Similar studies for GEO DataSets (Select 200043591) - GEO DataSets

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Items: 20

Select item 2000435911.

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) mRNA

(Submitter supplied) MicroRNAs are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed global microarray analyses of mRNA and microRNA in peripheral blood T-cells from relapsing-remitting MS patients and controls. We identified 2,452 regulated genes and 21 regulated microRNA that differed between MS patients and controls. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
20 Samples

Download data: CEL

Series

Accession:: GSE43591

ID:: 200043591

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Select item 2000435922.

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL570 GPL14613
40 Samples

Download data: CEL

Series

Accession:: GSE43592

ID:: 200043592

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Select item 2000435903.

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) miRNA

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
20 Samples

Download data: CEL

Series

Accession:: GSE43590

ID:: 200043590

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Select item 2001207694.

Screening for potential target genes of microRNA-548ac using HTA 2.0 microarrays

(Submitter supplied) We screened for target genes of hsa-miR-548ac by transcriptome profiling. The miRNA was overexpressed in HeLa cells by transient transfection of a precursor miRNA expression plasmid. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis. This GEO entry provides the microarray data preprocessed according to the gene level workflow.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
10 Samples

Download data: CEL, CHP

Series

Accession:: GSE120769

ID:: 200120769

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Select item 2000143525.

Genome Wide Analysis of Immune Activation in Human T and B Cells Reveals Distinct Classes of Alternatively Spliced Genes

(Submitter supplied) Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it plays during the immune response. Our study is among the first reports of a systematic genome-wide analysis using whole exon DNA microarrays integrating alternative splicing and differential gene expression. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL5188
80 Samples

Download data: CEL

Series

Accession:: GSE14352

ID:: 200014352

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Select item 2000210796.

MicroRNA profiling of Multiple Sclerosis

(Submitter supplied) It is well established that Multiple Sclerosis (MS) is an immune mediated disease. Little is known about what drives the differential control of the immune system in MS patients compared to unaffected individuals. MicroRNAs (miRNAs) are small non-coding nucleic acids that are involved in the control of gene expression. Their potential role in T cell activation and neurodegenerative disease has recently been recognized and they are therefore excellent candidates for further studies in MS. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8178
96 Samples

Download data: TXT

Series

Accession:: GSE21079

ID:: 200021079

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Select item 2000367277.

MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Glucocorticoid Steroid Treatment and Relationship with mRNA Target Expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by RT-PCR

Platforms:: GPL13328 GPL6244
20 Samples

Download data: CEL

Series

Accession:: GSE36727

ID:: 200036727

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Select item 2000367268.

miRNA Profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the miRNA expression changes in EoE before and after a successful glucocorticoid steroid treatment.

Organism:: Homo sapiens

Type:: Expression profiling by RT-PCR

Platform:: GPL13328
10 Samples

Download data: TXT

Series

Accession:: GSE36726

ID:: 200036726

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Select item 2000367259.

Gene profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the gene expression changes in EoE before and after a successful glucocorticoid steroid treatment. We used microarrays to identify distinct genes involving the pathophysiology of EoE.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
10 Samples

Download data: CEL

Series

Accession:: GSE36725

ID:: 200036725

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Select item 20005822010.

Expression data from primary term human decidual cells treated with interleukin-1-beta for 6 hours.

(Submitter supplied) Preterm birth is an important unsolved clinical problem. Despite advanced treatments, infants who survive prematurity remain at increased risk for permanent disabilities. In approximately one-third of cases, prematurity is related to infection and/or inflammation, which renders hostile the normally receptive intrauterine environment. Proinflammatory cytokines provoke up-regulation of genes that promote uterine contractions. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE58220

ID:: 200058220

Select item 20004317911.

MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL570 GPL14613
37 Samples

Download data: CEL

Series

Accession:: GSE43179

ID:: 200043179

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Select item 20004317812.

MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP) [miRNA]

(Submitter supplied) MicroRNA are small non-coding RNA molecules that regulate gene expression. To investigate the role of microRNA in ITP, we performed genome-wide expression analyses of mRNA and microRNA in T-cells from ITP patients and controls. We identified 1,915 regulated genes and 22 regulated microRNA that differed between ITP patients and controls. Seventeen of the 22 regulated microRNA were linked to changes in target gene expression; 57 of these target genes were associated with the immune system, e.g. more...

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
18 Samples

Download data: CEL

Series

Accession:: GSE43178

ID:: 200043178

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Select item 20004317713.

MicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP) [mRNA]

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
19 Samples

Download data: CEL

Series

Accession:: GSE43177

ID:: 200043177

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Select item 20004895914.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6244
48 Samples

Download data: CEL

Series

Accession:: GSE48959

ID:: 200048959

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Select item 20004895815.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
21 Samples

Download data: CEL

Series

Accession:: GSE48958

ID:: 200048958

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Select item 20004895716.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
27 Samples

Download data: CEL

Series

Accession:: GSE48957

ID:: 200048957

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Select item 20004504117.

Transcriptome-wide microRNA expression of white blood cells before and after intense cardiorespiratory exercise

(Submitter supplied) Regular physical exercise reduces cardiovascular disease (CVD) morbidity and mortality through several biological mechanisms. We were interested in white blood cell microRNA expression in response to exercise. Ten healthy adult males (19-39 years old) undertook 30 minutes of continuous treadmill running at 80% of maximal oxygen uptake (VO2max). Blood samples were taken before and immediately after exercise. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL16770
20 Samples

Download data: TXT

Series

Accession:: GSE45041

ID:: 200045041

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Select item 20009317118.

microRNA profile in CD4+ T cell in healthy control and Primay biliary cholangitis (PBC) [miRNA]

(Submitter supplied) Primary biliary cholangitis (PBC), formally known as primary biliary cirrhosis, is an autoimmune liver disease of unknown pathogenesis. Consequently, therapeutic targets for PBC have yet to be identified. As CD4+ T cells play a pivotal role in immunological dysfunction observed in PBC, we analyzed microRNA(miRNA) and mRNA expression in CD4+ T cells to investigate PBC pathogenesis and identify novel therapeutic targets.