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Benign neoplasm of cerebrum

MedGen UID:
195785
•Concept ID:
C0686378
•
Neoplastic Process
Synonyms: Benign Cerebral Hemispheric Neoplasm; benign cerebral hemispheric neoplasm; Benign Cerebral Hemispheric Tumor; benign cerebral hemispheric tumor; benign cerebral hemispheric tumour; Benign Cerebral Neoplasm; benign cerebral neoplasm; Benign cerebral tumor; Benign Cerebral Tumor; benign cerebral tumor; benign cerebral tumour; Benign Neoplasm of Cerebral Hemispheres; benign neoplasm of cerebral hemispheres; Benign Neoplasm of Cerebrum; benign neoplasm of cerebrum; Benign Neoplasm of the Cerebral Hemispheres; benign neoplasm of the cerebral hemispheres; Benign Neoplasm of the Cerebrum; benign neoplasm of the cerebrum; Benign Tumor of Cerebral Hemispheres; benign tumor of cerebral hemispheres; Benign Tumor of Cerebrum; benign tumor of cerebrum; Benign Tumor of the Cerebral Hemispheres; benign tumor of the cerebral hemispheres; Benign Tumor of the Cerebrum; benign tumor of the cerebrum; benign tumour of cerebral hemispheres; benign tumour of cerebrum; benign tumour of the cerebral hemispheres; benign tumour of the cerebrum; telencephalon benign neoplasm
SNOMED CT: Benign neoplasm of cerebrum (275269004); Benign cerebral tumor (275269004)
 
Monarch Initiative: MONDO:0021497

Definition

A neoplasm that arises from the cerebrum and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Hippocampal sparing radiation therapy for brain metastases: treatment techniques and clinical implementation.
Woods K, Shen ZL, Xu Z, Zhang H, Natsuaki Y, Cheng K, Li V, Kim N, Ma L, Chang E
Chin Clin Oncol 2023 Oct;12(5):56. doi: 10.21037/cco-23-73. PMID: 37964545
Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme.
Checa-Chavarria E, Rivero-Buceta E, Sanchez Martos MA, Martinez Navarrete G, Soto-Sánchez C, Botella P, Fernández E
Mol Pharm 2021 Apr 5;18(4):1558-1572. Epub 2021 Mar 1 doi: 10.1021/acs.molpharmaceut.0c00968. PMID: 33645231Free PMC Article
Prenatal diagnosis of hemimegalencephaly revealing tuberous sclerosis complex.
Bruet S, Francannet C, Marguet F, Biard M, Sarret C, Laurichesse Delmas H
Ultrasound Obstet Gynecol 2020 May;55(5):688-689. doi: 10.1002/uog.21874. PMID: 31568608

Recent clinical studies

Etiology

Surgical treatment of tumors of the supplementary motor area.
Alekseev IM, Zuev AA
Zh Vopr Neirokhir Im N N Burdenko 2023;87(1):5-14. doi: 10.17116/neiro2023870115. PMID: 36763548
The transfrontal isthmus approach for insular glioma surgery.
Sun GC, Shu XJ, Zheng XQ, Ma XD, Cheng G, Liu JL, Chen L, Zhang JN
J Neurosurg 2023 Jul 1;139(1):20-28. Epub 2022 Nov 11 doi: 10.3171/2022.8.JNS22923. PMID: 36681987
MRI venous architecture of insula.
Gogia B, Chavali LS, Lang FF, Hayman LA, Rai P, Prabhu SS, Schomer DF, Kumar VA
J Neurol Sci 2018 Jul 15;390:156-161. Epub 2018 Apr 22 doi: 10.1016/j.jns.2018.04.032. PMID: 29801878
Epilepsy related to developmental tumors and malformations of cortical development.
Aronica E, Crino PB
Neurotherapeutics 2014 Apr;11(2):251-68. doi: 10.1007/s13311-013-0251-0. PMID: 24481729Free PMC Article
Supratentorial hemangioblastoma.
Yang B, Luan S, Cao X, Bao W
Neurosciences (Riyadh) 2011 Apr;16(2):150-2. PMID: 21427665

