Circadian clock deficient Per2/Cry1 double mutant adrenal gland in constant darkness: time course
Summary:
Analysis of adrenal glands of Per2/Cry1 double mutant animals at 46 and 54 hours after transferring the animals from a light-day cycle to constant darkness. Per2/Cry1 double mutants lack a circadian clock. Results identify clock-regulated genes in the adrenal that are not necessarily rhythmic.
Oster H, Damerow S, Kiessling S, Jakubcakova V et al. The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock. Cell Metab 2006 Aug;4(2):163-73. PMID: 16890544
