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Items: 11

1.

Gene expression profiling with hypoxia and BRD-K34222889 from primary human pulmonary artery endothelial cells (HPAECs)

(Submitter supplied) BRD-K34222889 is a structural analog of the anti-inflammatory and senolytic drug piperlongumine. Piperlongumine inhibits GSTP1, an enzyme that places glutathione moieties on cysteine residues of various protein targets and for modulation of protein stability. The objective of this experiment was to determine the effect of a Piperlongumine analog BRD-K34222889 in endothelial dysfunction. Interestingly, BRD-K34222889 was found to inhibit glutathione S-transferase P (GSTP1), which increased ISCU protein stability via preventing glutathionylation and thus increased oxidative metabolism and decreased PAEC apoptosis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL23159
9 Samples
Download data: CEL, CHP, XLSX
Series
Accession:
GSE160255
ID:
200160255

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay)

(Submitter supplied) This platform supports submissions for: Clariom S Assay: https://www.thermofisher.com/order/catalog/product/902926 Clariom S Pico Assay https://www.thermofisher.com/order/catalog/product/902928 Annotations: #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg38 #%genome-version-ucsc=hg38 #%genome-version-ncbi=GRCh38 #%genome-version-create_date=2013-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg38 #%genome-lifted_from-version-ncbi=GRCh38 #%netaffx-annotation-date=2016-06-03 #%netaffx-annotation-netaffx-build=36 Protocol: See manufacturer's website
Organism:
Homo sapiens
524 Series
3 Related Platforms
7808 Samples
Download data
Platform
Accession:
GPL23159
ID:
100023159

3.

HPAECs, Normoxia-3

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869884
ID:
304869884

4.

HPAECs, Normoxia-2

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869883
ID:
304869883

5.

HPAECs, Normoxia-1

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869882
ID:
304869882

6.

HPAECs, Hypoxia+BRD-3

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869881
ID:
304869881

7.

HPAECs, Hypoxia+BRD-2

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869880
ID:
304869880

8.

HPAECs, Hypoxia+BRD-1

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869879
ID:
304869879

9.

HPAECs, Hypoxia-3

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869878
ID:
304869878

10.

HPAECs, Hypoxia-2

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869877
ID:
304869877

11.

HPAECs, Hypoxia-1

Organism:
Homo sapiens
Source name:
primary pulmonary artery endothelial cells
Platform:
GPL23159
Series:
GSE160255
Download data: CEL, CHP
Sample
Accession:
GSM4869876
ID:
304869876

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