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Links from GEO DataSets

Items: 20

1.

Comparative transcriptomics of Aspergillus niger when deleted or overexpressed for the putative transcription factors MjkA, MjkB and the histon deactelyase HdaX

(Submitter supplied) Purpose: Expression profiling of two ORFs encoding putative transcription factors: An07g07370 (TF1/MjkA) and An12g07690 (TF2/MjkB), and a histone deacetylase (An09g06520, HdaX) under carbon-limited batch cultivations (biological duplicate runs) in Aspergillus niger. Methods: Single deletion strains for TF1, TF2 and HD, respectively, (ii) a double deletion strain for TF1 and TF2, and (iii) individual conditional overexpression mutants for TF1, TF2 and HD using the Tet-on system were analysed. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25519
28 Samples
Download data: TXT
Series
Accession:
GSE119311
ID:
200119311
2.

Aspergillus niger exposed to combinations of carbon source, nitrogen source, nitrogen concentration, and culture pH

(Submitter supplied) Microarray analysis of Aspergillus niger under conditions with differing combinations of carbon source, nitrogen source, nitrogen concentration, and culture pH Fermentor cultures were grown in minimal medium (MM) at a constant temperature of 30 ± 0.5 ºC and with differing combinations of carbon source (either 277.5 mM glucose or 333.0 mM xylose), nitrogen source (NH4Cl or NaNO3) and nitrogen concentration (4x: 282.4 mM; 8x: 564.8 mM), and pH (pH4 or pH5) of the medium (M. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
20 Samples
Download data: CEL
Series
Accession:
GSE17329
ID:
200017329
3.

The transcriptional response of bioreactor-grown Aspergillus niger cultures towards three oils

(Submitter supplied) The industrially important fungus Aspergillus niger feeds naturally on decomposing plant material, for which it is equipped with a range of enzyme systems. A significant proportion of plant material are lipids that might be available either as for energy storage or as membrane building blocks. With 63 potential lipase-encoding genes in its genome, A. niger has the tools to degrade these extracellular lipids. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
16 Samples
Download data: CEL
Series
Accession:
GSE14285
ID:
200014285
4.

Determination of variability of fermentor-grown Aspergillus niger

(Submitter supplied) Knowledge of the biological and technical variation for fermentor-grown Aspergillus niger cultures is needed to design DNA microarray experiments properly. We cultured A. niger in batch-operated fermentor vessels and induced with D-xylose. Transcript profiles were followed in detail by qPCR for 8 genes. A variance components analysis was performed on these data to determine the origin and magnitude of variation within each process step for this experiment. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
7 Samples
Download data: CEL
Series
Accession:
GSE11405
ID:
200011405
5.

In vivo functional analysis of L-rhamnose metabolic pathway in Aspergillus niger: a tool to identify the potential inducer of RhaR

(Submitter supplied) The genes of the non-phosphorylative L-rhamnose catabolic pathway have been identified for several yeast species. In Pichia stipitis, all L-rhamnose pathway genes are organized in a cluster, which is conserved in Aspergillus niger, except for the lra-4 ortholog (lraD). The A. niger cluster also contains the gene encoding the L-rhamnose responsive transcription factor (RhaR) that has been shown to control the expression of genes involved in L-rhamnose release and catabolism. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
10 Samples
Download data: TXT
Series
Accession:
GSE99865
ID:
200099865
6.

The carbon starvation response of Aspergillus niger during submerged cultivation

(Submitter supplied) Filamentous fungi are confronted with changes and limitations of their carbon source during growth in their natural habitats and during industrial applications. To survive life-threatening starvation conditions, carbon from extra- and intracellular resources becomes mobilized to fuel fungal self-propagation. Key to understand the underlying cellular processes is the system-wide analysis of fungal starvation responses in a temporal and spatial resolution. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
6 Samples
Download data: CEL
Series
Accession:
GSE39559
ID:
200039559
7.

Expression-based clustering of CAZyme-encoding genes of Aspergillus niger

(Submitter supplied) The Aspergillus niger genome contains a large repertoire of genes encoding carbohydrate active enzymes (CAZymes) that are targeted to plant polysaccharide degradation enabling A. niger to grow on a wide range of plant biomass substrates. Which genes need to be activated in certain environmental conditions depends on the composition of the available substrate. Previous studies have demonstrated the involvement of a number of transcriptional regulators in plant biomass degradation and have identified sets of target genes for each regulator. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
59 Samples
Download data: CEL
Series
Accession:
GSE98572
ID:
200098572
8.

The FlbA-regulated transcription factor FusR of Aspergillus niger is involved in production of fumonisin

(Submitter supplied) Colonies of Aspergillus niger secrete proteins throughout the colony except for the sporulating zone. Inactivation of flbA results in colonies that are unable to reproduce asexually and that secrete proteins throughout the mycelium. In addition, the ΔflbA strain shows cell lysis and has thinner cell walls. This pleiotropic phenotype is associated with differential expression of 38 transcription factor genes. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21090
4 Samples
Download data: DIFF
Series
Accession:
GSE93990
ID:
200093990
9.

Identification of three enzymes of the vanillin and vanillic acid metabolic pathway in the filamentous fungi Aspergillus niger

(Submitter supplied) The aim of this study was to find candidate genes in A. niger involved in the vanillic acid metabolic pathway.
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25519
8 Samples
Download data: TXT
Series
Accession:
GSE154865
ID:
200154865
10.

