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Unresectable Colorectal Adenocarcinoma

MedGen UID:
1747614
Concept ID:
C5419194
Neoplastic Process

Definition

Colorectal adenocarcinoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, Aasi SZ, Aung PP, Barker CA, Bolotin D, Bordeaux JS, Cartee TV, Chandra S, Cho NL, Choi JN, Chung KY, Cliby WA, Dorigo O, Eisen DB, Fujisawa Y, Golda N, Halfdanarson TR, Iavazzo C, Jiang SIB, Kanitakis J, Khan A, Kim JYS, Kuzel TM, Lawrence N, Leitao MM Jr, MacLean AB, Maher IA, Mittal BB, Nehal KS, Ozog DM, Pettaway CA, Ross JS, Rossi AM, Servaes S, Solomon MJ, Thomas VD, Tolia M, Voelzke BB, Waldman A, Wong MK, Zhou Y, Arai N, Brackett A, Ibrahim SA, Kang BY, Poon E, Alam M
JAMA Oncol 2022 Apr 1;8(4):618-628. doi: 10.1001/jamaoncol.2021.7148. PMID: 35050310
Karanicolas P, Beecroft JR, Cosby R, David E, Kalyvas M, Kennedy E, Sapisochin G, Wong R, Zbuk K; Gastrointestinal Disease Site Group
Clin Colorectal Cancer 2021 Mar;20(1):20-28. Epub 2020 Oct 12 doi: 10.1016/j.clcc.2020.09.008. PMID: 33257278
Coldwell D, Sangro B, Salem R, Wasan H, Kennedy A
Am J Clin Oncol 2012 Apr;35(2):167-77. doi: 10.1097/COC.0b013e3181f47923. PMID: 21127414

Recent clinical studies

Etiology

Liao SW, Zhan JQ, Liu CT, Yu HT, Wen MJ
Am J Clin Oncol 2024 Jan 1;47(1):30-39. Epub 2023 Oct 17 doi: 10.1097/COC.0000000000001055. PMID: 38148710Free PMC Article
Xu RH, Muro K, Morita S, Iwasa S, Han SW, Wang W, Kotaka M, Nakamura M, Ahn JB, Deng YH, Kato T, Cho SH, Ba Y, Matsuoka H, Lee KW, Zhang T, Yamada Y, Sakamoto J, Park YS, Kim TW
Lancet Oncol 2018 May;19(5):660-671. Epub 2018 Mar 16 doi: 10.1016/S1470-2045(18)30140-2. PMID: 29555258
Mochizuki S, Yoshino T, Kojima T, Fuse N, Ikematsu H, Minashi K, Yano T, Tahara M, Kaneko K, Doi T, Koike K, Ohtsu A
Jpn J Clin Oncol 2010 Oct;40(10):933-7. Epub 2010 May 21 doi: 10.1093/jjco/hyq058. PMID: 20494948
Cartwright T, Kuefler P, Cohn A, Hyman W, Berger M, Richards D, Vukelja S, Nugent JE, Ruxer RL Jr, Boehm KA, Asmar L
Clin Colorectal Cancer 2008 Nov;7(6):390-7. doi: 10.3816/CCC.2008.n.052. PMID: 19036692
Lelli G, Carandina I, Urbini B, Guarino S, Modonesi C, Pedriali M
J Chemother 2007 Oct;19(5):590-5. doi: 10.1179/joc.2007.19.5.590. PMID: 18073160

Diagnosis

Mochizuki S, Yoshino T, Kojima T, Fuse N, Ikematsu H, Minashi K, Yano T, Tahara M, Kaneko K, Doi T, Koike K, Ohtsu A
Jpn J Clin Oncol 2010 Oct;40(10):933-7. Epub 2010 May 21 doi: 10.1093/jjco/hyq058. PMID: 20494948
Lelli G, Carandina I, Urbini B, Guarino S, Modonesi C, Pedriali M
J Chemother 2007 Oct;19(5):590-5. doi: 10.1179/joc.2007.19.5.590. PMID: 18073160

