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Alphavirus infectious disease

MedGen UID:
64650
Concept ID:
C0206752
Disease or Syndrome
Synonyms: Alpha Virus Infection; Alpha Virus Infections; Alphavirus Infection; Alphavirus Infections; Infection, Alphavirus; Infections, Alphavirus; Virus Infection, Alpha
SNOMED CT: Alphavirus disease (4003003); Disease caused by Alphavirus (4003003)
 
Monarch Initiative: MONDO:0005643

Definition

Virus diseases caused by members of the alphavirus genus of the family togaviridae. [from MONDO]

Professional guidelines

PubMed

Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Sutaria RB, Amaral JK, Schoen RT
Curr Opin Rheumatol 2018 May;30(3):256-263. doi: 10.1097/BOR.0000000000000486. PMID: 29389830
Zaid A, Gérardin P, Taylor A, Mostafavi H, Malvy D, Mahalingam S
Arthritis Rheumatol 2018 Apr;70(4):484-495. Epub 2018 Mar 23 doi: 10.1002/art.40403. PMID: 29287308

Recent clinical studies

Etiology

Li W, Plante JA, Lin C, Basu H, Plung JS, Fan X, Boeckers JM, Oros J, Buck TK, Anekal PV, Hanson WA, Varnum H, Wells A, Mann CJ, Tjang LV, Yang P, Reyna RA, Mitchell BM, Shinde DP, Walker JL, Choi SY, Brusic V, Llopis PM, Weaver SC, Umemori H, Chiu IM, Plante KS, Abraham J
Nature 2024 Aug;632(8025):614-621. Epub 2024 Jul 24 doi: 10.1038/s41586-024-07740-2. PMID: 39048821Free PMC Article
Bartholomeeusen K, Daniel M, LaBeaud DA, Gasque P, Peeling RW, Stephenson KE, Ng LFP, Ariën KK
Nat Rev Dis Primers 2023 Apr 6;9(1):17. doi: 10.1038/s41572-023-00429-2. PMID: 37024497Free PMC Article
Simon F, Caumes E, Jelinek T, Lopez-Velez R, Steffen R, Chen LH
J Travel Med 2023 Apr 5;30(2) doi: 10.1093/jtm/taad008. PMID: 36648431Free PMC Article
Sharma V, Sharma A
Best Pract Res Clin Rheumatol 2022 Mar;36(1):101736. Epub 2021 Dec 31 doi: 10.1016/j.berh.2021.101736. PMID: 34974970
Tanay A
Curr Opin Rheumatol 2017 Jul;29(4):389-393. doi: 10.1097/BOR.0000000000000396. PMID: 28376065

Diagnosis

Sharma V, Sharma A
Best Pract Res Clin Rheumatol 2022 Mar;36(1):101736. Epub 2021 Dec 31 doi: 10.1016/j.berh.2021.101736. PMID: 34974970
Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Mejía CR, López-Vélez R
Reumatol Clin (Engl Ed) 2018 Mar-Apr;14(2):97-105. Epub 2017 Mar 30 doi: 10.1016/j.reuma.2017.01.006. PMID: 28365217
Burnett MW
J Spec Oper Med 2014 Winter;14(4):129-130. doi: 10.55460/8H36-WO5P. PMID: 25399382
Caglioti C, Lalle E, Castilletti C, Carletti F, Capobianchi MR, Bordi L
New Microbiol 2013 Jul;36(3):211-27. Epub 2013 Jun 30 PMID: 23912863

Therapy

Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP
Ann N Y Acad Sci 2023 Mar;1521(1):46-66. Epub 2023 Jan 25 doi: 10.1111/nyas.14957. PMID: 36697369Free PMC Article
Sharma V, Sharma A
Best Pract Res Clin Rheumatol 2022 Mar;36(1):101736. Epub 2021 Dec 31 doi: 10.1016/j.berh.2021.101736. PMID: 34974970
de Alwis R, Gan ES, Chen S, Leong YS, Tan HC, Zhang SL, Yau C, Low JGH, Kalimuddin S, Matsuda D, Allen EC, Hartman P, Park KJ, Alayyoubi M, Bhaskaran H, Dukanovic A, Bao Y, Clemente B, Vega J, Roberts S, Gonzalez JA, Sablad M, Yelin R, Taylor W, Tachikawa K, Parker S, Karmali P, Davis J, Sullivan BM, Sullivan SM, Hughes SG, Chivukula P, Ooi EE
Mol Ther 2021 Jun 2;29(6):1970-1983. Epub 2021 Apr 5 doi: 10.1016/j.ymthe.2021.04.001. PMID: 33823303Free PMC Article
Blakney AK, McKay PF, Bouton CR, Hu K, Samnuan K, Shattock RJ
Mol Ther 2021 Mar 3;29(3):1174-1185. Epub 2020 Dec 21 doi: 10.1016/j.ymthe.2020.11.011. PMID: 33352107Free PMC Article
Pathak H, Mohan MC, Ravindran V
Clin Med (Lond) 2019 Sep;19(5):381-385. doi: 10.7861/clinmed.2019-0035. PMID: 31530685Free PMC Article