Diagnosis

Sturge-Weber syndrome.
Ho TH, Yang FC, Lin JC, Hsu CH, Lee JT
QJM 2019 Apr 1;112(4):299. doi: 10.1093/qjmed/hcy246. PMID: 30357409
Review of surgical treatment of insular gliomas: challenges and opportunities.
Pitskhelauri DI, Bykanov AE, Zhukov VY, Kachkov IA, Buklina SB, Tonoyan AS
Zh Vopr Neirokhir Im N N Burdenko 2015;79(2):111-116. doi: 10.17116/neiro2015792111-116. PMID: 26182444
Cystic meningioma.
Amin OS, Shwani SS, Khalifa F
BMJ Case Rep 2015 Feb 10;2015 doi: 10.1136/bcr-2014-207690. PMID: 25670784Free PMC Article
The Sylvian fissure, cistern and arachnoid membrane.
Balak N
Br J Neurosurg 2014 Jan;28(1):98-106. Epub 2013 Jul 19 doi: 10.3109/02688697.2013.815324. PMID: 23869573
Subfrontal schwannoma.
Yako K, Morita A, Ueki K, Kirino T
Acta Neurochir (Wien) 2005 Jun;147(6):655-7; discussion 657-8. Epub 2005 Apr 25 doi: 10.1007/s00701-005-0528-0. PMID: 15824881

Therapy

Advances in Radiotherapy for Brain Metastases.
Matsui JK, Perlow HK, Upadhyay R, McCalla A, Raval RR, Thomas EM, Blakaj DM, Beyer SJ, Palmer JD
Surg Oncol Clin N Am 2023 Jul;32(3):569-586. Epub 2023 Apr 4 doi: 10.1016/j.soc.2023.02.007. PMID: 37182993
A Review on the Surgical Management of Insular Gliomas.
Renfrow JJ, Julian BQ, Brown DA, Tatter SB, Laxton AW, Lesser GJ, Strowd RE, Parney IF
Can J Neurol Sci 2023 Jan;50(1):1-9. Epub 2021 Oct 29 doi: 10.1017/cjn.2021.248. PMID: 34711299
Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy.
Jang A, Petrova B, Cheong TC, Zawadzki ME, Jones JK, Culhane AJ, Shipley FB, Chiarle R, Wong ET, Kanarek N, Lehtinen MK
Neuron 2022 Oct 19;110(20):3288-3301.e8. Epub 2022 Sep 6 doi: 10.1016/j.neuron.2022.08.009. PMID: 36070751Free PMC Article
Review of surgical treatment of insular gliomas: challenges and opportunities.
Pitskhelauri DI, Bykanov AE, Zhukov VY, Kachkov IA, Buklina SB, Tonoyan AS
Zh Vopr Neirokhir Im N N Burdenko 2015;79(2):111-116. doi: 10.17116/neiro2015792111-116. PMID: 26182444
Hippocampal-sparing whole-brain radiotherapy: a "how-to" technique using helical tomotherapy and linear accelerator-based intensity-modulated radiotherapy.
Gondi V, Tolakanahalli R, Mehta MP, Tewatia D, Rowley H, Kuo JS, Khuntia D, Tomé WA
Int J Radiat Oncol Biol Phys 2010 Nov 15;78(4):1244-52. doi: 10.1016/j.ijrobp.2010.01.039. PMID: 20598457Free PMC Article

