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Links from GEO DataSets

Items: 18

1.
Full record GDS412

Amyotrophic lateral sclerosis (Lou Gehrig's Disease)

Identification of amyotrophic lateral sclerosis (ALS) associated genes. Post mortem spinal cord grey matter from sporadic and familial ALS patients compared with controls. Attempt to identify mechanisms by which ALS destroys motor neurons.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL80
Series:
GSE833
11 Samples
Download data
DataSet
Accession:
GDS412
ID:
412
2.
Full record GDS2790

Skeletal muscle response to insulin infusion (HuGeneFL)

Analysis of skeletal muscles from non-diabetics after a 3 hour infusion of insulin. Glucose uptake by skeletal muscles in response to insulin is impaired in type 2 diabetes. Results provide insight into the molecular mechanisms regulating glucose homeostasis in response to insulin.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL80
Series:
GSE7146
12 Samples
Download data: CEL
3.
Full record GDS2489

Large airway epithelium response to cigarette smoking (HuGeneFL)

Analysis of large airway epithelial cells of phenotypically normal smokers. Lung cancer tumors exhibit neuroendocrine properties, and chronic smokers have increased numbers of neuroendocrine cells. Results provide insight into the effect of cigarette smoking on neuroendocrine cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 stress sets
Platform:
GPL80
Series:
GSE5056
44 Samples
Download data
DataSet
Accession:
GDS2489
ID:
2489
4.
Full record GDS1645

Nitric oxide effect on soluble guanylate cyclase deficient cells

Analysis of soluble guanylate cyclase-deficient U937 cells exposed to the nitric oxide (NO) donor S-nitrosoglutathione. Cells treated in the presence of dibutyryl-cAMP (Bt2cAMP) to block signaling due to NO-induced decreases in cAMP. Results provide insight into the cGMP-independent effects of NO.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 5 agent, 2 development stage sets
Platform:
GPL80
Series:
GSE2649
42 Samples
Download data
5.
Full record GDS1440

Melanoma cell lines treated with a DNA methylase inhibitor

Analysis of a poorly tumorigenic melanoma cell line and its 3 highly aggressive derivative lines after treatment with 2'-deoxy-5-azacytidine (DAC), a DNA methyltransferase inhibitor. Results suggest multiple markers for melanoma progression that are regulated by DNA methylation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 4 cell line, 2 cell type sets
Platform:
GPL80
Series:
GSE1793
6 Samples
Download data
DataSet
Accession:
GDS1440
ID:
1440
6.
Full record GDS1436

Cigarette smoking effect on alveolar macrophages

Anlaysis of alveolar macrophages of 5 phenotypically normal smokers who consume ~20 packs cigarettes/year. Smoking is the leading cause of respiratory diseases collectively known as chronic obstructive pulmonary disease (COPD). Provides insight into early events in molecular pathogenesis of COPD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 stress sets
Platform:
GPL80
Series:
GSE3212
10 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1436
ID:
1436
7.
Full record GDS1210

Gastric cancer

Expression profiling of 22 primary advanced gastric cancer tissues. Whole gastric cancer tissues examined in the presence of metastasis and according to histological type. Results provide insight into the progression and diversity of gastric cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL80
Series:
GSE2685
30 Samples
Download data
DataSet
Accession:
GDS1210
ID:
1210
8.
Full record GDS781

CD14 cells from granulocyte colony stimulating factor mobilized peripheral blood: expression profile

Expression profiling of CD14+ cells isolated from granulocyte colony stimulating factor (G-CSF) mobilized peripheral blood mononuclear cells (G-PBMC). Cells collected from normal donors after 3 days of G-CSF stimulation. G-PBMCs may confer a survival advantage to allogeneic transplant recipients.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL80
Series:
GSE1746
10 Samples
Download data: CEL
DataSet
Accession:
GDS781
ID:
781
9.
Full record GDS670

