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Thyroid Gland Leiomyosarcoma

MedGen UID:
1654933
•Concept ID:
C4744760
•
Neoplastic Process

Definition

A leiomyosarcoma that arises from the thyroid gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid Gland Leiomyosarcoma

Professional guidelines

PubMed

Amplitude-modulated electromagnetic fields for the treatment of cancer: discovery of tumor-specific frequencies and assessment of a novel therapeutic approach.
Barbault A, Costa FP, Bottger B, Munden RF, Bomholt F, Kuster N, Pasche B
J Exp Clin Cancer Res 2009 Apr 14;28(1):51. doi: 10.1186/1756-9966-28-51. PMID: 19366446Free PMC Article
The preoperative diagnosis of primary hyperparathyroidism by selective venous catheterization of neck veins in patients with known malignant disease.
Heath DA, Shimkin PM, Wolfe DR
J Clin Endocrinol Metab 1974 Apr;38(4):618-21. doi: 10.1210/jcem-38-4-618. PMID: 4820662

Recent clinical studies

Etiology

A rare primary leiomyosarcoma of the parotid gland: A case report and literature review.
Yue LE, Qazi M, Kiplagat K, Baik FM, Khorsandi A, Brandwein-Weber M, Urken M
Am J Otolaryngol 2018 May-Jun;39(3):345-348. Epub 2018 Feb 1 doi: 10.1016/j.amjoto.2018.01.010. PMID: 29395283
Second primary malignancies among patients with soft tissue tumors in Sweden.
Ji J, Hemminki K
Int J Cancer 2006 Aug 15;119(4):909-14. doi: 10.1002/ijc.21910. PMID: 16557572
Metastatic uterine leiomyosarcoma coexisting with papillary carcinoma of the thyroid gland.
Giannikaki E, Mantadakis E, Mamalaki E, Delides G, Samonis G
Int J Gynecol Cancer 2006 Jan-Feb;16(1):442-5. doi: 10.1111/j.1525-1438.2006.00201.x. PMID: 16445675
Clinically significant, isolated metastatic disease to the thyroid gland.
Chen H, Nicol TL, Udelsman R
World J Surg 1999 Feb;23(2):177-80; discussion 181. doi: 10.1007/pl00013162. PMID: 9880428
Cardiac lymphatic involvement by metastatic tumor.
Kline IK
Cancer 1972 Mar;29(3):799-808. doi: 10.1002/1097-0142(197203)29:3<799::aid-cncr2820290338>3.0.co;2-j. PMID: 4501215

Diagnosis

Expanding the Spectrum of NR4A3 Fusion-Positive Gynecologic Leiomyosarcomas.
Momeni-Boroujeni A, Mullaney K, DiNapoli SE, Leitao MM Jr, Hensley ML, Katabi N, Allison DHR, Park KJ, Antonescu CR, Chiang S
Mod Pathol 2024 May;37(5):100474. Epub 2024 Mar 18 doi: 10.1016/j.modpat.2024.100474. PMID: 38508521
Primary leiomyosarcoma of the thyroid gland.
Kaur M, Chatterjee D, Aggarwal P, Saini V
Indian J Pathol Microbiol 2022 Jan-Mar;65(1):142-144. doi: 10.4103/IJPM.IJPM_1380_20. PMID: 35074980
Thyroid metastasis of vaginal leiomyosarcoma: a case report and review of the literature.
Golovko A, Kuryk O *, Tkachenko R, Mendel N
Exp Oncol 2020 Sep;42(3):242-244. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-3.15029. PMID: 32996738
Thyroid leiomyosarcoma: presentation of two cases and review of the literature.
Şahin Mİ, Vural A, Yüce İ, Çağlı S, Deniz K, Güney E
Braz J Otorhinolaryngol 2016 Nov-Dec;82(6):715-721. Epub 2016 Mar 29 doi: 10.1016/j.bjorl.2015.11.020. PMID: 27080750Free PMC Article
Metastases to the thyroid gland: diagnosis by aspiration cytology.
Michelow PM, Leiman G
Diagn Cytopathol 1995 Oct;13(3):209-13. doi: 10.1002/dc.2840130306. PMID: 8575279