Evolutionary adaptation of Aspergillus niger for increased ferulic acid tolerance

(Submitter supplied) The aim of this study was to find candidate genes in A. niger involved in the increase tolerance against ferulic acid in A. niger Fa6
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
8 Samples
Download data: TXT
Series
Accession:
GSE135001
ID:
200135001
11.

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

(Submitter supplied) Using transcriptomics, the strain-specific metabolism was mapped for two whole-genome sequenced strains of Aspergillus niger Keywords: Strain comparison
Organism:
Aspergillus niger; Aspergillus nidulans; Aspergillus oryzae
Type:
Expression profiling by array
Platform:
GPL5975
6 Samples
Download data: CEL
Series
Accession:
GSE10983
ID:
200010983
12.

Submerged differentiation of Aspergillus niger in carbon-limited cultures approaching zero specific growth rate

(Submitter supplied) This work presents an exploration of submerged differentiation of the ubiquitous saprophyte and industrially important fungus, Aspergillus niger, in response to a limited availability of a sole carbon and energy source, maltose. In aspergilli and other mold fungi, asexual reproduction through formation of elaborate conidiogenic structures normally requires an aerial interface. This requirement is bypassed in submerged culture in response to severe nutrient limitation. more...
Organism:
Aspergillus niger CBS 513.88; Aspergillus niger
Type:
Expression profiling by array
Platform:
GPL6758
9 Samples
Download data: CEL
Series
Accession:
GSE21752
ID:
200021752
13.

The transcriptional repressor TupA in Aspergillus niger is involved in controlling gene expression related to cell wall biosynthesis, development, and nitrogen source availability

(Submitter supplied) The Tup1-Cyc8 (Ssn6) complex is a well characterized and conserved general transcriptional repressor complex in eukaryotic cells. Here, we report the identification of the Tup1 (TupA) homolog in the filamentous fungus Aspergillus niger in a genetic screen for mutants with a constitutive expression of the agsA gene. The agsA gene encodes a putative alpha-glucan synthase, which is induced in response to cell wall stress in A niger. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
4 Samples
Download data: CEL
Series
Accession:
GSE50523
ID:
200050523
14.

Transcriptome study on Aspergillus niger during citrate fermentation.

(Submitter supplied) We report the genes regulated during citrate fermentation.
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21090
6 Samples
Download data: FASTA, TXT
Series
Accession:
GSE74544
ID:
200074544
15.

Single tip transcriptomics of neighboring hyphae of Aspergillus niger

(Submitter supplied) Mycelia of filamentous fungi explore new substrates by means of hyphae that extend from the periphery of the colony. Previously, it has been shown by immuno-labelling, reporter studies and in situ hybridization that these exploring hyphae are heterogenic with respect to protein secretion and transcription. We performed single hyphal tip RNA profiling using microarrays to assess the differences in RNA accumulation in neighboring exploring hyphae
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
5 Samples
Download data: CEL
Series
Accession:
GSE25497
ID:
200025497
16.

Study of the response of Aspergillus niger to three levels of ambient pH

(Submitter supplied) The multiple modes of response to ambient pH were explored and new regulatory structures determined.
Organism:
Aspergillus oryzae; Aspergillus niger; Aspergillus nidulans
Type:
Expression profiling by array
Platform:
GPL5975
9 Samples
Download data: CEL
Series
Accession:
GSE11725
ID:
200011725
17.

The fungus Aspergillus niger consumes sugars in a sequential manner that is not mediated by the carbon catabolite repressor CreA

(Submitter supplied) Aspergillus niger is a filamentous ascomycete fungus that is commonly found in most biotopes around the globe. In nature, A. niger degrades the plant biomass polysaccharides to monomeric sugars, transports them into the cells, and uses a variety of catabolic pathways to convert them into biochemical building blocks and energy. We show that when grown in liquid cultures, A. niger takes up plant-biomass derived monomeric sugars (and maltose) in a highly sequential manner, rather than simultaneously. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
8 Samples
Download data: CEL
Series
Accession:
GSE98434
ID:
200098434
18.

The galactose regulator GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger.

(Submitter supplied) Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in D-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX does not substitute for the absence of GalR in A. niger, it regulates the D-galactose oxido-reductive pathway, but not the Leloir pathway. more...
Organism:
Aspergillus niger CBS 513.88; Aspergillus niger
Type:
Expression profiling by array
Platform:
GPL6758
4 Samples
Download data: CEL
Series
Accession:
GSE40219
ID:
200040219
19.

Conservation and divergence in the asexual development gene regulatory network across a genus of filamentous fungi

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Aspergillus nidulans; Aspergillus fumigatus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL23160 GPL20839
8 Samples
Download data: TXT
Series
Accession:
GSE114167
ID:
200114167
20.

Conservation and divergence in the asexual development gene regulatory network across a genus of filamentous fungi [RNA-seq]

(Submitter supplied) Asexual development is fundamental to the ecology and lifestyle of filamentous fungi and can facilitate both plant and human infection. In the filamentous fungal genus Aspergillus, the production of asexual spores is primarily governed by the BrlA-AbaA-WetA central regulatory cascade. The final step in this cascade, which is controlled by the WetA protein, not only governs cellular development (i.e., the morphological differentiation of spores) but also ensures its coupling with chemical development (i.e., the coordinated production and deposition of diverse secondary metabolites, such as aflatoxins, into spores). more...
Organism:
Aspergillus nidulans; Aspergillus fumigatus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20839 GPL23160
4 Samples
Download data: TXT
Series
Accession:
GSE114143
ID:
200114143
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