Emphysema lung tissue expression profiling

Expression profiling of lung tissue from normal individuals, and patients with either 'usual' emphysema or alpha-1 antitrypsin (AAT) deficiency-related emphysema. Global reduction in gene expression observed in emphysemic lungs.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL80
Series:
GSE1122
15 Samples
Download data: CEL
DataSet
Accession:
GDS670
ID:
670
10.
Full record GDS533

Uterine smooth muscle tumor characterization

Comparison of gene expression in uterine smooth muscle tumors. Normal myometrium, benign uterine leiomyoma, malignant uterine and extra-uterine leiomyosarcoma examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 tissue sets
Platform:
GPL80
Series:
GSE764
24 Samples
Download data
DataSet
Accession:
GDS533
ID:
533
11.
Full record GDS504

Pulmonary arterial hypertension and PBMC

Analysis of peripheral blood mononuclear (PBMC) cells in patients with pulmonary arterial hypertension (PAH). Altered gene expression patterns in PAH PBMCs may allow disease subgroup identification and prediction of treatment response.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL80
Series:
GSE703
20 Samples
Download data
DataSet
Accession:
GDS504
ID:
504
12.
Full record GDS337

Telomerase overexpression

Effect of overexpression of the telomerase catalytic subunit (TERT) in mammary epithelial cells (HMEC). Findings imply that ectopic telomerase expression modulates growth-controlling genes and enhances cell proliferation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 cell line sets
Platform:
GPL80
Series:
GSE361
20 Samples
Download data
DataSet
Accession:
GDS337
ID:
337
13.
Full record GDS258

Juvenile dermatomyositis muscle profile (HuGeneFL)

Examination of skeletal muscle from juvenile dermatomyositis (JDM) patients, a common pediatric inflammatory myopathy. Muscle biopsies processed singly or in mixed groups of two. Patients genotyped for TNFalpha which is associated with prolonged disease.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 8 specimen sets
Platform:
GPL80
Series:
GSE493
10 Samples
Download data: CEL
DataSet
Accession:
GDS258
ID:
258
14.
Full record GDS183

Bladder tumor stage classification

Identification of clinically relevant subclasses of bladder carcinoma. Three major stages identified, Ta, T1 and T2-4. Ta tumors further classified into subgroups. A 32-gene molecular classifier was built.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 4 tissue sets
Platform:
GPL80
Series:
GSE89
40 Samples
Download data: CEL
DataSet
Accession:
GDS183
ID:
183
15.
Full record GDS172

SIV disease progression

Analysis of SIV MAC 251 disease progression in Rhesus Macaque peripheral blood mononuclear cells (PBMC). Slow, typical and fast progression groups examined at baseline, 3 and 7 weeks post-infection.
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by array, count, 3 other, 3 time sets
Platform:
GPL80
Series:
GSE512
36 Samples
Download data
DataSet
Accession:
GDS172
ID:
172
16.
Full record GDS171

HIV viral infection time course

Gene expression profile of proliferating normal peripheral blood mononuclear cells (PBMC) infected with HIV type 1 RF. Assessed at 0, 12, 24, 48, and 72 hours postinfection and compared with those of matched uninfected PBMC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 infection, 5 time sets
Platform:
GPL80
Series:
GSE511
30 Samples
Download data
DataSet
Accession:
GDS171
ID:
171
17.
Full record GDS170

Tumor suppressor protein p53 gene dosage effects

Analysis of tumor suppressor protein p53 gene dosage effects in HCT116 colorectal carcinoma-derived cell lines p53 -/-, +/- and +/+ at 0 and 12 hours. Cells with different numbers of functional TP53 alleles can be distinguished by gene expression profile.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 strain, 2 time sets
Platform:
GPL80
Series:
GSE90
12 Samples
Download data
18.
Full record GDS157

Type 2 diabetes and insulin resistance (HuGeneFL)

Analysis of gene expression in pooled vastus lateralis muscle samples from insulin-sensitive and insulin-resistant equally obese, non-diabetic Pima Indians. A search for susceptibility genes for type 2 diabetes.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 metabolism sets
Platform:
GPL80
Series:
GSE121
10 Samples
Download data
DataSet
Accession:
GDS157
ID:
157
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