Similar studies for GEO DataSets (Select 200003586) - GEO DataSets

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Items: 20

Select item 2000035861.

Dilated Cardiomyopathy and Non Failing Septal Biopsies

(Submitter supplied) Dilated cardiomyopathy (DCM) is a common cause of heart failure and a leading cause of cardiac transplantation in western countries. The robust predictive expression profile of cardiomyopathic and NF hearts as well as the functional classification can help to identify promising candidates for DCM and may improve the early diagnosis of cardiomyopathy. Keywords: disease state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2206
Platform:: GPL3050
28 Samples

Download data: GPR

Series

Accession:: GSE3586

ID:: 200003586

Select item 2000035852.

Dilated Cardiomyopathy and Non Failing Biopsies

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2205
Platform:: GPL96
12 Samples

Download data: CEL, EXP

Series

Accession:: GSE3585

ID:: 200003585

Select item 22063.

Dilated cardiomyopathy: septum

Comparison of septal myocardial tissue samples from 13 patients with dilated cardiomyopathy (DCM) to those from 15 patients with non-failing (NF) hearts. DCM is a common cause of heart failure. Results contribute to the identification of a gene expression signature for DCM.

Organism:: Homo sapiens

Type:: Expression profiling by array, log2 ratio, 2 disease state sets

Platform:: GPL3050
Series:: GSE3586
28 Samples

Download data: GPR

DataSet

Accession:: GDS2206

ID:: 2206

Select item 22054.

Dilated cardiomyopathy: left ventricle

Comparison of subendocardial left ventricular tissue samples from 7 patients with dilated cardiomyopathy (DCM) to those from 5 patients with non-failing (NF) hearts. DCM is a common cause of heart failure. Results contribute to the identification of a gene expression signature for DCM.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL96
Series:: GSE3585
12 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2205

ID:: 2205

Select item 2000061405.

Cross platform microarray analysis for robust identification of differentially expressed genes

(Submitter supplied) Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternative that is complementary to RT-PCR for identification of the more robust changes in gene expression profiles. In this paper, we combined statistical and functional analysis for the cross platform validation of two oligonucleotide-based technologies, Affymetrix (AFFX) and Applied Biosystems (ABI), and for the identification of differentially expressed genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL1426 GPL570
12 Samples

Download data: CEL

Series

Accession:: GSE6140

ID:: 200006140

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000052086.

Analysis of gene expression profiling of normal retina and brain cortices

(Submitter supplied) Using a canine custom retinal cDNA microarray our aim is to identify normal gene expression profiling for retina and frontal, occipital and temporal brain cortices Keywords: retina-brain comparisons

Organism:: Canis lupus familiaris

Type:: Expression profiling by array

Platforms:: GPL3951 GPL3957
11 Samples

Download data

Series

Accession:: GSE5208

ID:: 200005208

Select item 1000097437.

UPenn_canine_retinal_EST_4.5k array

(Submitter supplied) GPL9743 represents two different print sets, v1 and v2. While the order of the clones are not exactly the same in v1 and v2, the clones themselves are identical. The Platform data table reflects a condensed representation of the print sets' replicate features. The v1 and v2 full array layout (.gal) files, representing all of the individual features, are linked below as supplementary files. Protocol: EST clones were obtained from a normalized canine retinal library cloned into pGEM 11ZF(+) vector (Promega). more...

Organism:: Canis lupus familiaris

1 Series
12 Samples

Download data: GAL

Platform

Accession:: GPL9743

ID:: 100009743

PubMed Similar studies

Select item 2000018698.

Ischemic and Nonischemic CM and NF Hearts

(Submitter supplied) Pre-LVAD and explanted ischemic and nonischemic cardiomyopathy and nonfailing hearts all normalized with RMA Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1362
Platform:: GPL96
37 Samples

Download data: CEL

Series

Accession:: GSE1869

ID:: 200001869

Select item 13629.

Ischemic and nonischemic cardiomyopathy comparison

Analysis of myocardial tissues from nonischemic (NICM) and ischemic cardiomyopathy (ICM) patients. NICM and ICM, major forms of dilated cardiomyopathy leading to congestive heart failure, have similar presentations but differ in pathophysiology, prognosis, and response to therapy.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 disease state sets

Platform:: GPL96
Series:: GSE1869
37 Samples

Download data: CEL

DataSet

Accession:: GDS1362

ID:: 1362

Select item 20000214310.

Human coronary artery study

(Submitter supplied) Study of atherosclerosis using 51 human coronary artery segments Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1597
Platform:: GPL1790
51 Samples

Download data

Series

Accession:: GSE2143

ID:: 200002143

Select item 10000179011.

