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Epstein-Barr virus-associated mesenchymal tumor

MedGen UID:
1843096
•Concept ID:
C5679941
•
Neoplastic Process
Synonyms: EBV-associated mesenchymal tumor; EBV-associated mesenchymal tumour; Epstein-Barr Virus-associated mesenchymal tumor
 
Monarch Initiative: MONDO:0017345
Orphanet: ORPHA289656

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpstein-Barr virus-associated mesenchymal tumor

Professional guidelines

PubMed

EBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical management.
Ok CY, Li L, Young KH
Exp Mol Med 2015 Jan 23;47(1):e132. doi: 10.1038/emm.2014.82. PMID: 25613729Free PMC Article

Recent clinical studies

Etiology

Viruses in colorectal cancer.
Marongiu L, Allgayer H
Mol Oncol 2022 Apr;16(7):1423-1450. Epub 2021 Sep 30 doi: 10.1002/1878-0261.13100. PMID: 34514694Free PMC Article
Epstein-Barr virus (EBV) encoded microRNA BART8-3p drives radioresistance-associated metastasis in nasopharyngeal carcinoma.
Zhou X, Lin Y, Chen Y, Wang L, Peng X, Liao J, Zeng H, Luo W, Wu D, Cai L
J Cell Physiol 2021 Sep;236(9):6457-6471. Epub 2021 Mar 10 doi: 10.1002/jcp.30320. PMID: 33694159
Epstein-Barr Virus-Associated Post-transplant Lymphoproliferative Disease.
Ambinder RF
Recent Results Cancer Res 2021;217:197-207. doi: 10.1007/978-3-030-57362-1_9. PMID: 33200367
A review of the cytomorphology of Epstein-Barr virus-associated malignancies.
Michelow P, Wright C, Pantanowitz L
Acta Cytol 2012;56(1):1-14. Epub 2012 Jan 4 doi: 10.1159/000334235. PMID: 22236740
Epstein-Barr virus-associated epithelial and mesenchymal neoplasms.
Deyrup AT
Hum Pathol 2008 Apr;39(4):473-83. doi: 10.1016/j.humpath.2007.10.030. PMID: 18342658

Diagnosis

Epstein-Barr virus microRNA miR-BART2-5p accelerates nasopharyngeal carcinoma metastasis by suppressing RNase Ⅲ endonuclease DICER1.
Wu Y, Zhang X, Liu C, Li Z, Wen Y, Zheng R, Xu C, Tian J, Wei L, Wang J, Yan Q, Zheng X, Ma J
J Biol Chem 2023 Sep;299(9):105082. Epub 2023 Jul 24 doi: 10.1016/j.jbc.2023.105082. PMID: 37495108Free PMC Article
Follicular dendritic cell sarcoma.
Facchetti F, Simbeni M, Lorenzi L
Pathologica 2021 Oct;113(5):316-329. doi: 10.32074/1591-951X-331. PMID: 34837090Free PMC Article
Epstein-Barr Virus-Associated Post-transplant Lymphoproliferative Disease.
Ambinder RF
Recent Results Cancer Res 2021;217:197-207. doi: 10.1007/978-3-030-57362-1_9. PMID: 33200367
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
A review of the cytomorphology of Epstein-Barr virus-associated malignancies.
Michelow P, Wright C, Pantanowitz L
Acta Cytol 2012;56(1):1-14. Epub 2012 Jan 4 doi: 10.1159/000334235. PMID: 22236740

Therapy

Role of surgery in treating epstein-barr virus-associated smooth muscle tumor (EBV-SMT) with central nervous system invasion: A systemic review from 1997 to 2019.
Lau KW, Hsu YW, Lin YT, Chen KT
Cancer Med 2021 Mar;10(5):1473-1484. Epub 2021 Feb 11 doi: 10.1002/cam4.3770. PMID: 33576167Free PMC Article
Dexamethasone prevents the Epstein-Barr virus induced epithelial-mesenchymal transition in A549 cells.
Zhang F, Chen L, Zhou Y, Ding D, Hu Q, Liu Y, Li K, Wu S, He L, Lei M, Du R
J Med Virol 2020 Dec;92(12):3697-3708. Epub 2020 Jun 5 doi: 10.1002/jmv.25999. PMID: 32396272
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
Fisetin inhibits migration, invasion and epithelial-mesenchymal transition of LMP1-positive nasopharyngeal carcinoma cells.
Li R, Zhao Y, Chen J, Shao S, Zhang X
Mol Med Rep 2014 Feb;9(2):413-8. Epub 2013 Dec 2 doi: 10.3892/mmr.2013.1836. PMID: 24297333
Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients.
Deyrup AT, Lee VK, Hill CE, Cheuk W, Toh HC, Kesavan S, Chan EW, Weiss SW
Am J Surg Pathol 2006 Jan;30(1):75-82. doi: 10.1097/01.pas.0000178088.69394.7b. PMID: 16330945

