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Series GSE43435 Query DataSets for GSE43435
Status Public on Jun 05, 2013
Title Thymidine Kinase and mtDNA Depletion in Human Cardiomyopathy: Epigentic and Translational Evidence for Energy Starvation
Organism Homo sapiens
Experiment type Expression profiling by array
Methylation profiling by genome tiling array
Summary A comparison of epigenetic nuclear DNA methylation and gene expression changes between human dialated cardiomypathy left ventricle samples and non-failing cardiac left ventricule samples
This study addresses how depletion of huaman cardiac left ventricle mitochondrial DNA and epigentic nuclear DNA methylation promote cardiac dysfunction in human dilated cardiomyopathy.
Overall design Each sample was fluorescently labeled and hybridized to Roche Nimblegen 2.1M Deluxe Promoter Arrays and Expression arrays.
Contributor(s) Koczor CA, Lewis W
Citation(s) 23695888, 23695887
Submission date Jan 10, 2013
Last update date Jun 05, 2013
Contact name William Lewis
Organization name Emory University
Department Pathology
Lab Lewis Lab
Street address 101 Woodruff Circle
City Atlanta
State/province Georgia
ZIP/Postal code 30322
Country USA
Platforms (2)
GPL15338 Nimblegen Homo sapiens HG18 Expression Array (12x135k) [gene-level]
GPL16284 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
Samples (40)
GSM1062380 NF2 mRNA
GSM1062381 NF3 mRNA
GSM1062382 NF4 mRNA
BioProject PRJNA186556

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE43435_RAW.tar 2.4 Gb (http)(custom) TAR (of CALLS, GFF, PAIR, TXT)
Processed data included within Sample table
Processed data provided as supplementary file

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