Agilent-TQ Cardiovascular Human Oligonucleotide Array

(Submitter supplied) Cardiovascular specific human oligonucleotide array (20433 unique probes) developed between Agilent Technologies and the Quertermous Lab at Stanford University.

Organism:: Homo sapiens

1 DataSet
1 Series
51 Samples

Download data

Platform

Accession:: GPL1790

ID:: 100001790

PubMed Similar studies

Select item 159712.

Coronary artery atherosclerosis

Analysis of 51 coronary artery segments from the explanted hearts of 22 cardiac patients. Results provide insight into the pathogenesis and progression of atherosclerotic disease.

Organism:: Homo sapiens

Type:: Expression profiling by array, log2 ratio, 22 individual sets

Platform:: GPL1790
Series:: GSE2143
51 Samples

Download data

DataSet

Accession:: GDS1597

ID:: 1597

Select item 20011625013.

RNA-seq of heart failure in human left ventricles

(Submitter supplied) The goal of this dataset was to use RNA-seq in human heart tissue to delineate etiology-specific gene expression signatures in heart failure.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
64 Samples

Download data: TXT

Series

Accession:: GSE116250

ID:: 200116250

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20000252114.

Platform Comparison Study

(Submitter supplied) Microarray technology is a powerful tool able to measure RNA expression for thousands of genes at once. Various studies have been published comparing competing platforms with mixed results: some find agreement, others do not. As the number of researchers starting to use microarrays and the number of cross platform meta-analysis studies rapidly increase, appropriate platform assessments become more important. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

4 related Platforms
32 Samples

Download data

Series

Accession:: GSE2521

ID:: 200002521

Select item 20000251215.

Multiple Lab Comparison of Microarray Platforms

(Submitter supplied) A consortium of ten labs from the DC and Baltimore area was formed to compare three leading platforms. Each lab was given identical RNA samples (A1 and B1) which were processed according to what each lab considered best practice. Five of the labs used Affymetrix GeneChips, three used two-color spotted cDNA arrays, and two used two-color long oligo arrays. Keywords: repeat sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1953
4 Samples

Download data

Series

Accession:: GSE2512

ID:: 200002512

Select item 20001604916.

Expression in myocardial tissues of Great Dane dogs with cardiomyopathy

(Submitter supplied) Oligonucleotide microarray analysis of left ventricular tissues from 3 Great dane dogs with dilated cardiomyopathy and 3 control dogs was performed. Three hundred and twenty three differentially expressed transcripts were detected. The transcript demonstrating the highest degree of upregulation was FKBP12.6 (calstabin2) and the transcript with the greatest amount of down regulation was triadin. Both of these transcripts are critical to proper functioning of the cardiac ryanodine receptor. more...

Organism:: Canis lupus familiaris

Type:: Expression profiling by array

Platform:: GPL3738
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE16049

ID:: 200016049

Select item 20004343517.

Thymidine Kinase and mtDNA Depletion in Human Cardiomyopathy: Epigentic and Translational Evidence for Energy Starvation

(Submitter supplied) A comparison of epigenetic nuclear DNA methylation and gene expression changes between human dialated cardiomypathy left ventricle samples and non-failing cardiac left ventricule samples This study addresses how depletion of huaman cardiac left ventricle mitochondrial DNA and epigentic nuclear DNA methylation promote cardiac dysfunction in human dilated cardiomyopathy.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by genome tiling array

Platforms:: GPL15338 GPL16284
40 Samples

Download data: CALLS, GFF, PAIR, TXT

Series

Accession:: GSE43435

ID:: 200043435

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20022421118.

Identification of signature genes of Dilated cardiomyopathy Using Integrated bioinformatics analysis

(Submitter supplied) Dilated cardiomyopathy (DCM) is characterized by left ventricular or biventricular enlargement with systolic dysfunction. To date, the underlying molecular mechanisms of dilated cardiomyopathy pathogenesis have not been fully elucidated, although some insights have been presented. In this study, we combined public database resources and a doxorubicin-induced DCM mouse model to explore the significant genes of DCM in full depth. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28330
6 Samples

Download data: TXT

Series

Accession:: GSE224211

ID:: 200224211

PubMed Full text in PMC Similar studies

Select item 20000201419.

Molecular classification of failing hearts from coronary and myopathic patients

(Submitter supplied) RNA form the heart a goupe of 9 patients with end stage cardiomyopathy (CAD) and 11 patiensts with coronary artery disease (CAD) was hybridized against pooled RNA form 4 normal nonfailing hearts. Keywords: repeat sample