Prognosis

H3 G34-mutant high-grade glioma.
Lim KY, Won JK, Park CK, Kim SK, Choi SH, Kim T, Yun H, Park SH
Brain Tumor Pathol 2021 Jan;38(1):4-13. Epub 2020 Sep 29 doi: 10.1007/s10014-020-00378-8. PMID: 32995948
Supratentorial pediatric cortical ependymomas: a comprehensive retrospective study.
Wang Q, Cheng J, Zhang S, Li Q, Hui X, Ju Y
Neurosurg Rev 2021 Jun;44(3):1543-1551. Epub 2020 Jun 30 doi: 10.1007/s10143-020-01336-w. PMID: 32607870
Supratentorial hemangioblastoma.
Yang B, Luan S, Cao X, Bao W
Neurosciences (Riyadh) 2011 Apr;16(2):150-2. PMID: 21427665
Parietal lipomeningocele--case report.
Yamashita S, Kunishio K, Tamiya T, Nakamura T, Ogawa D, Igawa HH, Kuroda Y, Nagao S
Neurol Med Chir (Tokyo) 2005 Feb;45(2):112-5. doi: 10.2176/nmc.45.112. PMID: 15722612
Gangliogliomas in childhood.
Smith NM, Carli MM, Hanieh A, Clark B, Bourne AJ, Byard RW
Childs Nerv Syst 1992 Aug;8(5):258-62. doi: 10.1007/BF00300792. PMID: 1394264

Clinical prediction guides

The transfrontal isthmus approach for insular glioma surgery.
Sun GC, Shu XJ, Zheng XQ, Ma XD, Cheng G, Liu JL, Chen L, Zhang JN
J Neurosurg 2023 Jul 1;139(1):20-28. Epub 2022 Nov 11 doi: 10.3171/2022.8.JNS22923. PMID: 36681987
Time-to-contact perception in the brain.
Baurès R, Fourteau M, Thébault S, Gazard C, Pasquio L, Meneghini G, Perrin J, Rosito M, Durand JB, Roux FE
J Neurosci Res 2021 Feb;99(2):455-466. Epub 2020 Oct 18 doi: 10.1002/jnr.24740. PMID: 33070400
Clinical Characteristics and Surgical Features of Intracranial Fibrosarcoma.
Kang P, Li PL, Peng JY, Ni M, Jia GJ, Jia W
J Craniofac Surg 2020 May/Jun;31(3):825-828. doi: 10.1097/SCS.0000000000006224. PMID: 32049915
Clinical outcome of prenatally suspected cardiac rhabdomyomas of the fetus.
Altmann J, Kiver V, Henrich W, Weichert A
J Perinat Med 2019 Dec 18;48(1):74-81. doi: 10.1515/jpm-2019-0246. PMID: 31811808
Benign Glandular Schwannoma in Basal Ganglia.
Li X, Kaur H, Xu W, Wang X
World Neurosurg 2017 Jan;97:762.e1-762.e4. Epub 2016 Sep 28 doi: 10.1016/j.wneu.2016.09.073. PMID: 27686507

Recent systematic reviews

Awake brain mapping paradigms for nondominant hemisphere gliomas.
Ekert JO, Sabsevitz DS, Martin Del Campo I, Goyal A, Gillespie CS, Middlebrooks EH, Chaichana KL, Lee KS, Sanchez-Garavito JE, Quiñones-Hinojosa A
Neurosurg Focus 2024 Feb;56(2):E7. doi: 10.3171/2023.11.FOCUS23610. PMID: 38301243
Microsurgical resection of gliomas of the cingulate gyrus: a systematic review and meta-analysis.
Diaz S, Reyns N, Özduman K, Levivier M, Schulder M, Tuleasca C
Neurosurg Rev 2023 Sep 1;46(1):217. doi: 10.1007/s10143-023-02127-9. PMID: 37656287Free PMC Article
Understanding the Pathophysiology of Psychological Distress and Pancreatic Cancer: A Systematic Review.
Bettison TM, Nahm CB, Gill AJ, Mittal A, Malhi GS, Samra JS
Pancreas 2018 Apr;47(4):376-381. doi: 10.1097/MPA.0000000000001016. PMID: 29521940
Optical coherence tomography impacts the evaluation of visual pathway tumors.
Banc A, Stan C, Florian IS
Neurosurg Rev 2018 Apr;41(2):415-426. Epub 2016 Jul 28 doi: 10.1007/s10143-016-0772-1. PMID: 27465394
Treatment of pediatric cerebral radiation necrosis: a systematic review.
Drezner N, Hardy KK, Wells E, Vezina G, Ho CY, Packer RJ, Hwang EI
J Neurooncol 2016 Oct;130(1):141-148. Epub 2016 Jul 20 doi: 10.1007/s11060-016-2219-5. PMID: 27438082

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