Prognosis

Epstein-Barr virus microRNA miR-BART2-5p accelerates nasopharyngeal carcinoma metastasis by suppressing RNase Ⅲ endonuclease DICER1.
Wu Y, Zhang X, Liu C, Li Z, Wen Y, Zheng R, Xu C, Tian J, Wei L, Wang J, Yan Q, Zheng X, Ma J
J Biol Chem 2023 Sep;299(9):105082. Epub 2023 Jul 24 doi: 10.1016/j.jbc.2023.105082. PMID: 37495108Free PMC Article
Epstein-Barr virus-encoded microRNA BART22 serves as novel biomarkers and drives malignant transformation of nasopharyngeal carcinoma.
Zhang T, Chen Z, Deng J, Xu K, Che D, Lin J, Jiang P, Gu X, Xu B
Cell Death Dis 2022 Jul 30;13(7):664. doi: 10.1038/s41419-022-05107-x. PMID: 35907914Free PMC Article
Epstein-Barr virus (EBV) encoded microRNA BART8-3p drives radioresistance-associated metastasis in nasopharyngeal carcinoma.
Zhou X, Lin Y, Chen Y, Wang L, Peng X, Liao J, Zeng H, Luo W, Wu D, Cai L
J Cell Physiol 2021 Sep;236(9):6457-6471. Epub 2021 Mar 10 doi: 10.1002/jcp.30320. PMID: 33694159
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
Epstein-Barr virus (EBV)-associated lymphoid proliferations, a 2018 update.
Rezk SA, Zhao X, Weiss LM
Hum Pathol 2018 Sep;79:18-41. Epub 2018 Jun 6 doi: 10.1016/j.humpath.2018.05.020. PMID: 29885408

Clinical prediction guides

Epstein-Barr virus-encoded microRNA BART22 serves as novel biomarkers and drives malignant transformation of nasopharyngeal carcinoma.
Zhang T, Chen Z, Deng J, Xu K, Che D, Lin J, Jiang P, Gu X, Xu B
Cell Death Dis 2022 Jul 30;13(7):664. doi: 10.1038/s41419-022-05107-x. PMID: 35907914Free PMC Article
Epstein-Barr virus (EBV) encoded microRNA BART8-3p drives radioresistance-associated metastasis in nasopharyngeal carcinoma.
Zhou X, Lin Y, Chen Y, Wang L, Peng X, Liao J, Zeng H, Luo W, Wu D, Cai L
J Cell Physiol 2021 Sep;236(9):6457-6471. Epub 2021 Mar 10 doi: 10.1002/jcp.30320. PMID: 33694159
Epstein-Barr virus-encoded miR-BART11 promotes tumor-associated macrophage-induced epithelial-mesenchymal transition via targeting FOXP1 in gastric cancer.
Song Y, Li Q, Liao S, Zhong K, Jin Y, Zeng T
Virology 2020 Sep;548:6-16. Epub 2020 Jun 2 doi: 10.1016/j.virol.2020.05.011. PMID: 32530809
Concomitant Epstein-Barr Virus-associated smooth muscle tumor and granulomatous inflammation of the liver.
Can NT, Grenert JP, Vohra P
Pathol Res Pract 2017 Oct;213(10):1306-1309. Epub 2017 Jul 13 doi: 10.1016/j.prp.2017.07.008. PMID: 28756985
Epstein-Barr virus negative primary hepatic leiomyoma: case report and literature review.
Luo XZ, Ming CS, Chen XP, Gong NQ
World J Gastroenterol 2013 Jul 7;19(25):4094-8. doi: 10.3748/wjg.v19.i25.4094. PMID: 23840159Free PMC Article

Recent systematic reviews

Role of surgery in treating epstein-barr virus-associated smooth muscle tumor (EBV-SMT) with central nervous system invasion: A systemic review from 1997 to 2019.
Lau KW, Hsu YW, Lin YT, Chen KT
Cancer Med 2021 Mar;10(5):1473-1484. Epub 2021 Feb 11 doi: 10.1002/cam4.3770. PMID: 33576167Free PMC Article

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