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| Status |
Public on Jun 22, 2016 |
| Title |
Global re-wiring of p53 transcription regulation by the hepatitis B virus X (HBx) protein [Agilent] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
As HBx has been reported to interact with p53 and alter the recruitment of p53 to its binding sites, we would like to identify p53-associated genes that were deregulated by HBx. We employed whole genome microarray expression profiling to identify genes that were deregulated by HBx protein.
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| Overall design |
HepG2 cells were transduced with recombinant HBx and control adenoviruses 24 hours post seeding. HepG2 cells were treated with UVC (254 nm) irradiation 48 hours postransduction and harvested 24 hours after UV irradiation. Experiements were conducted with three biological replicates.
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| |
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| Contributor(s) |
Chan C, Thurnherr T, Lee C |
| Citation(s) |
27302019 |
| |
| Submission date |
Jan 12, 2015 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Thomas Thurnherr |
| E-mail(s) |
thomas.thurnherr@gmail.com
|
| Organization name |
NCCS
|
| Lab |
LCFG
|
| Street address |
11 Hospital Drive
|
| City |
Singapore |
| ZIP/Postal code |
169610 |
| Country |
Singapore |
| |
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| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE64878 |
Global re-wiring of p53 transcription regulation by the hepatitis B virus X (HBx) protein |
|
| Relations |
| BioProject |
PRJNA272432 |
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