GEO DataSets

(Submitter supplied) Deoxynivalenol (DON) is a type B trichothecene mycotoxin that is commonly found in cereals and grains worldwide. The presence of this fungal secondary-metabolite raises public-health concerns at both the agriculture and food industry level. The toxicity of DON is mainly characterized by its ability to inhibit ribosomal protein biosynthesis. Recently, we have shown that DON has a negative impact on gut integrity, a feature also noticed for Campylobacter (C.) jejuni. more...

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26884

20 Samples

Download data: XLSX

(Submitter supplied) Three translatomic approaches were applied to the foodborne pathogen Campylobacter jejuni to identify translated open reading frames, start codons, and stop codons and reveal novel small proteins

Organism:

Campylobacter jejuni

Type:

Other; Expression profiling by high throughput sequencing

Platform:

GPL26884

30 Samples

Download data: BW, GFF

(Submitter supplied) Termination site sequencing (term-seq) (Dar et al., 2016) was used to map transcript 3' ends and potential processing sites in Campylobacter jejuni NCTC11168 wildtype and ribonuclease deletion strains.

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26884

10 Samples

Download data: WIG

(Submitter supplied) differential RNA sequencing (dRNA-seq) (Sharma et al., 2010; Dugar et al., 2013) was used to differentially map 5' ends in Campylobacter jejuni NCTC11168 wildtype and RNase III (rnc, Cj1635c) deletion.

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17549

4 Samples

Download data: WIG

(Submitter supplied) RNA-seq was used to study gene expression profiles and potential processing sites in Campylobacter jejuni NCTC11168 wildtype and RNase Y (rny, Cj1209) deletion.

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26884

6 Samples

Download data: WIG

(Submitter supplied) Polyamines, crucial molecules involved in cell proliferation and growth, play a pivotal role in cancer development and progression. Within the tumor microenvironment, macrophages, key components of the immune system, exhibit a complex relationship with polyamines. Evidence suggests that polyamines can modulate macrophage polarization, influencing their functional phenotypes. Here, we detected the gene DNA methylation changes in spermine-stimulated human macrophages isolated from PBMCs and TAMs.

Organism:

Leptospira interrogans; Rickettsia typhi; Mycobacterium tuberculosis variant bovis; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant microti; Mycobacterium canetti; Orthohantavirus seoulense; Yersinia enterocolitica; Toxoplasma gondii; Salmonella enterica subsp. enterica serovar Typhimurium; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Campylobacter jejuni; Francisella tularensis subsp. novicida; Yersinia pestis; Staphylococcus aureus; Mycobacterium avium subsp. paratuberculosis; Cowpox virus; Escherichia coli O157:H7; Francisella tularensis subsp. mediasiatica; Paslahepevirus balayani; Yersinia pseudotuberculosis; Rickettsia prowazekii; Bartonella quintana; Mycobacterium avium; Homo sapiens; Streptobacillus moniliformis; Bartonella henselae; Francisella tularensis subsp. tularensis; Francisella tularensis subsp. holarctica

Type:

Methylation profiling by array

Platform:

GPL21445

4 Samples

Download data: IDAT, TXT

(Submitter supplied) To investigate the interaction of intra-amoebal C. jejuni with the transient host A. castellanii. We then performed gene expression profiling analysis using data obtained from RNA-seq of control and intra-amoebal C. jejuni.

Organism:

Campylobacter jejuni; Acanthamoeba castellanii

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL28665 GPL32395

6 Samples

Download data: TXT

(Submitter supplied) Methods: RNA-Seq was used to identify differentially expressed genes between wild type strains, ∆rrpA and ∆rrpB mutants at mid-log (~6 hrs) of growth. 11168H wild type, 11168H∆rrpA, 11168H∆rrpB and 11168H∆rrpAB were plated out on BA plates and incubated at 37°C under microaerobic conditions for 6 hrs. RNA was extracted from the pelleted bacteria cells using PureLink™ RNA Mini Kit (Invitrogen), following manufactures protocol. more...

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22824

20 Samples

Download data: CSV, TSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Campylobacter jejuni subsp. jejuni CG8421

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL29024 GPL29023

10 Samples

Download data: WIG

(Submitter supplied) Differential RNA sequencing using terminator exonuclease (TEX) to identify processed versus unprocessed transcripts in Campylobacter jejuni strain CG84-21

Organism:

Campylobacter jejuni subsp. jejuni CG8421

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29024

4 Samples

Download data: WIG

(Submitter supplied) RIP-seq analysis to identify CjCas9 bound RNAs using co-immunoprecipitation and sequencing in CG84-21.

