Infantile hemangioma: the common and enigmatic vascular tumor.

Holm A, Mulliken JB, Bischoff J
J Clin Invest 2024 Apr 15;134(8) doi: 10.1172/JCI172836. PMID: 38618963 Free PMC Article

Oral atenolol compared to oral propranolol for infantile hemangioma.

Meza Viteri V, Aranibar L
Medwave 2023 Dec 7;23(11):e2753. doi: 10.5867/medwave.2023.11.2753. PMID: 38061014

Medical Management of Infantile Hemangiomas: An Update.

Colmant C, Powell J
Paediatr Drugs 2022 Jan;24(1):29-43. Epub 2021 Oct 22 doi: 10.1007/s40272-021-00477-9. PMID: 34677814

Proanthocyanidins as a Potential Novel Way for the Treatment of Hemangioma.

Tang R, Xian D, Xu J, Peng H, Pan S, Zhong J
Biomed Res Int 2021;2021:5695378. Epub 2021 Jan 2 doi: 10.1155/2021/5695378. PMID: 33490272 Free PMC Article

Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options.

Schmid I, Klenk AK, Sparber-Sauer M, Koscielniak E, Maxwell R, Häberle B
World J Pediatr 2018 Aug;14(4):322-329. Epub 2018 Jul 27 doi: 10.1007/s12519-018-0171-5. PMID: 30054848

See all (26)

Prognosis

Update on the diagnosis and treatment of choroidal hemangioma.

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411

Medical Management of Infantile Hemangiomas: An Update.

Colmant C, Powell J
Paediatr Drugs 2022 Jan;24(1):29-43. Epub 2021 Oct 22 doi: 10.1007/s40272-021-00477-9. PMID: 34677814

Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options.

Schmid I, Klenk AK, Sparber-Sauer M, Koscielniak E, Maxwell R, Häberle B
World J Pediatr 2018 Aug;14(4):322-329. Epub 2018 Jul 27 doi: 10.1007/s12519-018-0171-5. PMID: 30054848

Evolution of hemangioma endothelium.

Kleiman A, Keats EC, Chan NG, Khan ZA
Exp Mol Pathol 2012 Oct;93(2):264-72. Epub 2012 May 4 doi: 10.1016/j.yexmp.2012.04.020. PMID: 22565125

Choroidal hemangioma.

Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200

See all (35)

Clinical prediction guides

Oral atenolol compared to oral propranolol for infantile hemangioma.

Meza Viteri V, Aranibar L
Medwave 2023 Dec 7;23(11):e2753. doi: 10.5867/medwave.2023.11.2753. PMID: 38061014

Imaging findings of retroperitoneal anastomosing hemangioma: a case report and literature review.

Xue X, Song M, Xiao W, Chen F, Huang Q
BMC Urol 2022 May 22;22(1):77. doi: 10.1186/s12894-022-01022-7. PMID: 35599311 Free PMC Article

Medical Management of Infantile Hemangiomas: An Update.

Colmant C, Powell J
Paediatr Drugs 2022 Jan;24(1):29-43. Epub 2021 Oct 22 doi: 10.1007/s40272-021-00477-9. PMID: 34677814

Examination of oral hemangiomas by intraoral ultrasonography.

Derindağ G, Sarıca İ, Çağlayan F
Oral Radiol 2021 Oct;37(4):687-692. Epub 2021 Mar 3 doi: 10.1007/s11282-021-00511-z. PMID: 33656695

Circumscribed choroidal hemangioma.

Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

See all (28)

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Benign vascular tumor

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

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Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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