Therapy

Amplitude-modulated electromagnetic fields for the treatment of cancer: discovery of tumor-specific frequencies and assessment of a novel therapeutic approach.
Barbault A, Costa FP, Bottger B, Munden RF, Bomholt F, Kuster N, Pasche B
J Exp Clin Cancer Res 2009 Apr 14;28(1):51. doi: 10.1186/1756-9966-28-51. PMID: 19366446Free PMC Article
Treatment of solid tumors following allogeneic bone marrow transplantation.
Favre-Schmuziger G, Hofer S, Passweg J, Tichelli A, Hoffmann T, Speck B, Herrmann R, Gratwohl A
Bone Marrow Transplant 2000 Apr;25(8):895-8. doi: 10.1038/sj.bmt.1702339. PMID: 10808212
Laryngeal malignancy following iodine-125 therapy for thyrotoxicosis.
McKillop JH, Doig JA, Kennedy JS, Thomson JA, Greig WR
Lancet 1978 Dec 2;2(8101):1177-9. doi: 10.1016/s0140-6736(78)92158-x. PMID: 82143

Prognosis

Primary leiomyosarcoma of the thyroid gland.
Kaur M, Chatterjee D, Aggarwal P, Saini V
Indian J Pathol Microbiol 2022 Jan-Mar;65(1):142-144. doi: 10.4103/IJPM.IJPM_1380_20. PMID: 35074980
Thyroid metastasis of vaginal leiomyosarcoma: a case report and review of the literature.
Golovko A, Kuryk O *, Tkachenko R, Mendel N
Exp Oncol 2020 Sep;42(3):242-244. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-3.15029. PMID: 32996738
A rare primary leiomyosarcoma of the parotid gland: A case report and literature review.
Yue LE, Qazi M, Kiplagat K, Baik FM, Khorsandi A, Brandwein-Weber M, Urken M
Am J Otolaryngol 2018 May-Jun;39(3):345-348. Epub 2018 Feb 1 doi: 10.1016/j.amjoto.2018.01.010. PMID: 29395283
Distant Metastases in Uterine Leiomyosarcomas: The Wide Variety of Body Sites and Time Intervals to Metastatic Relapse.
Bartosch C, Afonso M, Pires-Luís AS, Galaghar A, Guimarães M, Antunes L, Lopes JM
Int J Gynecol Pathol 2017 Jan;36(1):31-41. doi: 10.1097/PGP.0000000000000284. PMID: 27015437
Thyroid leiomyosarcoma: presentation of two cases and review of the literature.
Şahin Mİ, Vural A, Yüce İ, Çağlı S, Deniz K, Güney E
Braz J Otorhinolaryngol 2016 Nov-Dec;82(6):715-721. Epub 2016 Mar 29 doi: 10.1016/j.bjorl.2015.11.020. PMID: 27080750Free PMC Article

Clinical prediction guides

Expanding the Spectrum of NR4A3 Fusion-Positive Gynecologic Leiomyosarcomas.
Momeni-Boroujeni A, Mullaney K, DiNapoli SE, Leitao MM Jr, Hensley ML, Katabi N, Allison DHR, Park KJ, Antonescu CR, Chiang S
Mod Pathol 2024 May;37(5):100474. Epub 2024 Mar 18 doi: 10.1016/j.modpat.2024.100474. PMID: 38508521
A rare primary tumor of the thyroid gland: report a new case of leiomyosarcoma and literature review.
Amal B, El Fatemi H, Souaf I, Moumna K, Affaf A
Diagn Pathol 2013 Feb 27;8:36. doi: 10.1186/1746-1596-8-36. PMID: 23445571Free PMC Article
Expression of PAX8 in normal and neoplastic tissues: a comprehensive immunohistochemical study.
Tacha D, Zhou D, Cheng L
Appl Immunohistochem Mol Morphol 2011 Jul;19(4):293-9. doi: 10.1097/PAI.0b013e3182025f66. PMID: 21285870
Treatment of solid tumors following allogeneic bone marrow transplantation.
Favre-Schmuziger G, Hofer S, Passweg J, Tichelli A, Hoffmann T, Speck B, Herrmann R, Gratwohl A
Bone Marrow Transplant 2000 Apr;25(8):895-8. doi: 10.1038/sj.bmt.1702339. PMID: 10808212
Diagnostic significance of coexpression of intermediate filaments in fine needle aspirates of human tumors.
Domagala W, Weber K, Osborn M
Acta Cytol 1988 Jan-Feb;32(1):49-59. PMID: 2447723

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