Organism:

Campylobacter jejuni subsp. jejuni CG8421

Type:

Other

Platform:

GPL29023

6 Samples

Download data: WIG

(Submitter supplied) Pathogenic bacteria encounter a variety of stressful host environments during infection. Their responses to meet these challenges protect them from deadly damages and aid in adaption to harmful environments. Bacterial products critical for this protection are therefore interesting as suitable targets for new antimicrobials. To shed light on the complex array of molecular pathways involved in bacterial stress responses we challenged 32 diverse human pathogenic bacteria to 11 infection related stress conditions and catalogued their transcriptomes. more...

Organism:

Neisseria meningitidis; Staphylococcus epidermidis; Streptococcus pyogenes; Listeria monocytogenes; Salmonella enterica; Achromobacter xylosoxidans; Campylobacter jejuni; Francisella tularensis; Acinetobacter baumannii; Neisseria gonorrhoeae; Escherichia coli; Shigella flexneri; Aggregatibacter actinomycetemcomitans; Haemophilus influenzae; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Borreliella burgdorferi; Pseudomonas aeruginosa; Legionella pneumophila; Klebsiella pneumoniae; Yersinia pseudotuberculosis; Vibrio cholerae; Streptococcus suis; Streptococcus agalactiae; Streptococcus pneumoniae; Mycobacterium tuberculosis; Burkholderia pseudomallei; Helicobacter pylori; Enterococcus faecalis

Type:

Expression profiling by high throughput sequencing

30 related Platforms

1122 Samples

Download data: TXT

(Submitter supplied) Growth of Campylobacter jejuni in butyrate, including deletions of a TCS involved in sensing this response

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27965

18 Samples

Download data: XLSX

(Submitter supplied) The symptoms of infectious diarrheal disease are mediated by the interplay between the host and pathogen. Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide due to its near-ubiquitous zoonotic association with poultry. One of the outstanding questions is what factors drive the intestinal inflammation during the development of C. jejuni-mediated disease. Specifically, it is not known the extent to which the bacteria are responsible for the diarrheal symptoms via cell necrosis, or whether there is immune cell recruitment prior to tissue damage. more...

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22824

78 Samples

Download data: CSV

(Submitter supplied) Biofilms serve as a protective mechanism for bacteria to cope with environmental stress. Whilst ordinarily a fastidious organism, it has been long suggested that C. jejuni is able to utilise this mode of growth as a way to transmit infection from the avian host to humans. Herein, we undertook a combinatorial approach to examine differential expression of C. jejuni genes and protein abundance during biofilm formation. more...

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26884

6 Samples

Download data: XLSX

(Submitter supplied) Major foodborne bacterial pathogens, such as Campylobacter jejuni, have devised complex strategies to establish and foster intestinal infections. For more than two decades researchers have used immortalized cell lines derived from human intestinal tissue to dissect C. jejuni-host cell interactions. Known from these studies is that C. jejuni virulence is multifactorial, requiring a coordinated response to produce virulence factors that facilitate the bacterium’s host-cell interactions. more...

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL22824 GPL25035

12 Samples

Download data: CSV

(Submitter supplied) Campylobacter jejuni produces a single flagellum on one or both poles of the cell, the polar flagella not only confer the bacterium darting motility but also involved in its virulence and metabolic processes. FlhF is a lately defined flagella biosynthesis regulator, but how it regulates flagella assembly isn’t clear at present. Previous research had indicated FlhF was associated with gene expression, to understanding its role in flagella system and its correlation with C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL22549

6 Samples

Download data: TXT

(Submitter supplied) Campylobacter jejuni is one of the most important causes of food-borne diseases in industrialized countries. It is known that amino acids are important nutrient source for this pathogen, because C. jejuni lacks enzymes related to glycolysis. However, the characteristics on metabolism of C. jejuni grown in the nutrient restricted medium with a specific amino acid is not fully elucidated. This study shows that C. more...

Organism:

Campylobacter jejuni; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL25530

2 Samples

Download data: TXT

(Submitter supplied) Filamentation, the transition from rod to filamentous cell morphology, has been identified as a response to stressful conditions in many bacterial species. Campylobacter jejuni exhibits filamentation upon entry to stationary phase. This study examines the cell mophotype specific transciptomes (RNAseq) of C. jejuni.

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19974

9 Samples

Download data: TXT

(Submitter supplied) Filamentation, the transition from rod to filamentous cell morphology, has been identified as a response to stressful conditions in many bacterial species. Campylobacter jejuni exhibits filamentation upon entry to stationary phase. This study examines the cell mophotype specific transciptomes (RNAseq) of C. jejuni.

Organism:

Campylobacter jejuni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19974

9 Samples

Download data: TXT