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Links from GEO DataSets

Items: 18

1.

Two circadian oscillatory mechanisms in the mouse liver

(Submitter supplied) Genome-wide expression analysis of two circadian oscillatory mechanisms in the mouse liver To identify the genes of which the circadian expression is regulated by endogenous glucocorticoids, we performed DNA microarray analysis using hepatic RNA from adrenalectomized (ADX) and sham-operated mice. Mice were housed in a 12:12 h light-dark cycle (LD12:12; lights on at zeitgeber time (ZT) 0) for at least two weeks before the day of the experiment. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1870
Platform:
GPL81
4 Samples
Download data: CEL, EXP, RPT, TXT
Series
Accession:
GSE2162
ID:
200002162
2.
Full record GDS1870

Adrenalectomized liver at light and dark periods of the circadian cycle

Expression profiling of livers of adrenalectomized C57BL/6 males 2 hours into the light or dark periods of a 12:12 hour light cycle. Results identify genes regulated by endogenous glucocorticoids in a circadian manner.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 protocol, 2 time sets
Platform:
GPL81
Series:
GSE2162
4 Samples
Download data: CEL, EXP, RPT, TXT
DataSet
Accession:
GDS1870
ID:
1870
3.

Wildtype and Per2Cry1 double mutant mice: temporal gene expression profiling of adrenal gland

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
30 Samples
Download data
Series
Accession:
GSE4253
ID:
200004253
4.

rhythmic transcriptome in the murine wt adrenal

(Submitter supplied) This study was performed to characterize the rhythmic transcirptome of the murine adrenal gland with a focus on the corticosterone synthesis pathway. Keywords: time course
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2232
Platform:
GPL1261
24 Samples
Download data
Series
Accession:
GSE4238
ID:
200004238
5.
Full record GDS2232

Adrenal gland in constant darkness: time course

Analysis of adrenal glands of wild type animals at various time points after transferring the animals from a light-day cycle to constant darkness. Results provide insight into the function of the adrenal cortical clock.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 12 time sets
Platform:
GPL1261
Series:
GSE4238
24 Samples
Download data
DataSet
Accession:
GDS2232
ID:
2232
6.

Circadian rhythm in Clock mutant and Cry deficient mice

(Submitter supplied) Molecular analysis of circadian rhythm in mice. Liver tissue of wildtype, Clock mutant and Cry deficient C57BL/6 8- to 10-week-old male mice examined. Keywords = circadian rhythm Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS413
Platform:
GPL81
6 Samples
Download data
Series
Accession:
GSE454
ID:
200000454
7.
Full record GDS413

Circadian rhythm in Clock and Cry mutants

Identification of CLOCK and CRY-regulated genes expressed in circadian manner in liver. Wild-type, Clock mutant and Cry-deficient C57BL/6 8-10 week old male mice examined at circadian times (CT) 14 and 2.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 strain, 2 time sets
Platform:
GPL81
Series:
GSE454
6 Samples
Download data
DataSet
Accession:
GDS413
ID:
413
8.

Transcriptome regulation in the adrenal gland of circadian clock deficient Per2Cry1 double mutant mice

(Submitter supplied) This array set was used to determine clock regulated genes in the adrenal gland that are not necessarily rhythmic but still controlled by the circadian TTL. Keywords: comparative genomic hybridization / time series
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2233
Platform:
GPL1261
6 Samples
Download data
Series
Accession:
GSE4239
ID:
200004239
9.
Full record GDS2233

Circadian clock deficient Per2/Cry1 double mutant adrenal gland in constant darkness: time course

Analysis of adrenal glands of Per2/Cry1 double mutant animals at 46 and 54 hours after transferring the animals from a light-day cycle to constant darkness. Per2/Cry1 double mutants lack a circadian clock. Results identify clock-regulated genes in the adrenal that are not necessarily rhythmic.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 time sets
Platform:
GPL1261
Series:
GSE4239
6 Samples
Download data
DataSet
Accession:
GDS2233
ID:
2233
10.

