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Choroidal hemangioma

MedGen UID:
83424
Concept ID:
C0346390
Neoplastic Process
Synonym: Choroidal hemangiomata
SNOMED CT: Choroidal hemangioma (255022003); Hemangioma of choroid (255022003)
 
HPO: HP:0007872
Monarch Initiative: MONDO:0021542

Definition

The presence of multiple hemangiomas in the choroid. These are generally reddish or orange or can have increased pigmentation maiking them difficult to distinguish from choroidal melanomas. [from HPO]

Term Hierarchy

Conditions with this feature

Sturge-Weber syndrome
MedGen UID:
21361
Concept ID:
C0038505
Disease or Syndrome
Sturge-Weber syndrome (SWS) is characterized by an intracranial vascular anomaly, leptomeningeal angiomatosis, most often involving the occipital and posterior parietal lobes. The most common symptoms and signs are facial cutaneous vascular malformations (port-wine stains), seizures, and glaucoma. Stasis results in ischemia underlying the leptomeningeal angiomatosis, leading to calcification and laminar cortical necrosis. The clinical course is highly variable and some children experience intractable seizures, mental retardation, and recurrent stroke-like episodes (review by Thomas-Sohl et al., 2004).

Professional guidelines

PubMed

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Kumar A, Shankar S, Singh A, Mishra S, Kumar P, Arora A
Photodiagnosis Photodyn Ther 2022 Sep;39:103000. Epub 2022 Jul 3 doi: 10.1016/j.pdpdt.2022.103000. PMID: 35793781
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article

Recent clinical studies

Etiology

Koç İ, Yücel Gençoğlu A, Yücekul B, Deliktaş Ö, Öztürk E, Kiratli H
Int Ophthalmol 2024 Jul 2;44(1):307. doi: 10.1007/s10792-024-03238-y. PMID: 38955894
Franco JJ, Liu KX, Ioakeim-Ioannidou M, Davila JR, Chen YL, Kim IK, Gragoudas ES, Mukai S, MacDonald SM
Pediatr Blood Cancer 2022 Dec;69(12):e29925. Epub 2022 Aug 21 doi: 10.1002/pbc.29925. PMID: 35989464
Merritt H, Pfeiffer ML, Phillips ME, Richani K
Orbit 2017 Feb;36(1):48-51. Epub 2017 Feb 1 doi: 10.1080/01676830.2017.1279643. PMID: 28146369
Kim YT, Kang SW, Lee JI
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1399-404. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.016. PMID: 20950946
Celebi S, Alagöz G, Aykan U
Eur J Ophthalmol 2000 Jul-Sep;10(3):239-43. doi: 10.1177/112067210001000308. PMID: 11071032

Diagnosis

Torres G, Kini AT, Al Othman B, Lee AG
J Neuroophthalmol 2020 Jun;40(2):262-264. doi: 10.1097/WNO.0000000000000778. PMID: 30893269
Seregard S, Pelayes DE, Singh AD
Dev Ophthalmol 2013;52:36-57. Epub 2013 Aug 26 doi: 10.1159/000351055. PMID: 23989126
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933
Pitta CG, Shingleton BJ, Harris PJ, Regan CD
Am J Ophthalmol 1979 Oct;88(4):698-701. doi: 10.1016/0002-9394(79)90668-8. PMID: 574362

Therapy

Kalantary A, Halbert A, Franchina M, Heath Jeffery RC, O'Day R, Chen FK
JAMA Ophthalmol 2024 Jun 1;142(6):585-587. doi: 10.1001/jamaophthalmol.2024.0854. PMID: 38635233
Zhang W, Peng J, Zhao P
Ophthalmology 2024 Aug;131(8):891. Epub 2023 Oct 19 doi: 10.1016/j.ophtha.2023.09.017. PMID: 37855777
Jorge R, Chaves L, Cunha ADS, Correa ZM
Retin Cases Brief Rep 2022 Jan 1;16(1):106-110. doi: 10.1097/ICB.0000000000000917. PMID: 31517744
Battaglia Parodi M, La Spina C, Berchicci L, Petruzzi G, Bandello F
Dev Ophthalmol 2016;55:330-6. Epub 2015 Oct 26 doi: 10.1159/000434704. PMID: 26501167
Kim YT, Kang SW, Lee JI
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1399-404. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.016. PMID: 20950946

Prognosis

Koç İ, Yücel Gençoğlu A, Yücekul B, Deliktaş Ö, Öztürk E, Kiratli H
Int Ophthalmol 2024 Jul 2;44(1):307. doi: 10.1007/s10792-024-03238-y. PMID: 38955894
Ganz JC
Prog Brain Res 2022;268(1):315-327. Epub 2021 Dec 14 doi: 10.1016/bs.pbr.2021.10.039. PMID: 35074088
Merritt H, Pfeiffer ML, Phillips ME, Richani K
Orbit 2017 Feb;36(1):48-51. Epub 2017 Feb 1 doi: 10.1080/01676830.2017.1279643. PMID: 28146369
Kim YT, Kang SW, Lee JI
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1399-404. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.016. PMID: 20950946
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200

Clinical prediction guides

Franco JJ, Liu KX, Ioakeim-Ioannidou M, Davila JR, Chen YL, Kim IK, Gragoudas ES, Mukai S, MacDonald SM
Pediatr Blood Cancer 2022 Dec;69(12):e29925. Epub 2022 Aug 21 doi: 10.1002/pbc.29925. PMID: 35989464
Jorge R, Chaves L, Cunha ADS, Correa ZM
Retin Cases Brief Rep 2022 Jan 1;16(1):106-110. doi: 10.1097/ICB.0000000000000917. PMID: 31517744
Stehouwer M, Schlingemann RO, Verbraak FD
Acta Ophthalmol 2020 Nov;98(7):679-686. Epub 2020 Apr 14 doi: 10.1111/aos.14409. PMID: 32286734Free PMC Article
Kim YT, Kang SW, Lee JI
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1399-404. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.016. PMID: 20950946
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

Recent systematic reviews

Zamir A, Hussain I, Ur Rehman A, Ashraf W, Imran I, Saeed H, Majeed A, Alqahtani F, Rasool MF
Clin Pharmacokinet 2022 Aug;61(8):1095-1114. Epub 2022 Jun 28 doi: 10.1007/s40262-022-01145-y. PMID: 35764772

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