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Series GSE133577 Query DataSets for GSE133577
Status Public on Aug 05, 2020
Title Effects of entero-gastro-anastomosis (EGA) surgery in ob/ob mice on pancreatic islet gene expression
Organism Mus musculus
Experiment type Expression profiling by array
Summary Bariatric surgical techniques are known to cause weight loss and diabetes remission to varying degrees in severly obese patients. However, the mechanisms involved in the restoration of beta-cell function remain to be uncovered. In this study, the leptin-deficient ob/ob mouse was used as a model to investigate the effect of EGA bariactric surgery on pancreatic islet gene expression.
Overall design At 3 months of age, C57Bl6-ob/ob mice were randomized to EGA or sham surgery. Pancreatic islets were isolated 28 days after the surgery. C57Bl/6J mouse islets were used as lean/non-obese control.
Contributor(s) Amouyal C, Guay C, Regazzi R, Magnan C, Andreelli F
Citation(s) 32739864
Submission date Jul 01, 2019
Last update date Aug 05, 2020
Contact name Claudiane Guay
Phone +41216925281
Organization name University of Lausanne
Department DNF
Street address Du Bugnon 9
City Lausanne
State/province Vaud
ZIP/Postal code 1005
Country Switzerland
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (12)
GSM3912461 WT1
GSM3912462 WT2
GSM3912463 WT3
This SubSeries is part of SuperSeries:
GSE133852 ob/ob mice on pancreatic islet
BioProject PRJNA552806

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE133577_RAW.tar 25.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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