Prognosis

Rawle DJ, Hugo LE, Cox AL, Devine GJ, Suhrbier A
Nat Rev Immunol 2024 Sep;24(9):621-636. Epub 2024 Apr 3 doi: 10.1038/s41577-024-01016-6. PMID: 38570719
Baxter VK, Heise MT
Mamm Genome 2018 Aug;29(7-8):408-424. Epub 2018 Aug 27 doi: 10.1007/s00335-018-9776-1. PMID: 30151711Free PMC Article
Tanay A
Curr Opin Rheumatol 2017 Jul;29(4):389-393. doi: 10.1097/BOR.0000000000000396. PMID: 28376065
MacFadden DR, Bogoch II
CMAJ 2014 Jul 8;186(10):775. Epub 2014 Jun 9 doi: 10.1503/cmaj.140031. PMID: 24914111Free PMC Article
Suhrbier A, Jaffar-Bandjee MC, Gasque P
Nat Rev Rheumatol 2012 May 8;8(7):420-9. doi: 10.1038/nrrheum.2012.64. PMID: 22565316

Clinical prediction guides

Rawle DJ, Hugo LE, Cox AL, Devine GJ, Suhrbier A
Nat Rev Immunol 2024 Sep;24(9):621-636. Epub 2024 Apr 3 doi: 10.1038/s41577-024-01016-6. PMID: 38570719
Blakney AK, McKay PF, Bouton CR, Hu K, Samnuan K, Shattock RJ
Mol Ther 2021 Mar 3;29(3):1174-1185. Epub 2020 Dec 21 doi: 10.1016/j.ymthe.2020.11.011. PMID: 33352107Free PMC Article
Waggoner JJ, Pinsky BA
Expert Rev Anti Infect Ther 2015 Mar;13(3):291-3. Epub 2014 Dec 24 doi: 10.1586/14787210.2015.995634. PMID: 25537007Free PMC Article
Rudolph KE, Lessler J, Moloney RM, Kmush B, Cummings DA
Am J Trop Med Hyg 2014 May;90(5):882-91. Epub 2014 Mar 17 doi: 10.4269/ajtmh.13-0403. PMID: 24639305Free PMC Article
Caglioti C, Lalle E, Castilletti C, Carletti F, Capobianchi MR, Bordi L
New Microbiol 2013 Jul;36(3):211-27. Epub 2013 Jun 30 PMID: 23912863

Recent systematic reviews

Contopoulos-Ioannidis D, Newman-Lindsay S, Chow C, LaBeaud AD
PLoS Negl Trop Dis 2018 Jun;12(6):e0006510. Epub 2018 Jun 13 doi: 10.1371/journal.pntd.0006510. PMID: 29897898Free PMC Article
Mehta R, Gerardin P, de Brito CAA, Soares CN, Ferreira MLB, Solomon T
Rev Med Virol 2018 May;28(3):e1978. Epub 2018 Apr 19 doi: 10.1002/rmv.1978. PMID: 29671914Free PMC Article
Badawi A, Ryoo SG, Vasileva D, Yaghoubi S
Int J Infect Dis 2018 Feb;67:107-113. Epub 2017 Dec 20 doi: 10.1016/j.ijid.2017.12.018. PMID: 29277382Free PMC Article
Humphrey JM, Cleton NB, Reusken CBEM, Glesby MJ, Koopmans MPG, Abu-Raddad LJ
PLoS Negl Trop Dis 2017 Jun;11(6):e0005707. Epub 2017 Jun 26 doi: 10.1371/journal.pntd.0005707. PMID: 28651007Free PMC Article
Rudolph KE, Lessler J, Moloney RM, Kmush B, Cummings DA
Am J Trop Med Hyg 2014 May;90(5):882-91. Epub 2014 Mar 17 doi: 10.4269/ajtmh.13-0403. PMID: 24639305Free PMC Article

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