Therapy

Xu RH, Muro K, Morita S, Iwasa S, Han SW, Wang W, Kotaka M, Nakamura M, Ahn JB, Deng YH, Kato T, Cho SH, Ba Y, Matsuoka H, Lee KW, Zhang T, Yamada Y, Sakamoto J, Park YS, Kim TW
Lancet Oncol 2018 May;19(5):660-671. Epub 2018 Mar 16 doi: 10.1016/S1470-2045(18)30140-2. PMID: 29555258
Mochizuki S, Yoshino T, Kojima T, Fuse N, Ikematsu H, Minashi K, Yano T, Tahara M, Kaneko K, Doi T, Koike K, Ohtsu A
Jpn J Clin Oncol 2010 Oct;40(10):933-7. Epub 2010 May 21 doi: 10.1093/jjco/hyq058. PMID: 20494948
Cartwright T, Kuefler P, Cohn A, Hyman W, Berger M, Richards D, Vukelja S, Nugent JE, Ruxer RL Jr, Boehm KA, Asmar L
Clin Colorectal Cancer 2008 Nov;7(6):390-7. doi: 10.3816/CCC.2008.n.052. PMID: 19036692
Lelli G, Carandina I, Urbini B, Guarino S, Modonesi C, Pedriali M
J Chemother 2007 Oct;19(5):590-5. doi: 10.1179/joc.2007.19.5.590. PMID: 18073160
Kim TW, Kang WK, Chang HM, Park JO, Ryoo BY, Ahn JS, Zang DY, Lee KH, Kang YK, Kim SR, Kim HK; Korean Cancer Study Group
Acta Oncol 2005;44(3):230-5. doi: 10.1080/02841860510029590. PMID: 16076694

Prognosis

Liao SW, Zhan JQ, Liu CT, Yu HT, Wen MJ
Am J Clin Oncol 2024 Jan 1;47(1):30-39. Epub 2023 Oct 17 doi: 10.1097/COC.0000000000001055. PMID: 38148710Free PMC Article
Mochizuki S, Yoshino T, Kojima T, Fuse N, Ikematsu H, Minashi K, Yano T, Tahara M, Kaneko K, Doi T, Koike K, Ohtsu A
Jpn J Clin Oncol 2010 Oct;40(10):933-7. Epub 2010 May 21 doi: 10.1093/jjco/hyq058. PMID: 20494948
Lelli G, Carandina I, Urbini B, Guarino S, Modonesi C, Pedriali M
J Chemother 2007 Oct;19(5):590-5. doi: 10.1179/joc.2007.19.5.590. PMID: 18073160
Kim TW, Kang WK, Chang HM, Park JO, Ryoo BY, Ahn JS, Zang DY, Lee KH, Kang YK, Kim SR, Kim HK; Korean Cancer Study Group
Acta Oncol 2005;44(3):230-5. doi: 10.1080/02841860510029590. PMID: 16076694

Clinical prediction guides

Liao SW, Zhan JQ, Liu CT, Yu HT, Wen MJ
Am J Clin Oncol 2024 Jan 1;47(1):30-39. Epub 2023 Oct 17 doi: 10.1097/COC.0000000000001055. PMID: 38148710Free PMC Article
Xu RH, Muro K, Morita S, Iwasa S, Han SW, Wang W, Kotaka M, Nakamura M, Ahn JB, Deng YH, Kato T, Cho SH, Ba Y, Matsuoka H, Lee KW, Zhang T, Yamada Y, Sakamoto J, Park YS, Kim TW
Lancet Oncol 2018 May;19(5):660-671. Epub 2018 Mar 16 doi: 10.1016/S1470-2045(18)30140-2. PMID: 29555258
Mochizuki S, Yoshino T, Kojima T, Fuse N, Ikematsu H, Minashi K, Yano T, Tahara M, Kaneko K, Doi T, Koike K, Ohtsu A
Jpn J Clin Oncol 2010 Oct;40(10):933-7. Epub 2010 May 21 doi: 10.1093/jjco/hyq058. PMID: 20494948

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