Hepatic Gene Expression Changes Throughout the Day in the Fischer Rat

(Submitter supplied) One µg of total RNA from either an individual rat or from a pooled sample was amplified and labeled with a fluorescent dye (either Cy3 or Cy5) using the Low RNA Input Linear Amplification Labeling kit (Agilent Technologies, Palo Alto, CA) following the manufacturer’s protocol. The amount and quality of the resulting fluorescently labeled cRNA was assessed using a Nanodrop ND-100 spectrophometer and an Agilent Bioanalyzer. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL890
20 Samples
Download data
Series
Accession:
GSE2441
ID:
200002441
11.

Circadian Profiling of NIH3T3 Fibroblasts: Comparison with Rhythmic Gene Expression in SCN2.2 Cells and the Rat SCN

(Submitter supplied) To screen for specific circadian outputs that may distinguish the pacemaker in the mammalian suprachiasmatic nucleus (SCN) from peripheral-type oscillators in which the canonical clockworks are similarly regulated in a circadian manner, the rhythmic behavior of the transcriptome in forskolin-stimulated NIH/3T3 fibroblasts was analyzed and compared to that found in the rat SCN in vivo and SCN2.2 cells in vitro. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL81
27 Samples
Download data: CEL
Series
Accession:
GSE5810
ID:
200005810
12.

Expression data of mouse fetal liver during embryonic day 18 and 19

(Submitter supplied) The oscillation status of the circadian clock during late gestation is not clear. To gain a better understanding on the oscillation state of the clock and possible influences by maternal cues, we performed transcriptome analyses on the fetal liver tissue during late gestation. Fetal liver transcriptome data were analyzed and compared to adult mouse data in the public database: GSE11923 and GSE13093 (only samples GSM327130 to GSM327141). more...
Organism:
Mus musculus
Type:
Expression profiling by array; Third-party reanalysis
Platform:
GPL8321
24 Samples
Download data: CEL, TXT
Series
Accession:
GSE28622
ID:
200028622
13.

Liver treatments Con, Veh, Dex

(Submitter supplied) Mouse liver RNA was extracted using Trizol (Invitrogen) and Qiagen RNeasy kits. RNA was checked with an Agilent Bioanalyzer for evidence of sub-genomic DNA and degradation. Targets were produced using standard Affymetrix protocols. Each sample represents data from a single mouse liver. Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL81
27 Samples
Download data
Series
Accession:
GSE564
ID:
200000564
14.

High temporal resolution profiling of U2OS fibroblasts

(Submitter supplied) High-temporal resolution profiling was performed on U2OS fibroblasts to detect rhythmic transcripts Keywords: time course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
48 Samples
Download data: CEL, CHP
Series
Accession:
GSE13949
ID:
200013949
15.

High-temporal resolution profiling of mouse liver

(Submitter supplied) High-temporal resolution profiling was performed on mouse liver to detect rhythmic transcripts Keywords: time course
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
48 Samples
Download data: CEL
Series
Accession:
GSE11923
ID:
200011923
16.

High temporal resolution profiling of NIH3T3 cells

(Submitter supplied) High-temporal resolution profiling was performed on NIH3T3 fibroblasts to detect rhythmic transcripts Keywords: time course
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
48 Samples
Download data: CEL
Series
Accession:
GSE11922
ID:
200011922
17.

Normalisation Against Circadian and Age-related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice

(Submitter supplied) Pilot experiment to uncover age-related changes of the mouse liver transcriptome derived from healthy male mice. To avoid bias, RNA samples from multiple time points over the day were combined.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15907
4 Samples
Download data: TXT
Series
Accession:
GSE79199
ID:
200079199
18.

Transcriptional responses to i.v. administered I-131 in various mouse normal tissues underlie diurnal variation

(Submitter supplied) Circadian rhythm study on transcriptional responses to i.v. administered 90 kBq iodine-131 after 24h in mouse kidney cortex and medulla, liver, lungs, spleen, and thyroid. Female BALB/c nude mice (n=4/group) were i.v. injected with 90 kBq 131I at three different times of day, i.e. at 9.00 am, at 12.00 pm, or at 3.00 pm, and killed under anesthesia after 24h following treatment for excision of organs. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
136 Samples
Download data: TXT
Series
Accession:
GSE66303
ID:
200066303
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Supplemental Content

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